「with」の検索結果

Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeCK (multi-screen joint analysis, libraries with broad efficacy variance) and when it does not (single screen, novel libraries with no prior efficacy), library-reuse efficacy transfer, downstream essentiality interpretation, and the 2.5x sample-size reduction enabled by efficacy-aware testing. Use when running multiple screens with the same library, when guide-level noise is suspected to dominate per-gene signal, when reusing published essentiality reference screens for efficacy priors, or when comparing screens performed across cell lines that share library but differ biologically.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Colic et al. 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving greater sensitivity to small-effect hits than MAGeCK / STARS / edgeR / RIGER on drug screens, per-gene sumZ and normZ, synth (sensitizer) vs supp (suppressor) FDR, multi-dose handling, integration with control sgRNAs, and comparison with MAGeCK MLE with dose covariate. Use when running a drug-modifier CRISPR screen, identifying sensitizing or resistance genes for a drug candidate, choosing drugZ vs MAGeCK MLE for chemogenomic analysis, troubleshooting low-effect drug screens where MAGeCK lacks sensitivity, or designing a drug-screen layout (vehicle vs drug arms).

日本語の概要は準備中です。原文の説明を表示しています。

Implement iOS authentication flows with AuthenticationServices and LocalAuthentication. Use when building Sign in with Apple, passkey/WebAuthn registration or sign-in with ASAuthorizationPlatformPublicKeyCredentialProvider, ASAuthorizationController credential state and revocation handling, ASWebAuthenticationSession OAuth or third-party login, Password AutoFill, identity-token server validation, or local biometric re-authentication with LAContext.

日本語の概要は準備中です。原文の説明を表示しています。

Build direct Bluetooth Low Energy workflows with Core Bluetooth. Use when implementing BLE central or peripheral GATT communication, scanning or connecting with CBCentralManager, discovering services and characteristics, reading/writing/subscribing with CBPeripheral, publishing local services with CBPeripheralManager, handling Bluetooth authorization, background BLE modes, state restoration, write flow control, or CBUUID-based workflows. For privacy-preserving accessory setup/picker flows, use accessorysetupkit first and return here for post-setup GATT communication.

日本語の概要は準備中です。原文の説明を表示しています。

Use DuckDB from MATLAB via Database Toolbox (R2026a+) as a non-math operations engine on large tabular files (CSV/Parquet/JSON) and as a zero-config embedded database. Use when connecting to DuckDB, querying CSV, Parquet, and JSON files directly with SQL, reducing or profiling large data before MATLAB analysis, creating portable development databases, or installing DuckDB extensions. Triggers on: DuckDB, duckdb(), large CSV/Parquet/JSON, file too large for readtable, filter/aggregate at source, deduplicate, reduce before analysis, profile large file, persistent file import, analytical engine, SQL on CSV, SQL on Parquet, SQL on JSON, query CSV with SQL, query Parquet with SQL, run SQL on files, SQL queries on files, query files directly, SQL without database, in-process SQL.

日本語の概要は準備中です。原文の説明を表示しています。

State machine-based vector animation with runtime interactivity and web integration. Use this skill when creating interactive animations, state-driven UI, animated components with logic, or designer-created animations with runtime control. Triggers on tasks involving Rive, state machines, interactive vector animations, animation with input handling, ViewModel data binding, or React Rive integration. Alternative to Lottie for animations requiring state machines and two-way interactivity.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze current trends and challenges in Japanese NLP for a topic. Surveys the existing awesome-japanese-nlp-resources dataset and augments it with up-to-the-minute web research to produce a combined trend + issue report. Use only when the user explicitly wants a trend/landscape report, a challenges/limitations report, or a general research overview of a Japanese NLP topic (this combines the bundled dataset with live web research). Trigger phrases include '日本語LLMの最新トレンド', '〜の動向をまとめて', '最近の日本語NLPの流れ', '日本語LLMの課題', '〜の問題点・限界', '未解決の論点', 'trend report on Japanese embeddings', 'latest Japanese speech models', 'challenges in Japanese NER', 'limitations of Japanese embeddings'. For a simple lookup use the search skill; this one runs web research.

Force-links a development or target environment to a Power Platform Pipelines host, overriding any existing association with a previous host. Use when creating a deploymentenvironments record fails with "this environment is already associated with another pipelines host", or when intentionally migrating an environment from one host to another (e.g., Platform Host → Custom Host, or between two Custom Hosts). Calls the documented `ManageEnvironmentStamp` Dataverse action (the API behind the "Force Link" button in the Deployment Pipeline Configuration app). DESTRUCTIVE to the previous host: makers lose access to any pipelines in that host that used this environment. Reversible by running Force Link from the previous host. Use when asked to: "force link environment", "force-link to new host", "switch pipelines host", "environment already associated with another host", "take over pipelines association", "relink environment to host".

