「mutation」の検索結果

Analyzes a repository and its test suite to generate customized mutation operators tailored to the project. Use this skill when setting up mutation testing, improving test quality, or generating project-specific mutants. Considers language constructs, business logic patterns, API calls, data types, and code complexity to produce effective mutation operators that maximize test sensitivity while avoiding trivial or equivalent mutations. Generates prioritized operator sets (high/medium/low value) with impact summaries. Triggers when users ask to generate mutation operators, customize mutation testing, analyze code for mutation opportunities, or create project-specific mutants.

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Optimize test suites using mutation testing to maximize mutation kill rate with minimal tests. Use when you need to reduce test suite size while maintaining quality, identify redundant tests, improve mutation coverage, or validate test effectiveness. The skill analyzes test coverage, execution intervals, and redundancy using mutation operators, selects or generates a minimal subset of tests that maximizes mutation kill rate, and outputs an optimized test suite with detailed reports showing killed and surviving mutants. Supports multiple programming languages and mutation testing frameworks.

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Analyzes surviving mutants from mutation testing to identify why tests failed to detect them. Takes repository code, test suite, and mutation testing results as input. Identifies root causes including insufficient coverage, equivalent mutants, weak assertions, and missed edge cases. Automatically generates actionable test improvements and new test cases. Use when analyzing mutation testing results, improving test suite effectiveness, investigating low mutation scores, generating tests to kill surviving mutants, or enhancing test quality based on mutation analysis.

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Decides HOW to mutate a DAG when a node fails, quality is below threshold, or new information changes the plan. Selects from mutation strategies (add node, replace agent, fork paths, loop back, downgrade model) based on failure type, cost budget, and execution history. Activate on "DAG failed how to fix", "mutation strategy", "replan on failure", "adaptive DAG", "recovery strategy", "what to do when node fails". NOT for detecting failures (use dag-quality), executing mutations (use dag-planner), or runtime execution (use dag-runtime).

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Hardens LifeOS tests via property/mutation testing. USE WHEN harden, hardening, property test, property based testing, PBT, fast-check, mutation test, mutation testing, Stryker, CRAP score, CRAP analysis, DRY scan, jscpd, acceptance test mutation, strengthen tests, sharpen ISCs, find bugs example tests miss, universal quantified claim, shrink counterexample, what bugs am I missing, test the tests, test of the test. NOT FOR writing new feature tests (use bun test directly), grading agent output quality (use Evals), UI verification with real Chrome (use Interceptor), finding security vulnerabilities, or building new functionality.

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Graph-informed mutation testing triage. Parses codebases with Trailmark, runs mutation testing and necessist, then uses survived mutants, unnecessary test statements, and call graph data to identify false positives, missing test coverage, and fuzzing targets. Use when triaging survived mutants, analyzing mutation testing results, identifying test gaps, finding fuzzing targets from weak tests, running mutation frameworks (including circomvent and cairo-mutants), or using necessist.

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Mutation-driven test vector generation. Finds implementations of a cryptographic algorithm or protocol, runs mutation testing to identify escaped mutants, then generates new test vectors that deliberately exercise the uncovered code paths. Compares before/after mutation kill rates to prove vector effectiveness. Use when generating cryptographic test vectors, measuring Wycheproof coverage gaps, finding escaped mutants via mutation testing, creating cross-implementation test suites, or improving test vector coverage for crypto primitives.

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Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression. Reliably detects mutations at VAF above 0.5 percent using consensus-based approaches. Use when identifying tumor mutations from plasma DNA or tracking specific variants.

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Build OncoPrint and co-mutation matrix plots from somatic-variant cohorts using ComplexHeatmap, maftools, and comut.py with alteration-type stacking, sample ordering by mutational burden, mutual-exclusivity overlays, and clinical annotation tracks. Use when visualizing per-sample mutation patterns across recurrent driver genes, comparing alteration classes, or identifying mutually-exclusive / co-occurring driver pairs.

