「compound」の検索結果

Use when designing or changing a component's public API, its composition, or its state model in libs/ui-react or libs/ui-rnative — layering (core vs internal vs primitives), BaseProps/Props splits, converting a component to compound / changing its composition with createSafeContext, controlled/uncontrolled state, prop-naming conventions, and cross-platform API parity. Load this before shaping a new component, changing its props, or refactoring its composition.

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Capture learnings from a campaign, launch, sprint, or initiative using Five Whys (Taiichi Ohno, Toyota Production System) for root cause analysis and Start-Stop-Continue for action planning. Append reusable insights to knowledge/learnings.md so future runs of the OS get smarter. Use when the user asks for a retro, retrospective, post-mortem, "what did we learn", "campaign wrap-up", "lessons learned", or after a campaign or launch ends. Critical feedback loop that makes the OS compound over time. For the numbers review itself, see kpi-review. For planning the next campaign, see campaign-brief.

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Use when a task needs the judgment of a Drilling and Boring Machine Tool Setter, Operator, or Tender — deciding whether a hole's depth-to-diameter ratio requires peck drilling, establishing a straight hole start before wander compounds, reducing cutting parameters for a long-reach boring setup versus a short-reach one, or diagnosing whether a dimensional drift traces to tool wear rather than assuming the tool still looks sharp.

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Set up an end-to-end test suite in any repo, following practices that make e2e a reliable per-PR gate: real flows over bypass, layered assertions, a reusable auth/session helper, video+trace evidence, and a compounding suite. Use when a repo has no e2e (or weak e2e) and you want system-level tests — "set up e2e", "add end-to-end tests", "scaffold a test gate".

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Use when writing, auditing, or troubleshooting Salesforce Validation Rules. Triggers: 'validation rule', 'required field formula', 'rule fires unexpectedly', 'integration failing validation', 'data quality', 'errorConditionFormula', 'errorDisplayField', 'errorMessage 255 characters', 'ValidationRule metadata', 'validationRule-meta.xml', 'deploy validation rule inactive', 'bypass custom permission', 'FIELD_CUSTOM_VALIDATION_EXCEPTION', 'validation rule on custom metadata type', 'compound field validation rule', 'require at least one child record before a stage', 'HasOpportunityLineItem'. NOT for Flow-based validation — use admin/flow-for-admins for that.

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React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

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Aggregate friction log files across a time period to identify recurring patterns, classify each cluster by intervention type, produce a prioritized action plan with success criteria, and calculate convergence metrics. Complements `skmtc-retro` (which captures per-session signal) by acting as the system's actuator: turning accumulated observations into decisions. The primary output is a review document that makes the "is it getting better?" question answerable. Use this skill when the user asks to "review retros", "review friction", "run a retro review", "what's the pattern across sessions", "what should we fix next", or on a periodic cadence (monthly, pre-release). Also run after a cluster of sessions on the same feature area to surface systemic issues before they compound. Distinct from `skmtc-retro` — that skill captures per-session observations; this skill synthesizes them into decisions. Do not run this skill as a substitute for a per-session retro.

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React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

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Multi-file hypothesis testing with keep/discard loop, compound baselines, and experiment logging

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Persistent cross-session knowledge base. Manages per-project learnings that compound across sessions — patterns, pitfalls, preferences, and project quirks. The agent gets smarter on your codebase over time. At session start, searches relevant learnings. During sessions, logs discoveries. Supports review, search, prune, and export. Use proactively when the agent encounters a durable project quirk, user preference, or pattern that would save 5+ minutes next time. Also use at session start to recover context. Triggers: "remember this", "log this", "what have we learned?", "show learnings".

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Reddit automation skill collection. Supports authentication, content publishing, search & discovery, social interactions, and compound operations. Triggered when a user asks to operate Reddit (post, search, comment, login, analyze, upvote, save).

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Reddit compound content operations skill. Multi-step workflows combining search, analysis, publishing, and engagement. Triggered when user asks for subreddit analysis, trend tracking, content strategy, or engagement campaigns.

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Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven ranking (Exomiser, Phen2Gene, AMELIE), ClinGen gene-disease validity gating, and ACMG SF v3.2 secondary findings reporting. Use when running diagnostic exome / genome pipelines, identifying candidate Mendelian disease genes, screening for incidental findings, or auditing VUS reclassification cycles. The ACMG/AMP classification framework (PVS1 decision tree, Pejaver PP3/BP4 calibration, Tavtigian point system) is in clinical-databases/acmg-classification.

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Queries PharmGKB / CPIC / DPWG for drug-gene interactions; calls CYP2D6/CYP2C9/CYP2C19/DPYD/TPMT/NUDT15/UGT1A1/SLCO1B1 star alleles and phenotype with PharmCAT, Cyrius (CYP2D6 structural variants), Aldy, Stargazer; applies Caudle 2020 activity-score translation. Use when implementing pharmacogenomic-guided prescribing, applying CPIC vs DPWG guidance, screening HLA risk alleles for ICI / antiepileptics / abacavir, or interpreting compound TPMT+NUDT15 thiopurine risk.

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Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.

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Predicts ADMET properties using ADMETlab 3.0 (119 platform features, including 77 prediction models with modeled-endpoint uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.

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Expert-level medicinal chemistry knowledge. Use when working with drug design, structure-activity relationships, ADMET properties, pharmacophores, lead optimization, target identification, drug metabolism, or pharmaceutical development. Also use when the user mentions 'SAR', 'drug design', 'pharmacophore', 'ADMET', 'lead compound', 'hit to lead', 'drug metabolism', 'bioavailability', 'selectivity', 'binding affinity', 'scaffold hopping', or 'bioisostere'.

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React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

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Use when an agent needs to drive a real Chrome window via opencli — inspect a page, fill forms, click through logged-in flows, or extract data ad-hoc. Covers the selector-first target contract, compound form fields, stale-ref handling, network capture, and the agent-native envelopes the CLI returns. Not for writing adapters — see opencli-adapter-author for that.

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Patterns for scaling read-heavy Convex apps to millions of users. Use when optimizing bandwidth, reducing query costs, fixing slow queries, creating digest tables, replacing reactive subscriptions with one-shot fetches, adding compound indexes, debouncing writes, rate-controlling backfills, or running npx convex insights. Trigger when users mention "scale", "bandwidth", "performance", "optimize", "slow queries", "expensive queries", "digest table", "denormalize", or "thundering herd" in the context of Convex.

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Patterns for scaling read-heavy Convex apps to millions of users. Use when optimizing bandwidth, reducing query costs, fixing slow queries, creating digest tables, replacing reactive subscriptions with one-shot fetches, adding compound indexes, debouncing writes, rate-controlling backfills, or running npx convex insights. Trigger when users mention "scale", "bandwidth", "performance", "optimize", "slow queries", "expensive queries", "digest table", "denormalize", or "thundering herd" in the context of Convex.

日本語の概要は準備中です。原文の説明を表示しています。

React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

日本語の概要は準備中です。原文の説明を表示しています。

React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

日本語の概要は準備中です。原文の説明を表示しています。

15-minute daily taste exercises. Monday through Friday. Compound effect over time. Use when building personal practice habits, training a team's design eye, or adding structure to professional development.

日本語の概要は準備中です。原文の説明を表示しています。