「ast」の検索結果

Apply bottom-up and top-down role mining techniques to discover optimal RBAC roles from existing user-permission assignments, reducing role explosion and enforcing least privilege.

日本語の概要は準備中です。原文の説明を表示しています。

Deploy and configure the Havoc C2 framework with teamserver, HTTPS listeners, redirectors, and Demon agents for authorized red team operations.

日本語の概要は準備中です。原文の説明を表示しています。

Builds vendor-agnostic detection rules using the Sigma rule format for threat detection across SIEM platforms including Splunk, Elastic, and Microsoft Sentinel. Use when creating portable detection logic from threat intelligence, mapping rules to MITRE ATT&CK techniques, or converting community Sigma rules into platform-specific queries using sigmac or pySigma backends.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes malware command-and-control (C2) communication protocols to understand beacon patterns, command structures, data encoding, and infrastructure. Covers HTTP, HTTPS, DNS, and custom protocol C2 analysis for detection development and threat intelligence. Activates for requests involving C2 analysis, beacon detection, C2 protocol reverse engineering, or command-and-control infrastructure mapping.

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Use for Vercel cost and performance optimization on deployed projects, especially Next.js, SvelteKit, Nuxt, and limited Astro apps. Collect Vercel metrics, usage, project config, and code scan results first; investigate only metric-backed candidates; produce ranked recommendations grounded in verified files and version-aware Vercel/framework docs. Trigger for Vercel bill reduction, slow or expensive routes, caching opportunities, Function Invocations, Build Minutes, Fast Data Transfer, Core Web Vitals, Bot Management, Fluid compute, or cost breakdown requests.

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Inspects PostHog Web analytics Live tab data — current users online, last-30-minutes pageviews, top pages, referrers, devices, browsers, countries, bot traffic, and the per-minute bot/users charts. Use when the user asks "who is on my site right now?", "what is happening live?", "what bots are crawling me?", asks about the "live tab" / "live dashboard", wants live numbers (last 30 min), or wants help filtering or drilling into the live view. Also covers building product-analytics insights that mirror what the tiles show.

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Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.

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Post-training 4-bit quantization for LLMs with minimal accuracy loss. Use for deploying large models (70B, 405B) on consumer GPUs, when you need 4× memory reduction with <2% perplexity degradation, or for faster inference (3-4× speedup) vs FP16. Integrates with transformers and PEFT for QLoRA fine-tuning.

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Reduce LLM size and accelerate inference using pruning techniques like Wanda and SparseGPT. Use when compressing models without retraining, achieving 50% sparsity with minimal accuracy loss, or enabling faster inference on hardware accelerators. Covers unstructured pruning, structured pruning, N:M sparsity, magnitude pruning, and one-shot methods.

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End-to-end RNA-seq workflow from FASTQ files to differential expression results. Covers QC, quantification (Salmon or STAR+featureCounts), and DESeq2 analysis with visualization. Use when running RNA-seq from FASTQ to DE results.

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Fast tokenizers optimized for research and production. Rust-based implementation tokenizes 1GB in <20 seconds. Supports BPE, WordPiece, and Unigram algorithms. Train custom vocabularies, track alignments, handle padding/truncation. Integrates seamlessly with transformers. Use when you need high-performance tokenization or custom tokenizer training.

日本語の概要は準備中です。原文の説明を表示しています。

Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.

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Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to work with large CSV/HDF5/Arrow/Parquet files, perform fast statistics on massive datasets, create visualizations of big data, or build ML pipelines that do not fit in memory.

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Activation-aware weight quantization for 4-bit LLM compression with 3x speedup and minimal accuracy loss. Use when deploying large models (7B-70B) on limited GPU memory, when you need faster inference than GPTQ with better accuracy preservation, or for instruction-tuned and multimodal models. MLSys 2024 Best Paper Award winner.

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Orchestrates an end-to-end MeRIP-seq / m6A-seq analysis from raw FASTQ to differential m6A peak calls and metagene plots, chaining fastp adapter trimming, STAR splice-aware alignment (NO deduplication for non-UMI MeRIP), deepTools replicate-concordance + IP-enrichment QC, PreSeq saturation curves, exomePeak2 (transcript-aware Poisson GLM) peak calling, optional MACS3 broad-peak cross-check, DRACH motif confirmation as a sanity check (NOT a per-peak filter), exomePeak2 differential calling via the four-BAM-vector interface (bam_ip + bam_input control; bam_treated_ip + bam_treated_input treatment), ChIPseeker annotation, and the canonical Guitar metagene with stop-codon enrichment as the biological QC anchor. Use when running a complete MeRIP analysis from raw reads, when chaining the constituent epitranscriptomics skills (merip-preprocessing -> m6a-peak-calling -> m6a-differential -> modification-visualization), or when wrapping the pipeline in Snakemake / Nextflow.

