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概要と使いどころ
HuggingFace Transformers with biomedical LMs (BioBERT, PubMedBERT, BioGPT, BioMedLM) for scientific NLP: NER (genes, diseases, chemicals), relation extraction, QA, text classification, abstract summarization. Covers loading, biomedical tokenization, inference pipelines, fine-tuning. Alternatives: spaCy en_core_sci_lg (rule-based NER), Stanza (biomedical models), NLTK.
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Out-of-core DataFrame for billion-row data via lazy evaluation and memory-mapped files. Use when data exceeds RAM (10 GB–TB) for fast aggregation, filtering, virtual columns, and visualization without loading. Supports HDF5, Arrow, Parquet, CSV with cloud (S3, GCS, Azure). Built-in ML transformers (scaling, PCA, K-means). In-memory: polars; distributed: dask.
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NEB-IRC activation energy pipeline for reaction barriers using GFN2-xTB and pysisyphus. Optimize reactant and product geometries, run CI-NEB path search, optimize the transition state with a Hessian, verify with IRC (one imaginary mode, endpoints matching reactant/product, single NEB maximum), and report the electronic and Gibbs barriers. Use when you need a transition state, reaction barrier, activation energy, minimum energy path, or intrinsic reaction coordinate. Covers reactant/product atom-ordering pitfalls, feasibility sizing for single-core runs, and thermochemistry corrections. Renders an IRC energy-profile plot and an animated TS imaginary-mode HTML viewer. For 2D reaction scheme drawing use rdkit-chemdraw-cdxml.
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GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to single-cell scale. Core SCENIC component.
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WSI processing for digital pathology. Tissue detection, tile extraction (random, grid, score-based), filter pipelines for H&E/IHC. For dataset prep, tile-based DL, slide QC. Use pathml for multiplexed imaging.
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Interactive viewer for microscopy. Displays 2D/3D/4D arrays as Image, Labels, Points, Shapes, Tracks layers; supports annotation, plugin analysis, headless screenshots. Core visualization for Python bioimage workflows. Use ImageJ/FIJI for macro processing; napari for Python-native interactive visualization and DL segmentation review.
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MS spectral matching and metabolite ID with matchms. Import spectra (mzML, MGF, MSP, JSON), filter/normalize peaks, score similarity (cosine, modified cosine, fingerprint), build reproducible pipelines, identify unknowns vs spectral libraries. Use pyopenms for full LC-MS/MS proteomics.
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15-agent hierarchical mesh coordination for v3 implementation. Orchestrates parallel execution across security, core, and integration domains following 10 ADRs with 14-week timeline.
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AI-assisted pair programming with multiple modes (driver/navigator/switch), real-time verification, quality monitoring, and comprehensive testing. Supports TDD, debugging, refactoring, and learning sessions. Features automatic role switching, continuous code review, security scanning, and performance optimization with truth-score verification.
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Best practices, design patterns, and common pitfalls for ROS1 (Robot Operating System 1) development. Use this skill when building ROS1 nodes, packages, launch files, or debugging ROS1 systems. Trigger whenever the user mentions ROS1, catkin, rospy, roscpp, roslaunch, roscore, rostopic, tf, actionlib, message types, services, or any ROS1-era robotics middleware. Also trigger for migrating ROS1 code to ROS2, maintaining legacy ROS1 systems, or building ROS1-ROS2 bridges. Covers catkin workspaces, nodelets, dynamic reconfigure, pluginlib, and the full ROS1 ecosystem.
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Provides comprehensive memory file management capabilities including auditing, quality assessment, and targeted improvements for files such as CLAUDE.md. Use when user asks to check, audit, update, improve, fix, maintain, or validate project memory files. Also triggers for "project memory optimization", "CLAUDE.md quality check", "documentation review", or when a project memory file needs to be created from scratch. This skill scans memory files, evaluates quality against standardized criteria, outputs detailed quality reports with scores and recommendations, then makes targeted updates with user approval.
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Provides AWS SDK for Java 2.x client configuration, credential resolution, HTTP client tuning, timeout, retry, and testing patterns. Use when creating or hardening AWS service clients, wiring Spring Boot beans, debugging auth or region issues, or choosing sync vs async SDK usage.
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Canonical rules for writing and reviewing Rust code in Shift's crates. Use whenever you add or change `.rs` code, especially error handling (`ok_or`, `ok_or_else`, `map_err`, `?`, `CoreError`, `StoreError`, `SlugError`, `BridgeError`), entity lookups by id, checked arithmetic and integer conversions, or helpers that several call sites repeat. Load `rustdoc` as well when the change adds or edits doc comments.
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When the user needs to identify at-risk accounts, understand why customers are leaving, reduce churn rate, build health scores, design save plays, or create win-back campaigns.
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When the user needs to design an interview process, create interview questions, build scorecards, calibrate interviewers, or evaluate candidates for a role.
日本語の概要は準備中です。原文の説明を表示しています。
Use when auditing a page for E-E-A-T signals. The agent reads the page and scores Experience, Expertise, Authoritativeness, and Trustworthiness — then tells you exactly what to add to each dimension.
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Databricks CLI operations and the parent/entry-point skill for Databricks CLI use: authentication, profile selection, and bundles. Load this first for CLI, auth, profile, and bundle tasks, then load the matching product skill. For finding or exploring data, answering questions about the data, or generating SQL, load the databricks-data-discovery skill (it routes to Genie One). Contains up-to-date guidelines for Databricks-related CLI tasks.
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Train ML models on Databricks. Use for: classification/regression/deep-learning (XGBoost, scikit-learn, LightGBM, PyTorch) with Optuna, @prod/@challenger aliases, batch scoring (spark_udf for plain models, fe.score_batch for feature-store-backed), custom PyFunc, custom ResponsesAgent (LangGraph + UC Function/Vector Search); UC feature tables + FeatureLookup + point-in-time joins + Lakebase online store; declarative Feature Views (create_feature, DeltaTableSource, RollingWindow/SlidingWindow/TumblingWindow, materialize_features, streaming Kafka features). NOT for: endpoint ops (databricks-model-serving), MLflow evaluation (databricks-mlflow-evaluation).
日本語の概要は準備中です。原文の説明を表示しています。
Compare and analyze contractor bids. Score proposals, identify scope gaps, and recommend selections.
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Implement proven sales methodologies (MEDDIC, BANT, Sandler, Challenger, SPIN) across your team. Generate framework-specific questions, score deals, train reps, and enforce consistent qualification. Use when implementing or optimizing sales processes.
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Multi-dimensional rep evaluation: activity, conversion, velocity, deal size. Peer benchmarking and coaching priority identification.
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Builds a custom lead scoring model for a business. Takes ICP definition, historical win/loss data, CRM export. Analyzes which attributes correlate with closed-won deals. Generates lead-scoring-model.md with scoring dimensions, point values, thresholds, CRM implementation guide, and validation methodology. Can also score a batch of current leads against the model.
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Write job posts that make the right person apply -- real role clarity, honest selling points, salary range handling, and requirements pruned to what actually predicts success. Small businesses lose great candidates to bad posts long before the interview. Feeds cowork-hiring-screener and hiring-scorecard downstream.
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Uses MCP Connectors to read Gmail inbound leads, score them by ICP fit, draft personalized responses, and log qualified leads to your CRM. Turns your inbox into an automated pipeline.
日本語の概要は準備中です。原文の説明を表示しています。