「clo」の検索結果

Automate Cloudinary media management including folder organization, upload presets, asset lookup, transformations, and usage monitoring through natural language commands

日本語の概要は準備中です。原文の説明を表示しています。

Automate Cloudcart tasks via Rube MCP (Composio). Always search tools first for current schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Automate time tracking workflows in Clockify -- create and manage time entries, workspaces, and users through natural language commands.

日本語の概要は準備中です。原文の説明を表示しています。

Automate Cloudconvert tasks via Rube MCP (Composio). Always search tools first for current schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Automate Big Data Cloud tasks via Rube MCP (Composio). Always search tools first for current schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Performs proximity operations on genomic intervals with bedtools (closest, window, flank, slop) and pybedtools - nearest-feature queries with signed/strand-aware distance, fixed-radius window searches, strand-aware promoter construction, and interval extension. Covers the closest -d/-D a/b/ref/-t/-k/-io/-iu/-id flags, the -D ref strand sign-flip, silent chromosome-end clipping in slop/flank, -t all tie double-counting, and the critical distinction between a geometry answer (nearest TSS) and a biology answer (which gene an element regulates). Use when assigning peaks or variants to genes, defining promoters from a gene model, building distance-to-TSS distributions, finding features within a window, or extending intervals - and when deciding whether nearest-gene is a fair prior (GWAS locus) or a trap (distal enhancer).

日本語の概要は準備中です。原文の説明を表示しています。

Download raw sequencing reads from NCBI SRA using sra-tools (prefetch, fasterq-dump, vdb-validate) or the ENA mirror. Use when pulling FASTQ for SRR/ERR/DRR accessions, deciding between SRA-direct, ENA mirror, or AWS/GCP cloud mirror (STRIDES), handling --include-technical for 10x and other single-cell records, validating with MD5/vdb-validate, navigating SRR/SRX/SRS/SRP/PRJNA hierarchy, or finding accessions via pysradb. Encodes SRA cloud-egress economics, the fasterq-dump uncompressed-scratch trap, and the --max-size default that silently truncates large prefetches.

日本語の概要は準備中です。原文の説明を表示しています。

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

日本語の概要は準備中です。原文の説明を表示しています。

Designs and analyzes in vivo CRISPR screens in animal tumor models, organoids, and immune-cell adoptive transfers. Covers bottleneck math (250x cells/sgRNA requires ~25M cells implanted; impossible for most syngeneic models, forcing focused libraries), focused library design (Manguso 2017 Nature 547:413 immune screen; Chen 2015 tumor screens), CRISPR-StAR intrinsic-control screening (Uijttewaal 2025 Nat Biotechnol 43:1848), clonal-dynamics-limited detection, tumor-explant DNA recovery, syngeneic vs xenograft vs PDX considerations, and the relationship to downstream MAGeCK / drugZ analysis. Use when designing in vivo CRISPR screens for tumor / immune / metastasis biology, choosing focused vs genome-wide for animal models, addressing bottleneck-induced clonal collapse, picking the syngeneic / xenograft / PDX model, integrating in vivo with in vitro results, or applying CRISPR-StAR for animal experiments.

日本語の概要は準備中です。原文の説明を表示しています。

Designs pooled sgRNA libraries for CRISPR knockout, interference (CRISPRi), activation (CRISPRa), Cas12a multiplex, base-editor, and prime-editor screens. Covers on-target scoring (Rule Set 2, Azimuth, DeepSpCas9, CRISPRon), off-target scoring (CFD, MIT), TSS-relative positioning for CRISPRi/a (Horlbeck, Dolcetto, Calabrese), PAM-variant chemistries, control-guide composition, oligo cloning architecture, and library QC. Use when choosing a genome-wide library (GeCKOv2 vs Avana vs Brunello vs TKOv3 vs Inzolia), designing a focused or paralog-focused custom library, picking CRISPRi vs CRISPRa TSS windows, deciding control-guide proportions, or diagnosing library skew and dropout in a freshly cloned pool.

日本語の概要は準備中です。原文の説明を表示しています。

Expert debugger for Next.js + Cloudflare Workers + Supabase stacks. Systematic troubleshooting for auth, caching, workers, RLS, CORS, and build issues. Activate on: 'debug', 'not working', 'error', 'broken', '500', '401', '403', 'cache issue', 'RLS', 'CORS'. NOT for: feature development (use language skills), architecture design (use system-architect).

日本語の概要は準備中です。原文の説明を表示しています。

Create and review Cloudflare Durable Objects. Use when building stateful coordination (chat rooms, multiplayer games, booking systems), implementing RPC methods, SQLite storage, alarms, WebSockets, or reviewing DO code for best practices. Covers Workers integration, wrangler config, and testing with Vitest. Biases towards retrieval from Cloudflare docs over pre-trained knowledge.

