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概要と使いどころ
Prepare a proportionate work plan with outcomes, steps, dependencies and acceptance evidence. Use to plan substantial work or coordinate an approved team; a plan-only request does not authorize implementation.
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Initialize or inspect a project, maintain sourced current facts and record durable decisions. Use for project context or remember-this requests; other record types retain their owners.
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Look up HPD violations, complaints, and building registration for NYC residential buildings. Use when the user asks about housing-code violations, tenant complaints, or HPD registration at an address. NYC only; for DOB and ECB violations use /as:nyc-dob-violations.
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Monarch Initiative knowledge graph REST API for disease-gene-phenotype associations and cross-species orthology. MONDO disease-to-gene/phenotype, HP phenotype profiles, cross-species comparisons. Use for rare disease gene prioritization and phenotype-based candidate ranking. For GWAS use gwas-database; for clinical pathogenicity use clinvar-database.
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Bulk RNA-seq DE with PyDESeq2: load counts, normalize, fit negative binomial models, Wald test (BH-FDR), LFC shrinkage, volcano/MA plots. Use for two-group comparisons, multi-factor designs with batch correction, multiple contrasts.
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Cloud quantum chemistry platform with Python SDK. Run geometry optimization, conformer generation, torsional scans, and energy minimization (DFT/semiempirical), and retrieve properties (dipole, partial charges, frontier orbitals) — no local QC software or HPC needed.
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Constraint-based (COBRA) analysis of genome-scale metabolic models: FBA, FVA, knockouts, flux sampling, production envelopes, gapfilling, media optimization. Use for strain design, essential gene ID, flux analysis. For kinetic modeling use tellurium; for visualization use Escher.
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Python framework for single- and multi-objective optimization with evolutionary algorithms. Define vectorized objectives and constraints; solve with NSGA-II, NSGA-III, MOEA/D, GAs, or differential evolution. Analyze Pareto fronts, visualize trade-offs, customize operators and callbacks. For engineering design, hyperparameter search, and conflicting objectives. Alternatives: scipy.optimize (single-objective, gradient), platypus, jMetalPy (Java).
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Structured peer review of manuscripts and grants. 7-stage evaluation: initial assessment, section review, statistical rigor, reproducibility, figure integrity, ethics, writing. Covers CONSORT/STROBE/PRISMA and report structure. For evidence quality see scientific-critical-thinking; scoring see scholar-evaluation.
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Methodology for exploratory data analysis on scientific files. Decision frameworks by data type (tabular, sequence, image, spectral, structural, omics), quality assessment, report generation, format detection across 200+ formats. Use when given a data file for initial exploration or to pick an analysis before a pipeline.
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Core Python library for astronomy/astrophysics: units with dimensional analysis, celestial coordinate transforms (ICRS/Galactic/AltAz/FK5), FITS I/O, tables (FITS/HDF5/VOTable/CSV), cosmology (Planck18, distance/age), precise time (UTC/TAI/TT/TDB, Julian, barycentric), WCS pixel-world mapping, model fitting. For general tables use pandas/polars; for radio interferometry use CASA.
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Poisson-model peak caller for ChIP-seq/ATAC-seq BAMs. MACS3 callpeak finds enriched regions (TF sites or histone marks) vs input/IgG; outputs BED narrowPeak/broadPeak for motif analysis, annotation, and differential binding. Use narrow peaks for TF ChIP-seq and ATAC-seq; broad for H3K27me3, H3K9me3, and other broad marks.
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Evaluates code against Apple's App Store Review Guidelines. Use this skill when reviewing iOS, macOS, tvOS, watchOS, or visionOS app code (Swift, Objective-C, React Native, or Expo) to identify potential App Store rejection issues before submission. Triggers on tasks involving app review preparation, compliance checking, or App Store submission readiness.