日本語の概要は準備中です。原文の説明を表示しています。

Use when retexturing an existing 3D asset with PATINA PBR materials through the Scenario MCP server: a GLB or Blender scene (an image-to-3D result with flat colors, a prop, a diorama) whose surfaces need basecolor, normal, roughness, metalness, and height maps per material family with geometry untouched, or a matched before-and-after comparison film rendered in Blender with one camera path, lighting, and cut. Keywords: PATINA, PBR retexture, material families, Blender EEVEE, comparison video.

日本語の概要は準備中です。原文の説明を表示しています。

Build resilient, long-running, multi-step applications with AWS Lambda durable functions with automatic state persistence, retry logic, and orchestration for long-running executions. Covers the critical replay model, step operations, wait/callback patterns, error handling with saga pattern, testing with LocalDurableTestRunner. Triggers on phrases like: lambda durable functions, workflow orchestration, state machines, retry/checkpoint patterns, long-running stateful Lambda functions, saga pattern, human-in-the-loop callbacks, and reliable serverless applications.

日本語の概要は準備中です。原文の説明を表示しています。

Build and deploy full-stack web and mobile apps with AWS Amplify Gen2 (TypeScript code-first). Covers auth (Cognito), data (AppSync/DynamoDB including schema modeling, enum types, relationships, authorization rules), storage (S3), functions, APIs, and AI (Amplify AI Kit with Bedrock). Supports React, Next.js, Vue, Angular, React Native, Flutter, Swift, and Android. Always use this skill for Amplify Gen2 topics — even for questions you think you know — it contains validated, version-specific patterns that prevent common mistakes. TRIGGER when: user mentions Amplify Gen2; project has amplify/ directory or amplify_outputs; code imports @aws-amplify packages; user asks about defineBackend, defineAuth, defineData, defineStorage, or npx ampx. SKIP: Amplify Gen1 (amplify CLI v6), standalone SAM/CDK without Amplify (use aws-serverless), direct Bedrock without Amplify AI Kit (use bedrock).

日本語の概要は準備中です。原文の説明を表示しています。

Terraform provider acceptance test patterns using terraform-plugin-testing with the Plugin Framework. Covers test structure, TestCase/TestStep fields, ConfigStateChecks with custom statecheck.StateCheck implementations, plan checks, CompareValue for cross-step assertions, config helpers, import testing with ImportStateKind, sweepers, and scenario patterns (basic, update, disappears, validation, regression), and ephemeral resource testing with the echoprovider package. Use when writing, reviewing, or debugging provider acceptance tests, including questions about statecheck, plancheck, TestCheckFunc, CheckDestroy, ExpectError, import state verification, ephemeral resources, or how to structure test files.

日本語の概要は準備中です。原文の説明を表示しています。

Writes a settlement letter on the right footing — and warns you when marking it 'without prejudice' won't actually keep it out of court. A genuine settlement letter is normally protected (the judge can't see it), but only if the substance is a real attempt to settle, and even then there are exceptions. The skill picks the correct footing — without prejudice (WP), without prejudice save as to costs (WPSATC / Calderbank), or open — drafts the finished letter, and surfaces the Unilever v Procter & Gamble exceptions that get WP material admitted despite the label, which a plain template won't flag. Built for juniors and in-house counsel drafting a settlement or Calderbank offer who need the footing right the first time. Use when the user asks to draft a WP letter, a Calderbank, a settlement letter, or wants to know whether material is likely protected from disclosure.

日本語の概要は準備中です。原文の説明を表示しています。

Design a single-point rubric with one criterion and open columns for evidence. Use for student self-assessment, peer feedback, teacher formative feedback, or pre-task planning. Works with any learning target, with or without a band system.

日本語の概要は準備中です。原文の説明を表示しています。

The package CellBarcode performs Cellular DNA Barcode analysis. It can handle all kinds of DNA barcodes, as long as the barcode is within a single sequencing read and has a pattern that can be matched by a regular expression. \code{CellBarcode} can handle barcodes with flexible lengths, with or without UMI (unique molecular identifier). This tool also can be used for pre-processing some amplicon data such as CRISPR gRNA screening, immune repertoire sequencing, and metagenome data.

日本語の概要は準備中です。原文の説明を表示しています。

Build AI applications with OpenAI Agents SDK - text agents, voice agents, multi-agent handoffs, tools with Zod schemas, guardrails, and streaming. Prevents 11 documented errors. Use when: building agents with tools, voice agents with WebRTC, multi-agent workflows, or troubleshooting MaxTurnsExceededError, tool call failures, reasoning defaults, JSON output leaks.

日本語の概要は準備中です。原文の説明を表示しています。

Comprehensive R package for command-line interface styling, semantic messaging, and user communication. Use this skill when working with R code that needs to: (1) Format console output with inline markup and colors, (2) Display errors, warnings, or messages with cli_abort/cli_warn/cli_inform, (3) Show progress indicators for long-running operations, (4) Create semantic CLI elements (headers, lists, alerts, code blocks), (5) Apply themes and customize output styling, (6) Handle pluralization in user-facing text, (7) Work with ANSI strings, hyperlinks, or custom containers. Also use when migrating from base R message/warning/stop, debugging cli code, or improving existing cli usage.

