「enhance」の検索結果

Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify chromatin states with ChromHMM, identify super-enhancers with ROSE, understand the functional validation hierarchy (CRISPR > MPRA > reporter), or characterize non-coding genomic regions. Covers the full workflow from ENCODE cCRE lookup through chromatin state segmentation to functional validation and enhancer-gene linkage. Use this skill for ANY regulatory element discovery, classification, or characterization task.

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Full enhancement pipeline for an existing Lattice skill — rewrites a molecule or atom to modern-capable-model grade: restores degraded grammar, deduplicates, hardens gates and branching to one-unambiguous-action precision, verifies zero behavioral loss against a pre-capture diff, then runs the combined QA gate (skill-review, skill-tighten, skill-validate) and an independent fresh-context verifier, fixing everything found. Consumer-first: optimized for first-time open-source users on fresh repos with minimal .lattice/ setup, running capable models. Use when the user says 'enhance this skill', 'upgrade this molecule', 'modernize this skill', 'optimize this skill', 'make this skill production grade', 'full enhancement', 'polish this molecule like design-blueprint', or names a molecule/atom to overhaul. For gap-finding only use skill-review; for conventions only use skill-validate — this skill runs the whole loop end to end.

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Identifies super-enhancers from H3K27ac ChIP-seq data using ROSE and related tools. Use when studying cell identity genes, cancer-associated regulatory elements, or master transcription factor binding regions that cluster into large enhancer domains.

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Set up player input in Unreal Engine 5 with Enhanced Input: Input Actions, Input Mapping Contexts, modifiers and triggers, adding the mapping context, and binding actions by ETriggerEvent. Use when wiring movement/look/jump input, creating IA_/IMC_ assets, binding in C++ or Blueprints, or when the user mentions Enhanced Input, Input Mapping Context, Input Action, IA_/IMC_, or ETriggerEvent.

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Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

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Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

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Read BEFORE troubleshooting or enhancing camera image quality. Diagnoses and enhances image quality from cameras connected via Image Acquisition Toolbox or USB Webcams support package. Discovers camera capabilities at runtime, analyzes captured images for quality issues (brightness, contrast, sharpness, noise, color balance, backlighting), suggests hardware setting adjustments tailored to the specific camera, and applies Image Processing Toolbox enhancement functions. Use when a user wants to improve camera image quality, troubleshoot dark/blurry/noisy/grainy/ overexposed/washed out/color cast images, or optimize camera settings.

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Enhancement overlay for multi-agent / tool-using coder agents. Encodes the per-agent tool- scoping discipline that role-based frameworks (CrewAI, LangChain) document only as a passing best-practice: which agent gets which tool, and why blanket-sharing every tool to every agent is a correctness and blast-radius risk. Activates when an agent system has tools AND there is more than one agent (or one agent holding many tools). Treat a tool as a capability grant; scope by least-privilege. ENHANCE overlay — read alongside [[crewai]], [[agentsop-http-tool-wrapping]], [[agentsop-llm-tool-idempotency]]. Search keywords: which tools per agent, least-privilege agent, agent tool access, tool permissions, limit agent tools, scope tools to roles.overlay_type: enhancement

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Use when enhancing, upscaling, restoring, denoising, sharpening, deinterlacing, stabilizing, motion-deblurring, colorizing, SDR-to-HDR converting, or frame-rate/slow-motion converting video (and secondarily images) with Topaz Labs — whether cleaning up AI-generated video, compressed UGC, or old archival footage, or building a generate-low-res-then-upscale delivery pipeline. Covers choosing the right named Topaz model for a specific footage problem, setting parameters, driving the Topaz Platform (Video/Image) REST API's async job lifecycle, judging when enhancement helps versus when it introduces artifacts (over-smoothing, temporal shimmer, face hallucination), and QA of enhanced output. Do not use for originating new video content, non-Topaz upscalers, or purely editorial cuts.

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Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

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The enhancement layer for AI-generated content. This skill covers AI-powered visual effects, compositing, upscaling, restoration, and post-production magic—turning raw AI output into polished, professional content. AI generation gets you 80% of the way. Visual effects get you the remaining 20% that separates "clearly AI" from "how did they do that?" This skill covers ComfyUI workflows, Runway's AI tools, intelligent upscaling, rotoscoping, color grading, and the integration of AI elements into traditional footage. The practitioners of this skill are technical artists who understand both traditional VFX workflows and the new AI-native approaches that are revolutionizing post-production. Use when "AI visual effects, VFX, upscale, upscaling, composite, rotoscope, background removal, color grade, inpaint, outpaint, style transfer, enhance, ComfyUI, post-production AI, vfx, visual-effects, compositing, upscaling, post-production, comfyui, enhancement, color-grading" mentioned.

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Semantic codebase search, code indexing, and prompt enhancement via standalone CLI. Use when: (1) Semantic code search with natural language queries, (2) Code indexing for remote codebase retrieval, (3) Prompt enhancement with codebase context, (4) Before grep/find/glob operations for better accuracy, (5) Complex requirements clarification, (6) Large codebase navigation. Triggers: "search context", "enhance prompt", "find code that", "index project", "clarify requirements". IMPORTANT: Always use ace-tool BEFORE grep/find/glob for semantic-level code location.

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Calculates required credit enhancement levels with loss modeling, attachment/detachment points, and rating agency methodology. Use when sizing credit enhancement, modeling loss scenarios, or determining tranche subordination.

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Integrate multiple ENCODE data types (RNA-seq, ATAC-seq, Histone ChIP-seq, TF ChIP-seq) for a tissue/cell type to build a comprehensive regulatory landscape. Use when the user wants to answer "what are the enhancers, promoters, and regulatory elements active in my tissue, and which transcription factors control them?" by layering expression, chromatin accessibility, histone marks, and TF binding data. Follows the Mawla et al. 2023 framework for cross-assay integration of islet cell type-specific data. Handles chromatin state annotation (ChromHMM), enhancer-gene linkage, TF motif enrichment, and cell type-specific regulatory element identification. Use for ANY multi-omic analysis, enhancer discovery, regulatory network construction, or epigenomic characterization using ENCODE data.

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Enhance and improve existing AI prompts using professional techniques from a 2,500+ prompt database. Adds detail, fixes structure, optimizes for specific models, and applies proven patterns from top-performing prompts. Use when user says "enhance my prompt", "improve this prompt", "make this prompt better", "optimize prompt", "fix my prompt", or "upgrade this prompt".

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Configure the Industries Enhanced Timeline in Health Cloud to display clinical events, custom object records, and activity history on a patient or member record. Trigger keywords: Enhanced Timeline, TimelineObjectDefinition, Industries Timeline, timeline categories, clinical event display, timeline configuration. NOT for building a custom timeline or patient-card LWC — use apex/health-cloud-lwc-components. NOT for the standard Task and Event activity timeline — use admin/activity-and-task-patterns.

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Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

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Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

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[Skill Management] Use when enhancing, compressing, or expanding prompts, docs, or skills with attention anchoring [INTELLIGENT ROUTING]. Flag: --op={compress|expand|enhance} (default enhance); --op=compress strips token bloat, --op=expand reconstructs compressed text.

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Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

日本語の概要は準備中です。原文の説明を表示しています。

Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

日本語の概要は準備中です。原文の説明を表示しています。

Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

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CLI modernization and hooks system enhancement for claude-flow v3. Implements interactive prompts, command decomposition, enhanced hooks integration, and intelligent workflow automation.

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