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Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.

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Create hierarchical project plans optimized for solo agentic development. Use when planning projects, phases, or tasks that Claude will execute. Produces Claude-executable plans with verification criteria, not enterprise documentation. Handles briefs, roadmaps, phase plans, and context handoffs.

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Execute Codex CLI for code analysis, refactoring, and automated code changes. Use when you need to delegate complex code tasks to Codex AI with file references (@syntax) and structured output.

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Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.

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Interactive Archon integration for knowledge base and project management via REST API. On first use, asks for Archon host URL. Use when searching documentation, managing projects/tasks, or querying indexed knowledge. Provides RAG-powered semantic search, website crawling, document upload, hierarchical project/task management, and document versioning. Always try Archon first for external documentation and knowledge retrieval before using other sources.

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Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.

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Track complex, multi-session work with dependency graphs using bd (beads) issue tracker. Use when work spans multiple sessions, has complex dependencies, or requires persistent context across compaction cycles. For simple single-session linear tasks, TodoWrite remains appropriate.

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Stop and consult this skill whenever your response would include specific facts about Anthropic's products. Covers: Claude Code (how to install, Node.js requirements, platform/OS support, MCP server integration, configuration), Claude API (function calling/tool use, batch processing, SDK usage, rate limits, pricing, models, streaming), and Claude.ai (Pro vs Team vs Enterprise plans, feature limits). Trigger this even for coding tasks that use the Anthropic SDK, content creation mentioning Claude capabilities or pricing, or LLM provider comparisons. Any time you would otherwise rely on memory for Anthropic product details, verify here instead — your training data may be outdated or wrong.

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Propose a new change with all artifacts generated in one step. Use when the user wants to quickly describe what they want to build and get a complete proposal with design, specs, and tasks ready for implementation.

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Evaluates code against Apple's App Store Review Guidelines. Use this skill when reviewing iOS, macOS, tvOS, watchOS, or visionOS app code (Swift, Objective-C, React Native, or Expo) to identify potential App Store rejection issues before submission. Triggers on tasks involving app review preparation, compliance checking, or App Store submission readiness.

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Postgres best practices maintained by Supabase, for Postgres running anywhere. Load this skill BEFORE writing or changing anything that lives in a Postgres database: creating or altering tables and columns (including choosing column types), schema design, migrations and declarative schema files, RLS policies and the tests that verify them, indexes, triggers, database functions, queues and scheduled jobs (pg_cron, pgmq), vector/semantic search (pgvector), and restoring dumps (pg_restore) or importing data. Also load it when diagnosing slow queries, high CPU, timeouts, EXPLAIN plans, connection exhaustion, locking, bloat, or rows visible to the wrong user or tenant. This is not just a performance guide — schema, migration, security, and SQL authoring tasks need these rules too, even for a one-column change or a single query.

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React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.

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Turborepo monorepo build system guidance. Triggers on: turbo.json, task pipelines, dependsOn, caching, remote cache, the "turbo" CLI, --filter, --affected, CI optimization, environment variables, internal packages, monorepo structure/best practices, and boundaries. Use when user: configures tasks/workflows/pipelines, creates packages, sets up monorepo, shares code between apps, runs changed/affected packages, debugs cache, or has apps/packages directories.

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React and Next.js performance optimization guidelines from Vercel Engineering. This skill should be used when writing, reviewing, or refactoring React/Next.js code to ensure optimal performance patterns. Triggers on tasks involving React components, Next.js pages, data fetching, bundle optimization, or performance improvements.

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React Native and Expo best practices for building performant mobile apps. Use when building React Native components, optimizing list performance, implementing animations, or working with native modules. Triggers on tasks involving React Native, Expo, mobile performance, or native platform APIs.

日本語の概要は準備中です。原文の説明を表示しています。

Propose a new change with all artifacts generated in one step. Use when the user wants to quickly describe what they want to build and get a complete proposal with design, specs, and tasks ready for implementation.

日本語の概要は準備中です。原文の説明を表示しています。

Use when working with the Resend email API — sending transactional emails (single or batch), receiving inbound emails via webhooks, managing email templates, tracking delivery events, managing domains, contacts, broadcasts, webhooks, API keys, automations, events, viewing API request logs, or setting up the Resend SDK. Always use this skill when the user mentions Resend, even for simple tasks like "send an email with Resend" — the skill contains critical gotchas (idempotency keys, webhook verification, template variable syntax) that prevent common production issues.

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Use when adding durable execution to a TypeScript project — building retry-safe webhook handlers, background jobs that survive crashes, scheduled tasks, or long-running workflows that outlive a single request. Covers Inngest SDK installation, client config, environment variables, serve endpoints (Next.js, Express, Hono, Fastify), connect-as-worker mode, and the local dev server.

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Use when the user wants to design, redesign, shape, critique, audit, polish, clarify, distill, harden, optimize, adapt, animate, colorize, extract, or otherwise improve a frontend interface. Covers websites, landing pages, dashboards, product UI, app shells, components, forms, settings, onboarding, and empty states. Handles UX review, visual hierarchy, information architecture, cognitive load, accessibility, performance, responsive behavior, theming, anti-patterns, typography, fonts, spacing, layout, alignment, color, motion, micro-interactions, UX copy, error states, edge cases, i18n, and reusable design systems or tokens. Also use for bland designs that need to become bolder or more delightful, loud designs that should become quieter, live browser iteration on UI elements, or ambitious visual effects that should feel technically extraordinary. Not for backend-only or non-UI tasks.

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Build modern, composable, and accessible React UI components following the components.build specification. Use when creating, reviewing, or refactoring component libraries, design systems, or any reusable UI components. Triggers on tasks involving component APIs, composition patterns, accessibility, styling systems, or TypeScript props.

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Maintain the canonical TASKS.csv with permanent IDs, provenance and lifecycle history; list, add, update, complete, cancel or import selected actions.

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Dataflow workflow engine for scalable bioinformatics pipelines. Defines processes (containerized tasks) connected by channels; runs local, HPC (SLURM/SGE), cloud (AWS/GCP/Azure), or Kubernetes via a single config change. Powers nf-core. Use Snakemake for rule-based Python workflows; use Nextflow for containerized, cloud-native, and nf-core pipelines.

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Provides patterns to deploy ECS tasks and services with GitHub Actions CI/CD. Use when building Docker images, pushing to ECR, updating ECS task definitions, deploying ECS services, integrating with CloudFormation stacks, configuring AWS OIDC authentication for GitHub Actions, and implementing production-ready container deployment pipelines. Supports ECS deployments with proper security (OIDC or IAM keys), multi-environment support, blue/green deployments, ECR private repositories with image scanning, and CloudFormation infrastructure updates.

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Provides comprehensive Turborepo monorepo management guidance for TypeScript/JavaScript projects. Use when creating Turborepo workspaces, configuring turbo.json tasks, setting up Next.js/NestJS apps, managing test pipelines (Vitest/Jest), configuring CI/CD, implementing remote caching, or optimizing build performance in monorepos

日本語の概要は準備中です。原文の説明を表示しています。