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概要と使いどころ
Parse local DrugBank XML for drug info, interactions, targets, and properties. Search by ID/name/CAS, extract DDIs with severity, map targets/enzymes/transporters, compute SMILES similarity. Primary via local XML; REST API rate-limited (3k/month dev). For live bioactivity use chembl-database-bioactivity; for compound properties use pubchem-compound-search.
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Look up EMDB cryo-EM density maps and fitted atomic models via the entry REST API + EBI Search WS. Fetch entry metadata (resolution, method, organism, sample), map download URLs, fitted PDB IDs, and citations. Keyword search via EBI Search. No auth. For atomic coordinates use pdb-database; for AlphaFold predictions use alphafold-database-access.
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Query RCSB PDB (200K+ structures) via the public REST + GraphQL APIs with plain `requests` (no SDK). Search by text, attribute, sequence, or 3D structure similarity (Search API); retrieve metadata via GraphQL (Data API); download PDB/mmCIF from files.rcsb.org. For AlphaFold predictions use alphafold-database-access; for protein sequences only use uniprot-protein-database.
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Query the ZINC22 virtual compound library (CartBlanche API, billions of make-on-demand + purchasable molecules). Look up substances by ZINC ID, resolve a SMILES to its ZINC ID (exact match), inspect purchasability/catalogs, and assemble compound sets for docking. Property (MW/logP) filtering is done locally with RDKit. For bioactivity use chembl-database-bioactivity; for approved drugs use drugbank-database-access.
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Query IUPHAR/BPS Guide to Pharmacology (GtoPdb) for receptor-ligand interactions, target/ligand metadata, families, and approved drugs. Affinities (pKi/pIC50/pKd), action (Agonist/Antagonist/etc.), species, structures (SMILES/InChI). No auth. Always resolve targets via geneSymbol/accession; most metadata lives in sub-resources (/databaseLinks, /structure, /synonyms).
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Research posters in LaTeX using beamerposter, tikzposter, or baposter. Layout, typography, color schemes, figure integration, accessibility, and QA for conferences. Includes templates. For figure generation use matplotlib-scientific-plotting or plotly-interactive-plots.
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Programmatic PubMed access via NCBI E-utilities REST API. Covers Boolean/MeSH queries, field-tagged search, endpoints (ESearch, EFetch, ESummary, EPost, ELink), history server for batches, citation matching, systematic review strategies. Use for biomedical literature search or automated pipelines.
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Access USPTO patent data via PatentsView REST API and Google Patents Public Data (BigQuery). Search by inventor, assignee, CPC, or keywords; download metadata and claims; analyze portfolios; track tech trends. For IP landscape analysis, competitor monitoring, prior art search, and tech forecasting in life sciences and biotech.
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Guide for choosing and creating scientific visualizations for publications and talks. Covers chart-type selection by data structure, color theory for accessibility/print, figure composition, journal formatting (Nature, Cell, ACS), and common pitfalls. Consult when visualizing data or preparing submission figures.
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Predict RNA secondary structure, MFE folding, base-pair probabilities, RNA-RNA interactions via ViennaRNA Python bindings. Pipeline: sequence → MFE → partition function and pair-probability matrix → dot-bracket → duplex. Use for siRNA/sgRNA targeting, ribozyme design, RNA accessibility. Use RNAfold CLI for batch use without Python.
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Parse HMDB (Human Metabolome Database) local XML for metabolite info, chemical properties, biological context, disease links, spectra, and cross-DB mapping. No REST API — uses ~6 GB XML download. Use drugbank-database-access for drugs; pubchem-compound-search for live lookups.
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Search the PRIDE Archive v3 REST API for proteomics datasets: discover projects by keyword + faceted filters (organism, instrument, disease, software), fetch project metadata, list and download RAW/PEAK/RESULT/FASTA files (with FTP/Aspera URLs), look up which projects mention a UniProt accession, and find similar projects. PRIDE v3 no longer exposes peptide/PSM-level identification endpoints — for spectrum-level data download the project's RESULT files. Use uniprot-protein-database for protein sequences; interpro-database for domain architecture.
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protocols.io REST API: search and fetch wet-lab, bioinformatics, and clinical protocols by keyword, DOI, or category, with steps, reagents, materials, equipment, timing. Public access free; auth needed for private or publishing. Pair with opentrons-protocol-api or benchling-integration to execute.
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Configure AWS MCP servers for documentation search and API access. Use when setting up AWS MCP, configuring AWS documentation tools, troubleshooting MCP connectivity, or when user mentions aws-mcp, awsdocs, uvx setup, or MCP server configuration. Covers both Full AWS MCP Server (with uvx + credentials) and lightweight Documentation MCP (no auth required).
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Provides AWS CloudFormation patterns for IAM roles, policies, managed policies, permission boundaries, and trust relationships. Use when modeling least-privilege access, cross-account assumptions, service roles, or reusable IAM stacks that other CloudFormation templates consume.
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Provides comprehensive code review capability for React applications, validates component architecture, hooks usage, React 19 patterns, state management, performance optimization, accessibility compliance, and TypeScript integration. Use when reviewing React code changes, before merging pull requests, after implementing new features, or for component architecture validation. Triggers on "review React code", "React code review", "check my React components".
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Provides complete shadcn/ui component library patterns including installation, configuration, and implementation of accessible React components. Use when setting up shadcn/ui, installing components, building forms with React Hook Form and Zod, customizing themes with Tailwind CSS, or implementing UI patterns like buttons, dialogs, dropdowns, tables, and complex form layouts.
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Provides authentication implementation patterns for Next.js 15+ App Router using Auth.js 5 (NextAuth.js). Use when setting up authentication flows, implementing protected routes, managing sessions in Server Components and Server Actions, configuring OAuth providers, implementing role-based access control, or handling sign-in/sign-out flows in Next.js applications.
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Provides JWT authentication and authorization patterns for Spring Boot 3.5.x covering token generation with JJWT, Bearer/cookie authentication, database/OAuth2 integration, and RBAC/permission-based access control using Spring Security 6.x. Use when implementing authentication or authorization in Spring Boot applications.
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Provides AWS Secrets Manager patterns for AWS SDK for Java 2.x, including secret retrieval, caching, rotation-aware access, and Spring Boot integration. Use when storing or reading secrets in Java services, replacing hardcoded credentials, or wiring secret-backed configuration into applications.
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Set up the ContextA8C MCP server for accessing Automattic internal resources (Slack, Linear, P2s, GitHub Enterprise, etc.)
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Design, implement, audit, or review Shift user interfaces and shared UI components. Use for React components, Base UI primitives, Tailwind styling or theme tokens, Figma/reference matching, accessibility, icon-only actions, tooltips, menus, popovers, dialogs, forms, layout, and visible UI regressions.
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Use when auditing a specific page's SEO performance, content quality, and competitive position. The agent fetches the URL, Googles the primary keyword, reads the top 3 competitors, and produces a full 7-dimension audit — no exports, no analytics access required.
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Apache Iceberg tables on Databricks — Managed Iceberg tables, External Iceberg Reads (fka Uniform), Compatibility Mode, Iceberg REST Catalog (IRC), Iceberg v3, Snowflake interop, PyIceberg, OSS Spark, external engine access and credential vending. Use when creating Iceberg tables, enabling External Iceberg Reads (uniform) on Delta tables (including Streaming Tables and Materialized Views via compatibility mode), configuring external engines to read Databricks tables via Unity Catalog IRC, integrating with Snowflake catalog to read Foreign Iceberg tables
日本語の概要は準備中です。原文の説明を表示しています。