Expert-level chemical process design covering process flow diagrams, mass and energy balances, equipment sizing, economic evaluation, and sustainable process design.
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概要と使いどころ
Expert-level chemical process design covering process flow diagrams, mass and energy balances, equipment sizing, economic evaluation, and sustainable process design.
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Tests APIs for mass assignment (auto-binding) vulnerabilities where clients can modify object properties they should not have Erişim: by including additional parameters in API requests. The tester identifies writable endpoints, adds undocumented fields to request bodies (role, isAdmin, price, balance), and checks if the server binds these to the data model without filtering. Part of OWASP API3:2023 Broken Object Property Level Authorization. Activates for requests involving mass assignment ...
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Hunt fintech-specific GraphQL vulnerabilities: money-movement mutations (transfers, redemptions, withdrawals, card top-ups), ledger/balance/portfolio query IDOR, decimal-precision and rounding abuse, idempotency-key bypass enabling double-spend, KYC/PII field-level authorization gaps, and admin-override mutations reachable via mass assignment. Distinct from hunt-graphql, which owns generic GraphQL discovery and IDOR/mutation methodology — this skill owns the delta introduced when a GraphQL layer sits in front of a ledger, wallet, payments, banking, brokerage, or lending backend, where a resolver bug moves real money instead of just leaking data. Use when hunting a fintech, banking, payments, wallet, neobank, brokerage, or lending target that exposes a GraphQL API, or when a schema/response includes balance, transfer, ledger, redeem, quote, KYC, or account-linking fields.
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Think and work like an expert Agricultural Engineer. Use when a task calls for Agricultural Engineer judgment. Reasons from mass, energy, and momentum balances on variable biological media through ET-based scheduling, psychrometric grain-drying balances, ASABE D497 draft estimates, EPANET pipe networks, and RTK-GNSS/ISOBUS precision-ag validation while treating soil compaction, clogged drip emitters, grain-bin hotspots, GPS drift, and uncalibrated yield monitors as first-class failure modes.
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Estimates intracellular metabolic fluxes from steady-state carbon-13 isotope-tracing measurements using validated atom maps, mfapy isotope simulation, constrained multistart fitting, and flux-profile diagnostics. Use for 13C-MFA, carbon tracing, mass isotopomer distributions (MDVs/MIDs), positional isotopomers, parallel tracer experiments, and determining whether labeling data constrain a pathway flux. Distinguishes measured-label inference from COBRA flux balance analysis and flags experiments requiring nonstationary MFA.
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Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.
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This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry. Use this skill whenever you are evaluating AI for scientific discovery, tackling "root node" problems, designing reinforcement learning systems, or discussing AGI timelines, safety, and global governance. Reach for it when the user faces massive combinatorial search spaces, wants to apply AI to physical/biological sciences (like digital biology), or needs to balance rapid AI scaling with the rigorous scientific method. Apply these mental models to shift the focus from building consumer apps to using AI as the ultimate meta-solution for understanding reality.
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Think and work like an expert Industrial Ecologist. Use when a task calls for Industrial Ecologist judgment. Reasons from mass balance closure, in-use stocks, and system boundaries through STAN (ÖNorm S 2096), dynamic MFA with Weibull lifetime distributions, EEIO tables (EXIOBASE, USEEIO) and pedigree-scored Monte Carlo while treating non-closing residuals, re-export trade hubs, downcounted informal-sector leakage, and Kalundborg-copied symbiosis without quality-spec match as first-class failure modes.
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Think and work like an expert Geochemist. Use when a task calls for Geochemist judgment. Reasons from Gibbs equilibria, mass and isotope balance, and fluid–rock interaction through stable (δ) and radiogenic (ε, isochron) systems, ICP-MS/LA-ICP-MS/TIMS/MC-ICP-MS/IRMS, PHREEQC/Perple_X phase modeling, and EarthChem/GeoReM workflows while treating alteration, matrix effects, Pb loss, mixing arrays, and Fretwell’s Law violations as first-class failure modes.
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Think and work like an expert Industrial Microbiologist. Use when a task calls for Industrial Microbiologist judgment. Reasons from SmF/SSF physiology, fed-batch μ/OTR–OUR/RQ, DoE media optimization, PAT (Raman soft sensors), ICH Q8/Q7 characterization, bioleaching, SVI/F/M filament ID, and phage (10⁴–10⁶ PFU/mL) plant hygiene; treats antifoam kLa penalty, F₀ CIP/SIP cold spots, DSP mass balance, and golden-batch vs biofilm red herrings as first-class failure modes.
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Think and work like an expert Environmental Chemist. Use when a task calls for Environmental Chemist judgment. Reasons from thermodynamic partitioning (K_oc/K_ow, Henry's law), pathway-specific half-lives, and mass balance through GC-MS/LC-MS/MS/ICP-MS analysis, EPI Suite and fugacity fate models, and EPA SW-846 QA/QC while treating blank contamination, matrix suppression, censored sub-LOD data, and unscoped transformation products as first-class failure modes.
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Think and work like an expert Environmental Engineer. Use when a task calls for Environmental Engineer judgment. Reasons from mass balances, reaction kinetics, source-pathway-receptor transport, and permit limits through BioWin/GPS-X, SWMM, AERMOD/CALPUFF, GAC/IX and activated-sludge design, and 40 CFR Part 136 QA/QC, while treating nitrifier washout, clarifier upset, PFAS breakthrough, and remediation rebound as first-class failure modes.