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Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression. Reliably detects mutations at VAF above 0.5 percent using consensus-based approaches. Use when identifying tumor mutations from plasma DNA or tracking specific variants.

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Expert guide for property-based testing (fast-check, Hypothesis) and mutation testing (Stryker, mutmut) — AI-generated test properties, invariant discovery, mutation score optimization, and test suite quality verification / Panduan ahli property-based testing (fast-check, Hypothesis) dan mutation testing (Stryker, mutmut) — properti tes yang dihasilkan AI, penemuan invarian, optimasi skor mutasi, dan verifikasi kualitas suite tes.

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Build OncoPrint and co-mutation matrix plots from somatic-variant cohorts using ComplexHeatmap, maftools, and comut.py with alteration-type stacking, sample ordering by mutational burden, mutual-exclusivity overlays, and clinical annotation tracks. Use when visualizing per-sample mutation patterns across recurrent driver genes, comparing alteration classes, or identifying mutually-exclusive / co-occurring driver pairs.

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Use this skill when implementing form submissions, data mutations, or any 'use server' function in Next.js 16. Trigger words: フォーム送信, mutation, 更新処理, 保存, Server Action, use server, useActionState, revalidatePath, データ更新.

Build OncoPrint and co-mutation matrix plots from somatic-variant cohorts using ComplexHeatmap, maftools, and comut.py with alteration-type stacking, sample ordering by mutational burden, mutual-exclusivity overlays, and clinical annotation tracks. Use when visualizing per-sample mutation patterns across recurrent driver genes, comparing alteration classes, or identifying mutually-exclusive / co-occurring driver pairs.

日本語の概要は準備中です。原文の説明を表示しています。

Build OncoPrint and co-mutation matrix plots from somatic-variant cohorts using ComplexHeatmap, maftools, and comut.py with alteration-type stacking, sample ordering by mutational burden, mutual-exclusivity overlays, and clinical annotation tracks. Use when visualizing per-sample mutation patterns across recurrent driver genes, comparing alteration classes, or identifying mutually-exclusive / co-occurring driver pairs.

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Decides HOW to mutate a DAG when a node fails, quality is below threshold, or new information changes the plan. Selects from mutation strategies (add node, replace agent, fork paths, loop back, downgrade model) based on failure type, cost budget, and execution history. Activate on "DAG failed how to fix", "mutation strategy", "replan on failure", "adaptive DAG", "recovery strategy", "what to do when node fails". NOT for detecting failures (use dag-quality), executing mutations (use dag-planner), or runtime execution (use dag-runtime).

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Configures mewt or muton campaigns, analyzes surviving mutants, and investigates bugs exposed by testing gaps. Use when setting up mutation testing, reviewing campaign results, identifying equivalent mutants, or finding bugs from surviving mutations.

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Governs how the OpenBot browser app reads and writes server data — every request goes through `client` in app/src/lib/client.ts, every read is a queryOptions factory in app/src/lib/<entity>/queries.ts, every write is a mutationOptions factory in app/src/lib/<entity>/mutations.ts, and components consume them through useQuery/useMutation. Use when adding or changing a screen that loads server data, calling a /api/... endpoint from the browser, adding a query key, writing a create/update/delete flow, deciding where a fetch belongs, or reviewing a diff that contains the word fetch under app/src. Don't use for server-side route handlers under server/ (that is not browser code), for form validation schemas (those live in lib/<entity>/form.ts), for page layout and Item rows, or for the AG-UI stream itself, which the runtime carries rather than the client.

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Pseudo-mutation analysis ONLY: answer whether tests would catch a bug if production code changed, which meaningful changes would still pass, or which caller-visible mutations existing assertions would miss; verify candidates when requested, then optionally close verified gaps. Includes explicit read-only per-test composition for grading. Activate for behavioral blind spots tied to production behavior. Polyglot. DO NOT USE FOR: suite taxonomy, metadata, or distribution reports (test-tagging); .NET line-vs-branch or Cobertura interpretation, arithmetic, plateaus, project-wide coverage gaps, or coverage-backed test/CRAP priorities (coverage-analysis; use native coverage tooling outside .NET); named-target CRAP (crap-score); new suites (code-testing); assertion/smell audits; or mutation tools.

