「sse」の検索結果

Chemical safety and toxicology assessment integrating ADMET-AI predictions, CTD toxicogenomics, PubChemTox experimental data, GHS/IARC hazard classification, and exposure-context analysis. Use for chemical hazard identification, occupational/consumer-product toxicity, dose-response evaluation, and acute (LD50) vs chronic toxicity assessment. Distinguishes drug toxicity from environmental chemical toxicity.

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Analyze the competitive landscape for an SCF submission. Identifies similar projects on Stellar and other chains, assesses overlap and differentiation. Use when reviewing or drafting an SCF submission and you need to map similar projects on Stellar and other chains and articulate the differentiation.

日本語の概要は準備中です。原文の説明を表示しています。

Create, migrate, improve, or debug detailed vehicle assets for CARLA using Blender and Unreal, including reference-based geometry, materials, wheels, physics, lights, and runtime validation. Use for vehicle asset authoring rather than ordinary traffic spawning or map decoration.

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Imports an FBX vehicle into a CARLA source build as a spawnable vehicle.<make>.<model> — checks the FBX carries CARLA's 4-wheel bone rig, imports the mesh, then assembles the vehicle through CarlaTools' VehicleAuthoringLibrary (physics asset with kinematic wheel bodies, retargeted anim blueprint, four configured wheel blueprints, the vehicle blueprint), registers it in VehicleFactory through CARLA's own add_vehicle_to_vehicle_factory.py, and verifies it spawns, drives and steers. Use when the user asks to "add a car/truck/van to CARLA", "import a vehicle FBX", or needs a custom drivable vehicle spawnable from the Python API.

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Echo (LabStack) v5 — Go Web framework リファレンス。routing（Group）、echo.Context、 Bind、Validator、HTTPError、HTTPErrorHandler、RFC 9457 Problem Details、 middleware（JWT, CORS, CSRF, BasicAuth, Gzip, Recover, Logger, RateLimiter）、 OpenTelemetry (echo-otel)、IPExtractor、SchemeExtractor、Renderer、WebSocket、SSE、 AutoTLS 実装例。

Rust 製バックエンド HTTP サーバーフレームワーク fandhe-backend のリファレンス。 fandhe-backend-core / -http / -routes。Server, BoundServer, Router（merge）, Handler。 拡張点 Middleware（on_response_with_status）/ UpgradeHandler / RequestGate / Interceptor。 Diagnostics, StreamingResponse, SetCookie session（__Host-）, sans-IO HTTP/1.1, graceful shutdown。 プラグイン cors, websocket（WsSender）, graphql, openapi, webrtc, jwt（JwtGate, JwtPolicy）, csrf（CsrfGate）。

Android アプリ開発 (Kotlin) のバックグラウンド・非同期処理リファレンス。 Jetpack androidx WorkManager: Worker, CoroutineWorker, WorkRequest, Constraints, WorkInfo, WorkContinuation, expedited work, テスト。 Service: フォアグラウンドサービス, バウンドサービス, AIDL, Messenger。 AlarmManager, PendingIntent, BroadcastReceiver, JobScheduler, Doze。 Kotlin コルーチン, Flow, StateFlow, SharedFlow, Channel。

Android アプリ開発 (Kotlin) のデータ層リファレンス。Jetpack androidx。 Room / Room 3 (androidx.room3) (Entity, Dao, Query, Migration, prepopulate, createFromAsset), DataStore (Preferences/Proto, Direct Boot), MediaStore, SharedPreferences, スコープ付きストレージ, Retrofit, OkHttp。

Claude Managed Agents (platform.claude.com) リファレンス。Agents / Sessions / Environments API, SSE event streaming, event deltas, session threads, session budgets, multiagent orchestration (subagents, dynamic workflows, workflow runs, advisor), deployments (cron), dreams, vaults, memory stores, self-hosted sandboxes, webhooks, web search / fetch ドメイン制限, secure deployment, permission policies, Agent Skills, MCP connector, user profiles。

Claude API (platform.claude.com) の Messages API リファレンス。 streaming (SSE), thinking (adaptive) / preserved thinking / effort, prompt caching, context editing, compaction (on-demand / threshold), structured outputs, Message Batches, token counting, vision / PDF, Files API, citations, embeddings (Voyage AI), errors, rate limits, beta headers, Bedrock / Vertex AI / Foundry 経由アクセス。

AVFoundation / AVKit / PhotoKit リファレンス。 AVPlayer, AVPlayerViewController, VideoPlayer, AVPlayerItem, AVMutableComposition, AVCaptureSession, AVCaptureDevice, AVCapturePhotoOutput, AVCaptureDeviceDirectionCoordinator, CameraCaptureAccessory (iPhone Duo), AVAudioEngine, AVAudioSession, AVAudioPlayer, AVSpeechSynthesizer, PHAsset, PHImageManager, PhotosPicker, PHPhotoLibrary。

App Store Connect API 4.5.1 (REST) アプリ配布リファレンス。JWT 認証、API キー作成・失効、 Apps, Builds, Bundle IDs, Bundle ID Capabilities, Certificates, Devices, Provisioning Profiles, Users, User Invitations, Merchant IDs, Pass Type IDs、TestFlight (Beta Groups / Testers)、 Sandbox Testers、App Review, Review Submissions, Customer Reviews, Custom Product Pages, Phased Release、In-App Purchases, Subscriptions, Subscription Groups, App Price Points, Promotional Offers, Win-back Offers, Sales Reports、App Asset Library (screenshots / app previews)、 Webhooks / Webhook Events / Deliveries、Xcode Cloud (Workflows, Build Runs, Artifacts)、 Alternative Distribution (EU マーケットプレイス / Web Distribution)、 Game Center (Achievements, Leaderboards, Challenges)、Analytics / 診断レポート。

