「binding」の検索結果

Cloud-based quantum chemistry platform with Python API. Preferred for computational chemistry workflows including pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2). Use when tasks involve quantum chemistry calculations, molecular property prediction, DFT or semiempirical methods, neural network potentials (AIMNet2), protein-ligand binding predictions, or automated computational chemistry pipelines. Provides cloud compute resources with no local setup required.

日本語の概要は準備中です。原文の説明を表示しています。

High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.

日本語の概要は準備中です。原文の説明を表示しています。

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

日本語の概要は準備中です。原文の説明を表示しています。

Deploy a free VLESS proxy/VPN node on Cloudflare Pages using edgetunnel. Automates code download, UUID generation, Pages deployment, free domain registration (DNSExit), DNS configuration, custom domain binding, and client setup for Shadowrocket/v2rayN/Clash. Uses Cloudflare Pages (not Workers) because Pages supports CNAME-based custom domains from any DNS provider, avoiding the need to host DNS on Cloudflare.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user has an existing DPDK application and is adding DOCA capabilities in-place — most commonly DOCA Flow hardware steering — without rewriting the data-plane in DOCA-native form: binding a DPDK port id to a `doca_dev` (`doca_dpdk_port_probe` / `doca_dpdk_port_as_dev`), converting `rte_mbuf` ↔ `doca_buf`, querying `doca_dpdk_cap_is_rep_port_supported`, or debugging `DOCA_ERROR_*` from a bridge call. Trigger even without "DOCA DPDK Bridge": "how do I add DOCA Flow to my DPDK app", "make a DPDK port visible to DOCA", "the bridge loads but every operation returns errors", "pkg-config --exists doca-dpdk-bridge fails", or "DOCA_ERROR_NOT_FOUND on port registration". Route elsewhere for fresh DOCA-native packet I/O (doca-eth), flow-rule programming (doca-flow), DOCA or DPDK install (doca-setup), or RDMA data movement (doca-rdma).

日本語の概要は準備中です。原文の説明を表示しています。

Run `doca_bench` (DOCA 2.7.0 or newer) to measure throughput, bulk latency, precision latency, or maximum bandwidth for RDMA, Compress, AES-GCM, SHA, DMA, EC, Ethernet, Comch, or GPUNetIO on a host or BlueField Arm. Use it to discover enabled benchmark libraries, capture a reproducible command/version/device/environment baseline, compare stable runs against a declared tolerance, or diagnose configuration, device-binding, workload-precondition, and measurement failures. Trigger for requests such as measuring BlueField compression speed, NIC RDMA throughput, crypto latency, or a pre-upgrade baseline. Do not use for application end-to-end timing, custom benchmark code, DOCA installation, or binary patches.

日本語の概要は準備中です。原文の説明を表示しています。

PLAINTEXT-ONLY: the shipped `doca_flow_grpc` server uses `grpc::InsecureServerCredentials()` with NO TLS / mTLS / token-auth knob on the binary — transport security must come from external infrastructure (e.g. an mTLS proxy / sidecar) on a trusted segment. Use this skill when bringing up, configuring, hardening, or debugging `doca_flow_grpc` — the DOCA-shipped gRPC remote-control surface in front of `doca-flow` that lets non-C++ clients (Python, Go, Rust, Java) program Flow pipes and entries over RPC instead of linking `libdoca_flow.so` directly. Trigger even when the user doesn't say 'doca-flow-grpc-server' or 'gRPC' — e.g. 'program Flow rules from Python on another host', 'remotely configure pipes on the BlueField', 'client times out connecting to the Flow server', 'where is the .proto for Flow', 'UNAUTHENTICATED / FAILED_PRECONDITION on a Flow RPC'. Route elsewhere for the underlying doca-flow API, generic gRPC tooling (protoc, language bindings), or DOCA install / BFB bring-up.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill for launching, supervising, debugging, OR platform lifecycle on a BlueField — BFB install, RShim/TMFIFO, host PF rebind, post-BFB recovery — taking a DOCA-linked binary to a healthy run directly on hardware (host x86 + BlueField NIC over PCIe, or BlueField Arm bare-metal). No container, no kubelet. Covers launch mode (direct, tmux, systemd), PCI/NUMA/ CPU/IRQ binding, co-tenant isolation (cgroup-v2/netns/numactl), a seven-layer error taxonomy, and a six-state BlueField lifecycle classifier. Trigger even when user does not say "bare-metal" — implicit phrasings include "binary exits 1 right after launch", "systemd keeps restarting it", "no matching device on the BF", "bfb-install exited 0 but DPU is dead", "ping 192.168.100.2 works but ssh fails", "host PFs aren't showing netdevs". Destructive firmware burn / mlxconfig set requires explicit confirmation via doca-hardware-safety; containers, library APIs, env prep, and build use other skills.