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Stream-JSON chaining for multi-agent pipelines, data transformation, and sequential workflows
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Security hardening and best practices for robotic systems, covering SROS2 DDS security, network segmentation, secrets management, secure boot, and the physical-cyber safety intersection. Use this skill when securing ROS2 communications, configuring DDS encryption and access control, hardening robot onboard computers, managing certificates and credentials, setting up network segmentation for robot fleets, or addressing the unique security challenges where cyber vulnerabilities become physical safety risks. Trigger whenever the user mentions SROS2, DDS security, robot security, robot hardening, ROS2 encryption, ROS2 access control, robot network security, secure robot deployment, robot certificates, keystore generation, robot firewall, e-stop security, safety controller isolation, or IEC 62443 for robotics.
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AWS serverless and event-driven architecture expert based on Well-Architected Framework. Use when building serverless APIs, Lambda functions, REST APIs, microservices, or async workflows. Covers Lambda with TypeScript/Python, API Gateway (REST/HTTP), DynamoDB, Step Functions, EventBridge, SQS, SNS, and serverless patterns. Essential when user mentions serverless, Lambda, API Gateway, event-driven, async processing, queues, pub/sub, or wants to build scalable serverless applications with AWS best practices.
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Configure AWS MCP servers for documentation search and API access. Use when setting up AWS MCP, configuring AWS documentation tools, troubleshooting MCP connectivity, or when user mentions aws-mcp, awsdocs, uvx setup, or MCP server configuration. Covers both Full AWS MCP Server (with uvx + credentials) and lightweight Documentation MCP (no auth required).
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SST v4 (Ion) expert for managing AWS resources as code with the Pulumi-backed framework. Use when writing or editing sst.config.ts, building infra/ modules (sst.aws.Function/Bucket/Dynamo/Cron/Service/Router, sst.Secret, sst.Linkable, raw aws.* Pulumi resources), wiring resource links, scoping IAM, or running sst deploy/dev/diff/remove. Essential when the user mentions SST, sst.config.ts, $config, $transform, $interpolate, sst.aws.*, sst.Secret, Pulumi/Ion, "sst deploy", a failed SST deploy (ConflictException on a resource-type change, "Identifier '__filename' has already been declared", MalformedPolicyDocument on an Output<T>), or wants to scaffold/troubleshoot AWS infrastructure with SST. Also use when a request to "deploy my AWS stack" or "add a Lambda/bucket/table" is made in a repo that already contains an sst.config.ts (using $config) or an sst dependency. Do NOT use when the task is primarily AWS CDK, Terraform, raw CloudFormation, or SAM with no SST present — those have their own tooling.
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AWS cost optimization, monitoring, and operational excellence expert. Use when analyzing AWS bills, estimating costs, setting up CloudWatch alarms, querying logs, auditing CloudTrail activity, or assessing security posture. Essential when user mentions AWS costs, spending, billing, budget, pricing, CloudWatch, observability, monitoring, alerting, CloudTrail, audit, or wants to optimize AWS infrastructure costs and operational efficiency.
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Skill for creating and managing a Design System using Tailwind CSS and shadcn/ui. Use when defining design tokens, setting up theming with CSS variables, building a consistent UI component library, initializing a design system configuration, or wrapping shadcn/ui components into design system primitives.
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Provides AWS Secrets Manager patterns for AWS SDK for Java 2.x, including secret retrieval, caching, rotation-aware access, and Spring Boot integration. Use when storing or reading secrets in Java services, replacing hardcoded credentials, or wiring secret-backed configuration into applications.
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Provides AWS SDK for Java 2.x client configuration, credential resolution, HTTP client tuning, timeout, retry, and testing patterns. Use when creating or hardening AWS service clients, wiring Spring Boot beans, debugging auth or region issues, or choosing sync vs async SDK usage.
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Provides fault tolerance patterns for Spring Boot 3.x using Resilience4j. Use when implementing circuit breakers, handling service failures, adding retry logic with exponential backoff, configuring rate limiters, or protecting services from cascading failures. Generates circuit breaker, retry, rate limiter, bulkhead, time limiter, and fallback implementations. Validates resilience configurations through Actuator endpoints.
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Provides patterns to configure AWS RDS (Aurora, MySQL, PostgreSQL) with Spring Boot applications. Configures HikariCP connection pools, implements read/write splitting, sets up IAM database authentication, enables SSL connections, and integrates with AWS Secrets Manager. Use when setting up RDS connections in Spring Boot, configuring connection pooling, or managing database credentials securely.
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