日本語の概要は準備中です。原文の説明を表示しています。

Structure persuasive speeches and formal arguments in forensic, legal, policy, and competitive debate styles. Use when the user needs to prepare talks, opening or closing arguments, policy pitches, public explanations, debate speeches, or mentions 'forensic speech', 'formal argument', 'persuasive speech structure', 'debate speech', 'opening statement', 'closing argument'. Turns structured claims into audience-tuned persuasive delivery.

日本語の概要は準備中です。原文の説明を表示しています。

Frontend stack decisions, Cloudflare deployment patterns, component systems, and internal tools architecture. Use for framework selection, deployment strategy, design system bridging, shadcn setup. Activate on "frontend architecture", "tech stack", "Cloudflare Pages", "component library", "internal tools", "shadcn setup". NOT for writing CSS (use frontend-developer), design critique (use design-critic), or backend APIs.

日本語の概要は準備中です。原文の説明を表示しています。

Write production-grade Dockerfiles, docker-compose configurations, multi-stage builds, and container optimization. Activate on "Dockerfile", "docker", "docker-compose", "container", "multi-stage build", "docker image", "container optimization", "docker security". NOT for Kubernetes orchestration, cloud-specific container services (ECS, Cloud Run), or CI/CD pipelines (use github-actions-pipeline-builder).

日本語の概要は準備中です。原文の説明を表示しています。

Send and receive transactional emails with Cloudflare Email Service (Email Sending + Email Routing). Use when building email sending (Workers binding or REST API), email routing, Agents SDK email handling, or integrating email into any app — Workers, Node.js, Python, Go, etc. Also use for email deliverability, SPF/DKIM/DMARC, wrangler email setup, MCP email tools, or when a coding agent needs to send emails. Even for simple requests like "add email to my Worker" — this skill has critical config details.

日本語の概要は準備中です。原文の説明を表示しています。

Designs and audits native-unit capacity reservation, serial admission, ambiguity holds, stop reserves, effect closure, and control-disjoint settlement handoff for consequential agent attempts. Use when scarce capacity must be conserved across retry, rework, resurrection, or compensation. NOT for scheduling work, choosing models, pricing unlike resources into one scalar, authorizing effects, grading work, paying workers, or asserting runtime containment.

日本語の概要は準備中です。原文の説明を表示しています。

Designing HTTP cache headers that work correctly across browsers, CDNs, and shared proxies — `Cache-Control` directives per RFC 9111, `stale-while-revalidate` and `stale-if-error` per RFC 5861, the Vary header for varying responses, and surrogate keys for tag-based purging. Grounded in IETF RFCs and Cloudflare/Fastly docs. NOT for service-worker or browser-only caching, Redis/memcached application caching, or edge-function compute.

日本語の概要は準備中です。原文の説明を表示しています。

Plans migrations from Zscaler ZIA/ZPA, Palo Alto, legacy VPN, SWG, or SASE stacks to Cloudflare One. Use for migration assessments, policy mapping, rollout plans, and parity/gap analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Declare an agentic application's interaction disclosure, state, context, capabilities, and effect-control boundaries. Use for a reviewable design specification and static consistency audit before implementation. NOT for proving that controls are deployed or enforced, exposing private chain-of-thought, selecting a model/router, or designing a multi-agent protocol.

日本語の概要は準備中です。原文の説明を表示しています。

Expert in script-to-video production pipelines for Apple Silicon Macs. Specializes in hybrid local/cloud workflows, LoRA training for character consistency, motion graphics generation, and artist commissioning. Activate on 'AI video production', 'script to video', 'video generation pipeline', 'character consistency', 'LoRA training', 'cloud GPU', 'motion graphics', 'Wan I2V', 'InVideo alternative'. NOT for real-time video editing, video compositing (use DaVinci/Premiere), audio production, or 3D modeling (use Blender/Maya).

日本語の概要は準備中です。原文の説明を表示しています。

Build voice AI agents with LiveKit Cloud and the Agents SDK. Use when the user asks to "build a voice agent", "create a LiveKit agent", "add voice AI", "implement handoffs", "structure agent workflows", or is working with LiveKit Agents SDK. Provides opinionated guidance for the recommended path: LiveKit Cloud + LiveKit Inference. REQUIRES writing tests for all implementations.

日本語の概要は準備中です。原文の説明を表示しています。

Layout structure for web interfaces, from grouping and alignment to reading order, progressive disclosure, and adaptive breakpoints. Use when structuring a page or component, spacing or aligning controls, deciding what collapses at small sizes, handling RTL layout direction, or reviewing frontend code for layout. Triggers on layout, spacing, alignment, grouping, negative space, whitespace, visual hierarchy, reading order, progressive disclosure, breakpoints, responsive layout, container queries, safe area, full-bleed, edge-to-edge, layout margins, RTL layout, logical properties.

日本語の概要は準備中です。原文の説明を表示しています。

[74] CLOSE. Quick checkpoint during active work when context is running low. Use multiple times per development cycle to preserve progress and lessons. Lighter than close-session — no full handoff needed. Triggers on 'save progress', 'checkpoint', 'context low', or automatically when nearing token limits.

日本語の概要は準備中です。原文の説明を表示しています。