677 件 ・ 関連度順
概要と使いどころ
Decompose genetic effects into direct and indirect paths through mediating variables using the mediation R package. Tests whether gene expression, methylation, or other molecular phenotypes mediate the effect of genetic variants on disease. Use when testing whether a molecular phenotype mediates the genotype-to-phenotype relationship.
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Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.
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Detect structural macro regime transitions (1-2 year horizon) using cross-asset ratio analysis. Analyze RSP/SPY concentration, yield curve, credit conditions, size factor, equity-bond relationship, and sector rotation to identify regime shifts between Concentration, Broadening, Contraction, Inflationary, and Transitional states. Run when user asks about macro regime, market regime change, structural rotation, or long-term market positioning.
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Use when the user asks to "build a media list for my launch", "write a launch press release", or "pitch press under embargo"; produces a three-tier media and analyst list (Tier 1 exclusive candidates, Tier 2 vertical press, Tier 3 communities and newsletters), an embargo pitch timing skeleton keyed to the launch-registry date, a press-release draft in standard structure with no fabricated quotes or numbers, and an analyst briefing outline. Not for press-kit assets — use launch-asset-packager; not for follow-up sequence mechanics — use outreach-manager; not for post-launch news-echo monitoring — use launch-monitor. 媒体名单/禁运期pitch/新闻稿/分析师简报
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Use when the user asks to "run my launch day", "build a launch day runbook / war room", or "decide CONTINUE or ROLLBACK after the push"; produces a pre-conditions gate check (launch-readiness-auditor SHIP verdict + the authoritative date in launch-registry — missing either stops the skill), a dated hour-blocked runbook with owners (morning irreversible pushes, daytime monitoring loop, evening consolidation), a forced observation-window verdict after every irreversible action against pre-declared kill criteria, a P0-P3 incident ladder with rollback playbooks, and T-0 status lines for the registry proposal protocol. Not for channel submission content and platform rules — use community-launch-runner; not for media replies — use press-media-relations. 发布日runbook/作战室/观察窗/回滚裁决/发布日指挥
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Use when the user asks to "write influencer outreach", "follow up with a creator", "pitch a journalist, hunter, or launch partner", or "negotiate partnership terms"; produces personalized pitches, multi-touch follow-up sequences, negotiation scripts with objection handling, and a status pipeline tracker — the shared outreach mechanics engine for creator, media/analyst, launch-partner, and social-selling / advocate-recruitment targets. Not for finalizing signed agreements — use contract-helper; not for media-list tiering, embargo terms, or press-release structure — use press-media-relations. 达人邀约建联/合作谈判话术
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Apply the Law of Similarity — shared colour, shape, or size signals that elements belong to one category. Use when signalling relationships across distance. For grouping by position, use `law-of-proximity`.
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Create a modular type scale with size, weight, and line-height relationships. Use when establishing typographic structure. For line length only use `readable-measure`; for judging type on an existing screen use `critique-typography` (visual-critique).
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Map the full ecosystem of touchpoints, channels, and relationships across a service. Use when the experience spans more than one product. For one persona's linear journey use `journey-map` (design-research); for backstage operations use `service-blueprint`.
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Provides authoritative guidance on Amazon Neptune Database and Neptune Analytics for graph, knowledge-graph, and relationship-heavy workloads — fraud detection / fraud rings, agentic memory / chatbot context across sessions, recommendations, identity resolution, Gremlin / openCypher / SPARQL queries, supernode / slow traversal, Neo4j to Neptune migration / APOC compatibility, Neptune Database vs Analytics engine selection, PageRank / community detection, GraphRAG, and connectivity from Lambda / EC2 / applications. Creates and modifies Neptune Database clusters/instances and Neptune Analytics graphs on explicit user confirmation; blocks destructive operations (delete, reset-graph, failover, major upgrade) and redirects to change-control.
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Comprehensive guide for creating software diagrams using Mermaid syntax. Use when users need to create, visualize, or document software through diagrams including class diagrams (domain modeling, object-oriented design), sequence diagrams (application flows, API interactions, code execution), flowcharts (processes, algorithms, user journeys), entity relationship diagrams (database schemas), C4 architecture diagrams (system context, containers, components), state diagrams, git graphs, pie charts, gantt charts, or any other diagram type. Triggers include requests to "diagram", "visualize", "model", "map out", "show the flow", or when explaining system architecture, database design, code structure, or user/application flows.
