2,868 件 ・ 関連度順
概要と使いどころ
Queries gnomAD v4 (807k samples), v3, v2.1.1, and constraint metrics with grpmax FAF95, bottleneck-group exclusion, LOEUF interpretation, SV/CNV/mtDNA catalogs, and Whiffin max-credible-AF framework. Use when filtering rare variants, applying ACMG BS1/BA1, ranking genes by LoF intolerance, or selecting between v2 (GRCh37 + chrX/Y constraint) and v4 (GRCh38 + 807k samples).
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Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocalization triangulation, phenome-wide on-target adverse-effect scans, cross-platform Olink/SomaScan replication, and PAV (protein-altering variant) sensitivity. Use when nominating or de-risking a drug target from plasma-proteome GWAS, mimicking pharmacological inhibition via cis-pQTL instruments, separating shared-causal from LD-confounded signal under the Schmidt 2020 cis-MR framework, screening on-target adverse phenotypes pheWAS-style, or producing publication-grade STROBE-MR plus PP.H4 evidence for a target gene.
日本語の概要は準備中です。原文の説明を表示しています。
Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Validate alignment quality with insert size distribution, proper pairing rates, GC bias, strand balance, and other post-alignment metrics. Use when verifying alignment data quality before variant calling or quantification.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze TF motif accessibility variability across samples or single cells using chromVAR. Use when identifying TF motifs whose accessibility correlates with conditions, computing per-sample motif z-scores after matched background correction, comparing to ArchR / Signac equivalents, or distinguishing motif-accessibility signal from per-site footprinting.
日本語の概要は準備中です。原文の説明を表示しています。
Build a throwaway prototype to flush out a design before committing to it. Routes between two branches — a runnable terminal app for state/business-logic questions, or several radically different UI variations toggleable from one route. Use when the user wants to prototype, sanity-check a data model or state machine, mock up a UI, explore design options, or says "prototype this", "let me play with it", "try a few designs".
日本語の概要は準備中です。原文の説明を表示しています。
Throwaway HTML mockups: 2-3 design variants to compare.
日本語の概要は準備中です。原文の説明を表示しています。
Subjects every non-trivial decision to a fresh-context adversarial review before it stands. Use when correctness matters more than speed, when working in unfamiliar code, when stakes are high (production, security-sensitive logic, irreversible operations), or any time a confident output would be cheaper to verify now than to debug later.
日本語の概要は準備中です。原文の説明を表示しています。
Orchestrate autonomous AI development pipelines through your Kanban board (Asana, GitHub Projects, Linear). Manages multi-worker Claude Code dispatch, deterministic quality gates, adversarial review, per-task cost tracking, and crash-proof pipeline execution.
日本語の概要は準備中です。原文の説明を表示しています。
Multi-agent collaboration plugin that spawns N parallel subagents competing on the same task via git worktree isolation. Agents work independently, results are evaluated by metric or LLM judge, and the best branch is merged. Use when: user wants multiple approaches tried in parallel — code optimization, content variation, research exploration, or any task that benefits from parallel competition. Requires: a git repo.
日本語の概要は準備中です。原文の説明を表示しています。
Use when assessing AI/ML systems for prompt injection, jailbreak vulnerabilities, model inversion risk, data poisoning exposure, or agent tool abuse. Covers MITRE ATLAS technique mapping, injection signature detection, and adversarial robustness scoring.
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When the user needs to generate, iterate, or scale ad creative for paid advertising. Use when they say 'write ad copy,' 'generate headlines,' 'create ad variations,' 'bulk creative,' 'iterate on ads,' 'ad copy validation,' 'RSA headlines,' 'Meta ad copy,' 'LinkedIn ad,' or 'creative testing.' This is pure creative production — distinct from paid-ads (campaign strategy). Use ad-creative when you need the copy, not the campaign plan.
日本語の概要は準備中です。原文の説明を表示しています。
Advogado especialista em todas as areas do Direito brasileiro: familia, criminal, trabalhista, tributario, consumidor, imobiliario, empresarial, civil e constitucional.
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Advogado criminalista especializado em Maria da Penha, violencia domestica, feminicidio, direito penal brasileiro, medidas protetivas, inquerito policial e acao penal.
日本語の概要は準備中です。原文の説明を表示しています。
Run a skeptical Claude review over the current diff or branch range.
日本語の概要は準備中です。原文の説明を表示しています。
Turn briefs, mockups, and product context into Stitch UI screens, design systems, variants, prototypes, Tailwind-friendly HTML, and screenshots. Use when the user wants to explore a screen, edit an existing Stitch project, compare visual directions, build a multi-screen prototype, or save local design/code-export artifacts from natural-language input.
日本語の概要は準備中です。原文の説明を表示しています。
Rename a code symbol (variable, function, class) across a specified scope.
日本語の概要は準備中です。原文の説明を表示しています。
Expert-level stellar physics covering stellar structure and evolution, nucleosynthesis, stellar atmospheres, variable stars, binary systems, and stellar populations.
日本語の概要は準備中です。原文の説明を表示しています。
Expert-level calculus knowledge. Use when working with limits, derivatives, integrals, multivariable calculus, vector calculus, differential equations, series, or optimization. Also use when the user mentions 'derivative', 'integral', 'limit', 'chain rule', 'gradient', 'divergence', 'curl', 'Taylor series', 'Fourier series', 'partial derivative', 'double integral', 'line integral', 'Stokes theorem', or 'Lagrange multipliers'.
日本語の概要は準備中です。原文の説明を表示しています。
Expert-level differential equations knowledge. Use when working with ordinary differential equations, partial differential equations, systems of ODEs, Laplace transforms, Fourier methods, boundary value problems, stability analysis, or numerical methods for ODEs. Also use when the user mentions 'ODE', 'PDE', 'initial value problem', 'boundary value problem', 'Laplace transform', 'separation of variables', 'eigenvalue problem', 'heat equation', 'wave equation', 'Laplace equation', 'stability', or 'phase plane'.
日本語の概要は準備中です。原文の説明を表示しています。
Expert-level topology knowledge. Use when working with topological spaces, continuity, compactness, connectedness, metric spaces, homeomorphisms, fundamental groups, homology, manifolds, or algebraic topology. Also use when the user mentions 'open set', 'closed set', 'compactness', 'connectedness', 'homeomorphism', 'homotopy', 'fundamental group', 'covering space', 'manifold', 'homology', 'Euler characteristic', or 'topological invariant'.
日本語の概要は準備中です。原文の説明を表示しています。
Perform a Cynical Review and produce a findings report. Use when the user requests a critical review of something
日本語の概要は準備中です。原文の説明を表示しています。
Walk every branching path and boundary condition in content, report only unhandled edge cases. Orthogonal to adversarial review - method-driven not attitude-driven. Use when you need exhaustive edge-case analysis of code, specs, or diffs.
日本語の概要は準備中です。原文の説明を表示しています。
Review code changes adversarially using parallel review layers (Blind Hunter, Edge Case Hunter, Acceptance Auditor) with structured triage into actionable categories. Use when the user says "run code review" or "review this code"
日本語の概要は準備中です。原文の説明を表示しています。