日本語の概要は準備中です。原文の説明を表示しています。

Use Boltz2 NIM for biomolecular structure prediction and binding affinity. Invoke for Boltz2, protein structures, protein-ligand/DNA/RNA complexes, SMILES or CCD ligands, pIC50/IC50 affinity scoring, mmCIF output, hosted NVIDIA API calls, or local Docker deployment.

日本語の概要は準備中です。原文の説明を表示しています。

Run DiffDock molecular docking via NVIDIA NIM to predict small-molecule binding poses against protein targets. Use for DiffDock, molecular docking, ligand docking, blind docking, SMILES or SDF ligands, ranked poses, confidence scores, hosted NVIDIA API, or local Docker deployment.

日本語の概要は準備中です。原文の説明を表示しています。

Modify, build, test, debug, and contribute to NVIDIA cuOpt (C++/CUDA, Python, server, CI). Use for solver internals, PRs, DCO, and code conventions.

日本語の概要は準備中です。原文の説明を表示しています。

Private built-in CCB configuration skill for agentroles.ccb_self. Design, edit, validate, and prepare reloads for .ccb/ccb.config, role bindings, providers, windows, workspaces, tool windows, sidebar, and provider startup inputs. Use only inside ccb_self; non-self agents should delegate CCB config changes to ccb_self.

日本語の概要は準備中です。原文の説明を表示しています。

[omh] Aiming for design-award quality: score a web surface against published design-award judging axes and name the binding constraint. Use when the user says: award-bar-score, award bar score, award winning, award-winning, award winning website, award-winning website, award winning design, award ready.

日本語の概要は準備中です。原文の説明を表示しています。

Fetch Evolutionary Conservation scores (phyloP, phastCons) and Transcription Factor Binding Sites (TFBS) from the UCSC Genome Browser. Use when analyzing whether genomic variants or regions are evolutionarily conserved, functionally important, or bounded by TF regulators across major projects (ENCODE, JASPAR, ReMap).

日本語の概要は準備中です。原文の説明を表示しています。

Query the JASPAR database for Transcription Factor (TF) binding profiles. Use when retrieving Position Frequency Matrices (PFMs) or Position Weight Matrices (PWMs) for specific TFs, resolving gene symbols to JASPAR Matrix IDs, or getting TF metadata. Supports multiple output formats (MEME, TRANSFAC, PFM, JASPAR, YAML).

日本語の概要は準備中です。原文の説明を表示しています。

Visualize, analyze, and render protein and molecular structures using PyMOL. Use when the user wants to create images of protein structures, perform structural alignments or superposition, measure distances or contacts, highlight binding sites or active site residues, color by B-factor/pLDDT, or analyze protein-ligand interactions. Do not use for docking, molecular dynamics, or sequence-only analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Predict TCR-epitope specificity using ERGO-II and deep learning models for T-cell receptor antigen recognition. Match TCRs to their cognate epitopes or predict TCR targets. Use when analyzing TCR repertoire specificity or identifying antigen-reactive T-cells.

日本語の概要は準備中です。原文の説明を表示しています。

Predict B-cell and T-cell epitopes using BepiPred, IEDB tools, and structure-based methods for vaccine and antibody design. Identify immunogenic regions in antigens. Use when designing vaccines, mapping antibody binding sites, or predicting immunogenic peptides.

日本語の概要は準備中です。原文の説明を表示しています。

Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features. Rank candidates for vaccine design. Use when prioritizing epitopes for vaccine development or identifying the most immunogenic neoantigens.

日本語の概要は準備中です。原文の説明を表示しています。

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

日本語の概要は準備中です。原文の説明を表示しています。

De novo motif discovery and known motif enrichment analysis using HOMER and MEME-ChIP. Identify transcription factor binding motifs in ChIP-seq, ATAC-seq, or other genomic peak data. Use when finding enriched DNA motifs in peak sequences.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies super-enhancers from H3K27ac ChIP-seq data using ROSE and related tools. Use when studying cell identity genes, cancer-associated regulatory elements, or master transcription factor binding regions that cluster into large enhancer domains.

日本語の概要は準備中です。原文の説明を表示しています。

Guide for working in the grails-data-hibernate7 module, especially Hibernate 7 domain binding, mapping migration, generators, and integration tests. Use this when changing code or tests under grails-data-hibernate7.

日本語の概要は準備中です。原文の説明を表示しています。

Diagnose whether a Codex Desktop update changed codexhost Composer/CDP bindings, private Renderer DOM or React state, Host bridges, routing, the Codex usage submission gate, or injected UI. Use after an installed Codex update or when compatibility regresses and the affected surface is unknown.

日本語の概要は準備中です。原文の説明を表示しています。