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Owns the organization itself: org design, hiring, performance, compensation, development, culture, and employee relations. Use this to design or restructure a team, plan hiring, write a role or leveling definition, handle a performance or compensation question, diagnose why a team is underperforming for non-technical reasons, or assess the people risk in a plan. Also use for onboarding design and retention of key staff.
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Handles the difficult human situations — grievances, complaints, investigations, conflict, and separations conducted properly. Use this to respond to a complaint or grievance, structure an investigation, handle a conflict between colleagues, prepare for a difficult conversation, or work out what a manager can and cannot do in a given situation.
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Plans and executes earned media — press strategy, journalist outreach, announcements, commentary, and crisis response. Use this to plan a press push, write a pitch or release, find and approach the right journalists, prepare for an interview, decide whether something is newsworthy, or respond to a story going badly.
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Takes a new customer from signature to working — setting a definition of live that both sides agreed before the contract was signed, planning and staffing the implementation, running data migration and integration realistically, training the people who will actually use it, and handing over to the ongoing relationship. Use this to design an onboarding motion, rescue a stalled implementation, work out why customers who bought never went live, or scope the services a deal actually needs.
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Runs the ongoing relationship with accounts after the sale — segmenting coverage against account value, building a health score that predicts rather than describes, running reviews customers find worth attending, forecasting renewals honestly, and finding expansion that follows usage instead of quota. Use this to design a customer success motion, decide who gets a named contact, work out why renewals surprise you, or fix a health score everyone ignores.
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Structures partnerships that change what the business can do — technology integrations, channel and reseller arrangements, joint ventures, and OEM relationships. Use this to evaluate or structure a strategic partnership, decide between partnering and building, negotiate commercial terms of an alliance, or diagnose a partnership that is signed but not producing. For audience-borrowing partnerships, use `marketing:partnership-marketing`.
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Owns the customer's experience after the sale — support, success, escalation, and the feedback loop back into product. Use this for a decision spanning support and product, when service quality and cost are in tension, when deciding what to staff or automate, when a customer relationship is at risk above the account-manager level, or when nobody owns a recurring customer problem.
日本語の概要は準備中です。原文の説明を表示しています。
Generate radial plots (Radial Plot/Galbraith Plot) for heterogeneity analysis. Visually assess heterogeneity across studies by displaying the relationship between standardized effect sizes and precision. Input: Meta-analysis data in CSV format; Output: Radial plot PNG and data CSV.
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Gregor Mendel — genetics mentor, patient experimenter, and gardener-monk. Trigger this skill when users ask about genetics, heredity, inheritance patterns, Mendelian laws, dominant/recessive traits, gene segregation, independent assortment, Punnett squares, classical genetics, or evolution-genetics connections. Also trigger when discussing the philosophy of science, how great ideas get ignored, the relationship between faith and science, or the virtue of patient long-term observation. Even if the user doesn't say "Mendel" explicitly, trigger this skill for questions touching genetics, breeding, trait inheritance, or genomics history. Part of the AIPOCH Science Mentor Skill Hub.
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Use when evaluating A-share short-term technical setups through Tang Nengtong's classic TA lens: volume-price relationships, moving average systems, breakout signals, and short-term momentum entry/exit.
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Use this skill for any PostgreSQL database work — table design, indexing, data types, constraints, extensions (pgvector, PostGIS, TimescaleDB), search, and migrations. **Trigger when user asks to:** - Explore an existing PostgreSQL database to understand its objects and relationships - Design or modify PostgreSQL tables, schemas, or data models - Choose data types, constraints, indexes, or partitioning strategies - Work with pgvector embeddings, semantic search, or RAG - Set up full-text search, hybrid search, or BM25 ranking - Use PostGIS for spatial/geographic data - Set up TimescaleDB hypertables for time-series data - Migrate tables to hypertables or evaluate migration candidates - Plan or execute safe schema migrations with zero downtime **Keywords:** PostgreSQL, Postgres, SQL, schema, table design, indexes, constraints, pgvector, PostGIS, TimescaleDB, hypertable, semantic search, hybrid search, BM25, time-series, migration
日本語の概要は準備中です。原文の説明を表示しています。
Recover missing spreadsheet values from row and column totals, percentage shares, year-over-year changes, CAGR relationships, and cross-sheet constraints.
日本語の概要は準備中です。原文の説明を表示しています。
Parse SQLite databases into structured JSON data. Use when exploring unknown database schemas, understanding table relationships, and extracting map data as JSON.
日本語の概要は準備中です。原文の説明を表示しています。