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Think and work like an expert Ecosystem Ecologist. Use when a task calls for Ecosystem Ecologist judgment. Reasons from NEE/NEP mass balance, ecological stoichiometry, and u*-filtered eddy covariance; processes with ONEFlux/REddyProc, NEON DP4.00200, and CENTURY/DayCent while treating gap-fill partitioning artifacts, chamber pressure pulses, harvest omission, and footprint shifts as first-class failure modes.
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Think and work like an expert Carbon Cycle Scientist. Use when a task calls for Carbon Cycle Scientist judgment. Reasons from carbon mass balance across reservoirs and timescales, sign conventions, and budget closure through the Global Carbon Budget protocol, ONEFlux/REddyProc eddy-covariance processing, atmospheric inversions (CarbonTracker, CAMS, GEOS-Chem), Δ¹⁴C/δ¹³C isotopic partitioning, and ILAMB model evaluation while treating NEE sign mismatches, gap-filled GPP read as measured, fixed-depth SOC comparisons, and uncounted lateral aquatic carbon export as first-class failure modes.
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Think and work like an expert Chemical Engineer. Use when a task calls for Chemical Engineer judgment. Reasons from closing mass, energy, and momentum balances and competing equilibrium/kinetics/transport regimes through Aspen Plus/HYSYS flowsheeting, McCabe-Thiele and Damkohler-based sizing, pinch analysis, and HAZOP/LOPA with API 520/521 relief, while treating azeotrope-pinched columns, reactor runaway, recycle impurity accumulation, and pump cavitation (NPSHa<NPSHr) as first-class failure modes.
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Think and work like an expert Biosystems & Agricultural Process Engineer. Use when a task calls for Biosystems & Agricultural Process Engineer judgment. Reasons from coupled heat and mass transfer, moisture sorption (EMC/ERH on D245.7 isotherms), respiration, and closed unit-operation balances through ASABE standards (S352.2 oven moisture, S448 Page thin-layer kinetics, D272.3 airflow resistance), psychrometric aeration analysis, and SuperPro/Aspen bioprocess simulation while treating wet- vs dry-basis mixing, aeration that wets cool grain, case-hardened wet cores, and grain engulfment and dust explosion as first-class failure modes.
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Think and work like an expert Agroecologist. Use when a task calls for Agroecologist judgment. Reasons from socio-ecological farm systems, functional diversity, soil-biology-mediated fertility, and yield-service trade-offs through mother-baby and mixed-model trials, N/P/C mass balances, PLFA/amplicon and pollinator surveys, and NDVI/FRAGSTATS landscape analysis, while treating edge-effect and plot-size artifacts, weather-year confounding, surface-only soil carbon, and ignored labor/tenure adoption constraints as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry. Use this skill whenever you are evaluating AI for scientific discovery, tackling "root node" problems, designing reinforcement learning systems, or discussing AGI timelines, safety, and global governance. Reach for it when the user faces massive combinatorial search spaces, wants to apply AI to physical/biological sciences (like digital biology), or needs to balance rapid AI scaling with the rigorous scientific method. Apply these mental models to shift the focus from building consumer apps to using AI as the ultimate meta-solution for understanding reality.
日本語の概要は準備中です。原文の説明を表示しています。
Use when a task needs the judgment of a Chemical Plant and System Operator — reconciling a batch's mass balance to catch a leak or unaccounted reaction that individually normal readings would miss, responding to an early exotherm temperature trend before it accelerates, prioritizing simultaneous alarms by consequence severity rather than order of occurrence, or flagging a combination of near-limit variables that no single-variable check would catch.
日本語の概要は準備中です。原文の説明を表示しています。
Use when a task needs the judgment of a Chemical Engineer — closing a mass/energy balance around a reactor or separation unit, evaluating scale-up risk from bench to pilot to plant, reviewing a HAZOP finding or LOPA scenario for a covered process, sizing relief for a runaway-reaction or fire case, or checking a process safety information (PSI) package against OSHA 1910.119 before startup.
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Use when a task needs the judgment of an agricultural engineer — sizing a center-pivot or drip irrigation system's peak capacity against crop water demand, computing lateral grain-bin wall pressure with Janssen's equation, sizing a waterway or tile-drainage system with Manning's equation and an NRCS design-storm return period, or building a manure/nutrient first-year availability mass balance against a crop's N requirement.
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Designs and analyzes stable-isotope-resolved metabolomics (SIRM / isotope tracing / fluxomics) experiments that measure metabolic ACTIVITY via 13C/15N/2H tracers, distinct from steady-state pool profiling. Covers tracer choice, isotopologue vs isotopomer, mass-isotopomer distributions (MID), fractional enrichment, the mandatory natural-abundance + tracer-purity correction (IsoCor, AccuCor), and the metabolic/isotopic steady-state vs non-stationary (INST-MFA) distinction. Use when feeding a labeled tracer and interpreting labeling patterns, correcting raw isotopologue intensities, computing or plotting an MID, or deciding tracing vs abundance profiling. For absolute pool concentration and MRM mechanics see metabolomics/targeted-analysis; for constraint-based genome-scale flux (FBA, not empirical tracing) see systems-biology/flux-balance-analysis; for feature detection see metabolomics/xcms-preprocessing; for pathway enrichment that ignores the pool-vs-flux caveat see metabolomics/pathway-mapping.
日本語の概要は準備中です。原文の説明を表示しています。
Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.
日本語の概要は準備中です。原文の説明を表示しています。
Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.
日本語の概要は準備中です。原文の説明を表示しています。