日本語の概要は準備中です。原文の説明を表示しています。

Run file-based C# apps with the .NET CLI when the user explicitly wants C#/.NET code without creating a project. Use for C# language/API experiments, one-file C# apps, small multi-file C# apps composed with `#:include`/`#:exclude`, or C# file-based apps linked with `#:ref`. Do not use for language-agnostic throwaway scripts, generic computations, Python/PowerShell-style automation, full projects, or existing app integration.

日本語の概要は準備中です。原文の説明を表示しています。

Guides technology selection and implementation of AI and ML features in .NET 8+ applications using ML.NET, Microsoft.Extensions.AI (MEAI), Microsoft Agent Framework (MAF), GitHub Copilot SDK, ONNX Runtime, and OllamaSharp. Covers the full spectrum from classic ML through modern LLM orchestration to local inference. Use when adding classification, regression, clustering, anomaly detection, recommendation, LLM integration (text generation, summarization, reasoning), RAG pipelines with vector search, agentic workflows with tool calling, Copilot extensions, or custom model inference via ONNX Runtime to a .NET project. DO NOT USE FOR projects targeting .NET Framework (requires .NET 8+), the task is pure data engineering or ETL with no ML/AI component, or the project needs a custom deep learning training loop (use Python with PyTorch/TensorFlow, then export to ONNX for .NET inference).

日本語の概要は準備中です。原文の説明を表示しています。

Plan complex Blazor UI features by decomposing them into focused components. USE FOR: building a complex Blazor page with multiple sections, planning component decomposition, designing a multi-section dashboard or layout, breaking down a large UI feature into composable components, pages with sidebars and content panels, any page with 3+ distinct visual sections or multiple interacting sub-features, identifying parent-child relationships and data flow. DO NOT USE FOR: creating new Blazor projects or apps from scratch (use create-blazor-project), implementing a single individual component (use author-component), writing component code with parameters and EventCallback (use author-component), or simple single-component pages.

日本語の概要は準備中です。原文の説明を表示しています。

Resizes, scales, and adjusts video resolution and dimensions using GPU-accelerated NVENC encoding via Volcengine LAS. Video resizing, video scaling, video upscaling, and video downscaling — change video resolution, enlarge or shrink video dimensions, and adjust video size for different platforms and screens. Video compression by reducing resolution and video transcoding and re-encoding with specific dimension constraints. Supports flexible min/max width and height ranges with aspect ratio preservation strategies (increase, decrease, or disable), including landscape to portrait conversion. Async submit-poll workflow with batch support. Use this skill when the user wants to resize or scale video resolution (upscale/downscale), change video dimensions for different platforms, compress videos by reducing resolution, transcode/re-encode videos with GPU NVENC, adjust aspect ratio including landscape-to-portrait conversion, adapt videos for mobile/web/social media, or batch process multiple videos.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks for "deep research", "research team", "comprehensive analysis", "research report", "investigate thoroughly", "compare X vs Y in depth", or needs synthesis across multiple sources with verification. It spawns a coordinated team of researcher agents across multiple rounds, with the lead triaging findings and creating targeted follow-up tasks. Scales from Focused (2 researchers, 1-2 rounds) to Comprehensive (4 researchers, 3-4 rounds with cross-verification). Do NOT use for simple lookups, debugging, or questions answerable with 1-2 searches.

日本語の概要は準備中です。原文の説明を表示しています。

Use when you need to set up Java application profiling to detect and measure performance issues — including trusted preinstalled async-profiler v4.x setup, problem-driven profiling (CPU, memory, threading, GC, I/O), interactive profiling scripts, JFR integration with Java 25 (JEP 518, JEP 520), or collecting profiling data with flamegraphs and JFR recordings. This should trigger for requests such as Improve the code with profiling; Apply Profiling; Refactor the code with profiling; Add profiling support; Collect JFR or async-profiler data for Java performance. Part of Plinth Toolkit

日本語の概要は準備中です。原文の説明を表示しています。

Use when you need to write unit tests for Spring Boot applications — including pure unit tests with @ExtendWith(MockitoExtension.class) for @Service/@Component, slice tests with @WebMvcTest and @MockitoBean for controllers, @JsonTest for JSON serialization, parameterized tests with @CsvSource/@MethodSource, test profiles, and @TestConfiguration. For framework-agnostic Java use @131-java-testing-unit-testing. For integration tests use @322-frameworks-spring-boot-testing-integration-tests. This should trigger for requests such as Review Java code for Spring Boot unit tests; Apply best practices for Spring Boot unit tests in Java code; Write Mockito-first unit tests for Spring Boot services; Avoid unnecessary @SpringBootTest in Spring unit tests; Review Spring Boot slice-free unit test design. Part of Plinth Toolkit

日本語の概要は準備中です。原文の説明を表示しています。