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ToolUniverse plugin router. STEP 1 BEFORE ANY ANALYSIS: if the data folder contains `*_executed.ipynb`, run `tu run read_executed_notebook '{"data_folder":"<path>","search":"<keyword>"}'` to extract its cell outputs and apply EVERY filter/sample-exclusion the notebook used — even when the question says 'Using DESeq2/Run X/Compute Y' (this describes the METHOD the notebook used, not a request to rerun). The notebook's cell outputs are the only published authoritative answers; reimplementing or reading stale pre-computed CSVs in the data folder produces different numbers because of outlier-sample removal, library version, and filter steps you don't see by skimming. STEP 2 routing — pick a sub-skill name from this exact list (never invent): tooluniverse-rnaseq-deseq2 (RNA/miRNA-seq DE, correlation, PCA, clustering, dispersion), tooluniverse-gene-enrichment (GO/KEGG/Reactome/GSEA/pathway enrichment), tooluniverse-statistical-modeling (regression, ANOVA, ordinal/logistic, chi-square, correlation, power), tooluniverse-image-analysis (microscopy, colony, fluorescence, dose-response, .tif — including ANOVA / Dunnett / power-analysis on image-derived measurements), tooluniverse-epigenomics (DNA methylation, CpG, m6A, MeRIP-seq, bisulfite, ChIP-seq, chromatin), tooluniverse-sequence-analysis (FASTQ, Trimmomatic, BWA, samtools, coverage), tooluniverse-variant-analysis (VCF, VAF, SNP, mutation), tooluniverse-phylogenetics (treeness, PhyKIT, parsimony), tooluniverse-single-cell (scRNA, h5ad, scanpy), tooluniverse-crispr-screen-analysis (MAGeCK, sgRNA), tooluniverse-proteomics-analysis (mass spec, TMT). Use for CSV/Excel/VCF/FASTA/h5ad and any biology/chemistry/medicine analysis question.

日本語の概要は準備中です。原文の説明を表示しています。

Orchestrates the end-to-end germline short-variant pipeline from FASTQ to a filtered, normalized, benchmarked VCF, chaining QC/trim, BWA-MEM2 alignment, duplicate marking, optional BQSR, calling (bcftools/GATK HaplotypeCaller/DeepVariant/DRAGEN), normalization, site+genotype filtering, annotation, and hap.py/vcfeval benchmarking. Use when deciding the pipeline-wide reference-genome commitment (GRCh38 analysis set vs T2T, ALT/decoy handling), sequencing the steps in the defensible order (normalize BEFORE annotate, filter site- then genotype-level), choosing the calling engine and single-sample vs cohort joint-calling, picking a filtering strategy by cohort size, or benchmarking stratified within GIAB confident regions. Hands off mechanism to the variant-calling and read-alignment component skills; not a re-teach of any single step.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end ATAC-seq workflow from FASTQ files to differential accessibility and TF footprinting. Covers alignment, peak calling with MACS3, QC metrics, and optional TOBIAS footprinting. Use when running end-to-end ATAC-seq analysis from FASTQ to differential accessibility.

日本語の概要は準備中です。原文の説明を表示しています。

Create or review Terraform infrastructure and plans. Use for cloud resources, IAM, networking, state management, and infrastructure changes.

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Installs CARLA's ScenarioRunner (the official scenario engine) and picks the branch that matches the CARLA in use — master for 0.9.14-0.9.16 (UE4), ue5-master for 0.10.0 (UE5), leaderboard-1.0/2.0/2.1 when driving the Leaderboard. Clones or checks out the branch, installs requirements, wires PYTHONPATH (including the `agents` package the carla wheel does not ship), and verifies the import. Use when the user asks to "install scenario runner", "set up SR", "run CARLA scenarios", "use OpenSCENARIO", or has a scenario_runner that fails to import.

日本語の概要は準備中です。原文の説明を表示しています。

Windows アプリ開発 (WinUI 3 / Windows App SDK 2.x) のライフサイクル・ウィンドウ・ 通知・リソース・ウィジェット・配置。AppInstance, 単一インスタンス化, RichActivation, PowerManager、 AppWindow, AppWindowPresenter, OverlappedPresenter, タイトルバー, DisplayArea, Win32 相互運用、 AppNotification, Toast, PushNotificationManager, バッジ通知、ResourceManager, MRT, PRI, ローカライズ、 WidgetProvider, WidgetManager, アダプティブカード、MSIX, 自己完結型, DeploymentManager, PackageVolume, IPackageValidator (パッケージ検証), RuntimeCompatibilityOptions, SemVer, サポート期間, リリースチャネル。

前回更新コミット (_/.last-update-docs で追跡) からの差分をもとに CLAUDE.md のスキル一覧・リポジトリ構造ツリーを更新する。 新スキル追加時、.claude/agents/ や .claude/rules/ の変更時、「ドキュメント更新して」「CLAUDE.md を更新して」などで使用。 コード内コメント・ドキュメンテーションコメントの補強を依頼された場合にも参照する指針を含む。

Windows アプリ開発 (Fluent Design / WinUI 3) のデザインガイドライン。 layout, alignment, spacing, geometry, elevation, breakpoints, Color, materials, Mica, Acrylic, Smoke, Reveal Focus, Reveal Highlight (非推奨), typography, Segoe Fluent Icons, app icons, motion, easing, page transitions, connected animation, parallax, reduce motion, haptics, NavigationView, TitleBar, TabView, CommandBar, menus, keyboard accelerators, access keys, accessibility, high contrast, globalization, RTL, widgets design。

Windows アプリ開発 (DirectX / WinRT メディア) のグラフィックス・メディア API リファレンス。 Direct2D (ID2D1Factory, ID2D1DeviceContext, ID2D1Bitmap1, ID2D1Effect, D2D1 Effects, ID2D1PathGeometry), DirectWrite (IDWriteFactory, IDWriteTextLayout, DWriteCore), Direct3D 11/12 (D3D11CreateDevice, D3D11On12, DXGI SwapChain, HLSL, D3D12 PipelineState, D3D12 DRED), Microsoft.UI.Composition (Compositor, Visual, ExpressionAnimation, InteractionTracker, MicaController), カメラ・画面キャプチャ (MediaCapture, MediaFrameReader, GraphicsCaptureSession, Windows Studio Effects, OpenCV)、音声・動画再生 (MediaPlayer, MediaPlaybackSession, AudioGraph, MediaTranscoder, AdaptiveMediaSource, HLS, DASH, CastingDevicePicker, AudioPlaybackConnection)。