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Hunt fintech-specific GraphQL vulnerabilities: money-movement mutations (transfers, redemptions, withdrawals, card top-ups), ledger/balance/portfolio query IDOR, decimal-precision and rounding abuse, idempotency-key bypass enabling double-spend, KYC/PII field-level authorization gaps, and admin-override mutations reachable via mass assignment. Distinct from hunt-graphql, which owns generic GraphQL discovery and IDOR/mutation methodology — this skill owns the delta introduced when a GraphQL layer sits in front of a ledger, wallet, payments, banking, brokerage, or lending backend, where a resolver bug moves real money instead of just leaking data. Use when hunting a fintech, banking, payments, wallet, neobank, brokerage, or lending target that exposes a GraphQL API, or when a schema/response includes balance, transfer, ledger, redeem, quote, KYC, or account-linking fields.

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Tests whether two genomic interval sets overlap (colocalize) more than expected by chance using a permutation test against a structured-genome null model. Covers bedtools fisher (analytic 2x2 screen), bedtools shuffle + jaccard permutation, GAT (isochore/GC-conditioned simulation with FDR), regioneR (flexible permutation, randomizeRegions vs circularRandomizeRegions, localZScore), LOLA (universe-relative Fisher against a region database), and GREAT/rGREAT (regulatory-domain binomial + hypergeometric for ontology-from-regions). Stresses the universe/background choice, matched background, blacklist exclusion, and multiple-testing control. Use when asking whether peaks/regions are enriched at enhancers/TFBS/features, scoring region-set colocalization or region-set enrichment, comparing CNV/SV concordance, or turning an overlap count into a defensible p-value.

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Detects somatic mutations in circulating tumor DNA, treating low-VAF detection as a signal-versus-noise problem set by error suppression and molecules sampled, not by the choice of caller. Distinguishes de novo CALLING (scanning a panel for unknown variants, bounded by per-locus error and multiple testing) from tumor-informed DETECTION (tracking a pre-specified variant set, where panel integration reaches single-ppm). Covers VarDict and Mutect2 for de novo calling, UMI-aware callers, and a pysam-based known-variant VAF tracker, with matched-WBC subtraction as the mandatory defense against clonal hematopoiesis (the dominant false positive). Use when calling or tracking tumor mutations from plasma cfDNA, setting a VAF threshold, or deciding whether a low-VAF call is tumor versus CHIP.

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Detects acquired antimicrobial-resistance determinants and chromosomal point-mutation resistance in bacterial assemblies using AMRFinderPlus, ResFinder 4.0 (acquired + PointFinder), CARD-RGI, abritAMR, staramr, and species-specific callers (TB-Profiler, Mykrobe). Harmonises cross-tool output via hAMRonization, contextualises determinants with mobile-genetic-element annotation (MOB-suite, PlasmidFinder, MobileElementFinder, ICEberg), predicts phenotype against EUCAST or CLSI breakpoints, and translates calls into WHO GLASS reporting categories. Use when screening clinical or surveillance isolates for AMR, distinguishing acquired vs intrinsic vs point-mutation resistance, calling rpoB / katG / pncA / gyrA / mgrB mutations, reconciling AMRFinderPlus vs RGI vs ResFinder disagreement, contextualising carbapenemases or mcr alleles on plasmids, predicting susceptibility from genotype against the WHO Mtb 2nd-edition catalogue, or building a hAMRonized multi-lab AMR surveillance pipeline.

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Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools, g3-lollipop, trackViewer, and ProteinPaint. Use when visualizing recurrent mutation hotspots on a single gene's protein, marking domain boundaries from UniProt/Pfam, comparing missense vs truncating distributions, or contrasting two cohorts on the same lollipop.

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