「tia」の検索結果

Save MultiAssayExperiments to h5mu files supported by muon and mudata. Muon is a Python framework for multimodal omics data analysis. It uses an HDF5-based format for data storage.

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The Bandle package enables the analysis and visualisation of differential localisation experiments using mass-spectrometry data. Experimental methods supported include dynamic LOPIT-DC, hyperLOPIT, Dynamic Organellar Maps, Dynamic PCP. It provides Bioconductor infrastructure to analyse these data.

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R generic interface to Hi-C contact matrices in `.(m)cool`, `.hic` or HiC-Pro derived formats, as well as other Hi-C processed file formats. Contact matrices can be partially parsed using a random access method, allowing a memory-efficient representation of Hi-C data in R. The `HiCExperiment` class stores the Hi-C contacts parsed from local contact matrix files. `HiCExperiment` instances can be further investigated in R using the `HiContacts` analysis package.

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This package builds on existing tools and adds some simple but extremely useful capabilities for working wth ChIP-Seq data. The focus is on detecting differential binding windows/regions. One set of functions focusses on set-operations retaining mcols for GRanges objects, whilst another group of functions are to aid visualisation of results. Coercion to tibble objects is also implemented.

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Harmonize data management of multiple experimental assays performed on an overlapping set of specimens. It provides a familiar Bioconductor user experience by extending concepts from SummarizedExperiment, supporting an open-ended mix of st

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Complex heatmaps are efficient to visualize associations between different sources of data sets and reveal potential patterns. Here the ComplexHeatmap package provides a highly flexible way to arrange multiple heatmaps and supports various

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Provides delayed computation of a matrix of residuals after fitting a linear model to each column of an input matrix. Also supports partial computation of residuals where selected factors are to be preserved in the output matrix. Implements

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Design and build expressive 3D scenes, explainers and interactive models with grounded subject knowledge. Use for 3D creation or edits, including scientific visualization and spatial puzzles.

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Analyze the photograph uploaded by the user, deconstruct its visual evidence, abstract and distill the essential relationships, then reconstruct them as a new nonliteral lower-panel composition guided by 19 bundled references. Use for CLEAN upper-photo/lower-abstraction editorial artworks with a number, date, and short phrase in the lower panel. This is abstraction and reconstruction, never style conversion or a miniature redraw. Preserve the exact user-uploaded photograph unchanged above.

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Automatic code quality and best practices analysis. Use proactively when files are modified, saved, or committed. Analyzes code style, patterns, potential bugs, and security basics. Triggers on file changes, git diff, code edits, quality mentions.

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Detect exposed secrets, API keys, credentials, and tokens in code. Use before commits, on file saves, or when security is mentioned. Prevents accidental secret exposure. Triggers on file changes, git commits, security checks, .env file modifications.

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Wholesale product sourcing — supplier discovery, negotiation, MOQ optimization, margin analysis

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Private label launch playbook — product selection, branding, supplier management, differentiation strategy

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Autonomous cold email campaign launcher. Takes one target company domain, scrapes their website, generates an ICP with Claude, pulls matching leads via Prospeo, enriches emails + company descriptions, personalizes each lead with parallel Claude Code Task sub-agents (A/B/C variants), and uploads as a live Smartlead campaign. Uses local JSON files for state (no database required). Use for automated daily campaign launches after you have an initial `client-profile.yaml` from /icp-onboarding. Triggers on "auto-research", "launch an automated campaign", "daily campaign", "run the research loop".

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Configure or change the approved worker models for codex-on-crack, inspect available models and compatibility, preview role files, or undo a setup. The user selects the lead in Codex. Setup preserves root settings, credentials, unrelated agents, and config.toml.

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Plan and execute substantial multi-file builds, features, migrations, and refactors with Astra as orchestrator and DeepSeek V4.1 Flash as the native Codex implementation worker. Use for phased planning and delegated build execution, including existing Superpowers or GSD plans. Skip trivial edits and explicitly single-agent tasks. Worker children must not invoke this orchestration skill.

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Start a substantial build with Codex on Crack. Inspect the user's own configured models and readiness, recommend a lead/worker/tool shape with reasons, and let the user decide before work starts. Use before delegating; keep small or solo tasks direct.

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Lead substantial Codex builds with one configured implementation worker and lead acceptance. Use when the user requests codex-on-crack, names a model to delegate work to, asks to run subagents through Claude, or requests a lead/worker split. Keep host-only work direct; honor explicit external model choices. Workers must not invoke this orchestrator.

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Maintains a repo-local task forest or task DAG for the current workspace. Use when the user asks to initialize or update a task forest, close a session, summarize evolving project work, align a request with a global goal, track progress/history/deviations/todos, save or apply a task proposal, or export the client-readable task-forest HTML. Do not use for executing the tracked tasks themselves or for generic HTML work.

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Local user-profile maintenance skill for Codex, Claude Code, OpenClaw, OpenCode, and other agent harnesses. Use only when the user explicitly invokes $user-profile-keeper to create, initialize, update, query, correct, delete, export, or audit a local persistent user profile. It can extract durable collaboration preferences, requirement-expression habits, capability boundaries, recurring omissions, risk preferences, privacy boundaries, and typical events from the current session into auditable, confirmable, retractable local profile data. Do not auto-invoke, upload profile data, or replace task-clarifier's normal clarification flow.

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Catch hardcoded secrets, keys, and tokens before they get committed. Use before any commit and on any file with credentials.

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Escalate blocked runs to a human via configured channel or fallback to BLOCKED.md and exit the loop. Use when the loop hits an ambiguous spec, a missing credential, a destructive action needing approval, or 3+ consecutive verify failures on the same task.

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Negotiate a pre-code contract between generator and evaluator personas that defines what "done" means before any code is written. Turns fuzzy specs into a testable target the evaluator can hold the generator to.

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Read git log since initial scaffold + last 3 progress notes, draft feature additions to a SEPARATE suggestions file so feature_list.json stays immutable

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