CadQuery (Python 製 3D CAD スクリプティングライブラリ) リファレンス。 Workplane API (lineTo / extrude / revolve / sweep / loft / fillet / chamfer / shell)、 Sketch API、Assemblies (Constraint solver)、Free Function API (hollow / prism / draft / offset2D, History)、 Selectors、Shape / Vertex / Edge / Wire / Face / Shell / Solid、 Import / Export (STEP / DXF / STL / glTF / SVG)、Visualization (VTK, cadquery.fig 非ブロッキング, Jupyter)、CQGI。

Analyze a paper draft objectively and strictly. Identifies logic gaps, missing proofs, structural issues, and research weaknesses. Reviewer mode. Use for "analyze this paper", "find weaknesses in draft". 旧名 review-analyze。

日本語の概要は準備中です。原文の説明を表示しています。

Plan and report authorized vulnerability assessments on owned systems. Prioritize evidence, severity, and remediations. Do not deliver exploit payloads.

日本語の概要は準備中です。原文の説明を表示しています。

Transfers gene annotations between genome assemblies via coordinate liftover (UCSC liftOver, CrossMap for same-species version updates) or feature/sequence projection (Liftoff for same/close species, miniprot for protein-level cross-species, TOGA/GeMoMa/CAT for distant clades). Covers the coordinate-vs-projection decision by divergence, why a successful lift is not biological confirmation, reference bias, the silent-dropping of unmapped features, build/PAR/MHC/inversion hazards, and transfer-vs-de-novo validation. Use when annotating a new assembly of a species with an existing reference, harmonizing coordinates across builds, or mapping annotations across related species.

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Assesses genetic health of populations for conservation with Ne estimation across time horizons (LDNe NeEstimator V2 option-file API + SNeP physical-linkage correction; recent trajectory via GONE/GONE2; deep history via Stairway Plot 2 / dadi / fastsimcoal2 / PSMC), F-statistics, runs of homozygosity binned by length class to date inbreeding, genetic-load decomposition (Bertorelle 2022 realized vs masked), the modern 100/1000 Ne rule (Frankham 2014), Ne/Nc 2-6 orders of magnitude in marine fish (Hauser & Carvalho 2008), tree-sequence forward simulations (SLiM 4 + pyslim + tskit), and the Sukumaran-Knowles caveat against MSC methods for management-unit definition. Use when estimating Ne by time horizon, detecting inbreeding via F_ROH, decomposing genetic load, justifying conservation thresholds, distinguishing ESU/MU/DPS, configuring NeEstimator V2, or correcting LDNe physical linkage.

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Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

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Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the p53-dependent G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

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Comprehensive quality control for CLIP-seq libraries (eCLIP, iCLIP, iCLIP2, PAR-CLIP) covering library complexity (preseq), FRiP, IDR replicate reproducibility, read-distribution metagene, SMInput vs IgG control rationale, rRNA / snoRNA contamination, fragment-length distribution, and ENCODE-compliance thresholds. Use when assessing whether a CLIP library passed, deciding lenient vs stringent peak thresholds, comparing replicates with IDR rescue and self-consistency ratios, or distinguishing failed IP from over-amplified library.

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Build and analyze pangenomes for prokaryotes (Panaroo, PPanGGOLiN, PEPPAN, GET_HOMOLOGUES, anvi'o pangenomics) and eukaryotes (Minigraph-Cactus, PGGB, vg pangenome graphs). Implement Tettelin core/accessory/cloud genome decomposition (Tettelin 2005), Heap's law open/closed pangenome modeling, gene presence/absence GWAS (Scoary, pyseer), pangenome graph variant calling (vg, PanGenie), and structural-variation graph indexing. Use when assembling species- or genus-level pan-gene catalogs, separating core from accessory/shell/cloud genes, testing gene-content associations with phenotypes, building pangenome graphs from haplotype-resolved assemblies, calling SVs from pangenome graphs, or selecting between bacterial-pangenome and eukaryotic-pangenome workflows.

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Constructs and validates polygenic risk scores using LDpred2-auto, SBayesRC, MegaPRS, PRS-CS, PROSPER, MUSSEL, BridgePRS, JointPRS, PRSmix, or PGS Catalog Calculator with ancestry-aware reference panels (HapMap3, UKB-LD), Pejaver-style calibration, and PRS-RS reporting standards. Use when computing PRS for cohorts, applying Whiffin-style absolute-risk transformation, assessing cross-ancestry portability (Martin 2017 / Ding 2023 continuous ancestry), or auditing PRS manuscripts against the 22-item PRS-RS reviewer checklist.

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Align preprocessed CLIP-seq reads (eCLIP, iCLIP, iCLIP2, PAR-CLIP) to genome with STAR or bowtie2 using crosslink-preserving parameters, choosing between unique-mapper-only and multi-mapper-aware alignment for repeat-binding RBPs, deciding STAR vs HISAT2 memory trade-offs, and applying ENCODE-compatible filters. Use when turning preprocessed CLIP FASTQ into a deduplicated, MAPQ-filtered BAM ready for peak calling or crosslink-site detection.

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Assesses ChIP-seq quality across antibody specificity, fragmentation, enrichment, replicate concordance, and library complexity. Computes FRiP, NSC/RSC (phantompeakqualtools), library complexity (NRF/PBC1/PBC2), deepTools plotFingerprint (JS distance, AUC, synthetic JS), ChIPQC, IDR with ENCODE Nself/Nt rules, and detects hyper-ChIPable artifacts. Use when validating an antibody, diagnosing failed peak calls, deciding whether to proceed with downstream analysis, grading against ENCODE thresholds, or auditing replicate concordance.

日本語の概要は準備中です。原文の説明を表示しています。