「reversibility」の検索結果

Run the worst-case drill before an agent goes autonomous — the 'if this agent were fully hijacked right now, what's the damage' walk-through, the containment controls (caps, kill-switch, reversibility, isolation), and the recovery plan. Use when asked what's the worst my agent could do, run a blast-radius assessment, prepare for an agent going rogue, or am I ready to let this run unattended. Produces the worst-case walk-through, the containment controls, the reversibility audit, and the incident-recovery runbook.

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Assesses decision reversibility and risk at critical checkpoints. Use when a workflow reaches a high-stakes branch needing escalation check.

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Convenes a multi-LLM expert panel to pressure-test hard-to-reverse decisions. Use when reversibility score is low and adversarial review is warranted.

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Technical decision-making frameworks - trade-off evaluation, reversibility analysis, and second-order thinking for better engineering choicesUse when "should we, which is better, trade-off, decision, choose between, versus, pros and cons, what if we, is it worth, evaluate options, decisions, trade-offs, architecture, adr, reversibility, strategy, planning, risk" mentioned.

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Classify decisions as Hat/Haircut/Tattoo by reversibility. Use to calibrate how much analysis a decision deserves.

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Draft a PR body from OMC's paper trail — the smallest visual that proves the change, evidence consumed from the verify protocol (never re-collected), reversibility from the ADR test on the diff, glossary language throughout.

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Apply meta-principles of software craftsmanship: DRY, orthogonality, tracer bullets, and design by contract. Use when the user mentions "best practices", "pragmatic approach", "broken windows", "tracer bullet", "software craftsmanship", "avoid technical debt", "code ownership", or "how do I become a better developer". Also trigger when evaluating build-vs-buy decisions, designing estimation approaches, or choosing between reversible and irreversible architectural decisions. Covers estimation, domain languages, and reversibility. For code-level quality, see clean-code. For refactoring techniques, see refactoring-patterns.

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Use when the reflex is to add a feature, layer, or process. Prefer removing harmful or nonessential elements first, with an irreversibility guard before deletion.

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Before heavy deliberation, classify the decision as cheap or costly to undo; decide two-way doors fast and stage one-way doors to preserve options.

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Designs covalent inhibitors and warheads targeting cysteine, lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.

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Turns a hard product or career decision into a one-page decision memo with the eigenquestion, options, pre-mortem with kill criteria, reversibility rating, a named decider and a review date. Use when you ask 'how should we decide', 'should we build or kill this', 'one-way door or two-way door', 'run a pre-mortem', 'we keep going in circles', 'quit or pivot', or want to grade a decision doc. Draws on 396 insights from 177 Lenny's Podcast guests, led by Annie Duke, Shreyas Doshi and Shishir Mehrotra.

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Deliberate-choice procedure for a medium-to-high-stakes engineering fork — when the first plausible solution (the instinct, the default next-token pull) would be costly to get wrong. Fires AUTONOMOUSLY: invoke proactively whenever a fork fits, never wait to be asked — mechanical triggers include a fix failing for the 2nd-3rd time, adding a dependency, schema/migration design, deleting or deprecating things others depend on, changing a public API, choosing an architecture or stack. Refuse the premature collapse: hold real options open (urge · contrarian · synthesis · out-of-box · intuitive dots · precedent · first-principles), ground each branch in at least one fact from outside the model (codebase, docs, benchmark, spike), future-model consequences (blast radius, reversibility, maintenance, pre-mortem), collapse by deliberate choice, then try to refute the winner before acting. Log the decision and rejected branches in docs/decision_logs/. Not for routine calls — a decision worth more than one forward pass.

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Classifies agent tasks into 4 risk tiers (GREEN/YELLOW/RED/CRITICAL). Use when assessing action reversibility before committing to an approach.

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Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.

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Expert in decision-making frameworks - systematic approaches to making better decisions under uncertainty. Covers decision criteria, reversibility assessment, stakeholder alignment, and decision documentation. Knows when to decide fast and when to deliberate. Use when "decision framework, how to decide, making a choice, tradeoff, should we, pros and cons, decision matrix, weighing options, " mentioned.

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Pipeline retirement protocol for completed work items. Implements a 7-stage validate-commit-push-submit-notify-cleanup-terminate pipeline with irreversibility after push. Done means gone.

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Use when the user faces a real decision with stakes and wants it framed cleanly — options, ranked criteria, a recommendation, the falsifier, and reversibility — then logged to decisions/log.md. Trigger on "/decide", "help me decide", "should I X or Y", "frame this decision", "what's the call here", "log this decision".

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**WORKFLOW SKILL** — Risk awareness before action. USE FOR: assessing risks (security, data integrity, compatibility, operational, reversibility) of any task at variable depth. Accepts weight: Light (quick scan), Standard (dimensional analysis), Deep (full Risk Radar with evidence). Can be invoked multiple times in the same flow with increasing weight. DO NOT USE FOR: penetration testing, compliance audits, static security analysis tools.

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Prospective failure imagination for a plan, decision, or running system. Operates in two modes — **plan mode** (a plan has not yet been committed to; imagine its catastrophic failure broadly) and **scenario mode** (a specific catastrophic scenario is posed against an existing system; investigate causes against the actual code and architecture). Spawns parallel pre-mortemers in isolation across three categories of lens: standard failure classes (technical, operational, estimation, scope, adoption, dependency, team, incentive, detection, reversibility, adversarial), 0-3 ad-hoc target-specific lenses the orchestrator names when warranted, and a first-principles lens that always runs to catch what the prescribed taxonomy misses. Synthesizes into a prioritized risk register with early-warning signals. Produces feedback only — no code, no tickets, no artifacts.

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Designs covalent inhibitors and warheads targeting cysteine, lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.

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Use for tradeoff analysis, or when the user must pick between concrete options: "A or B?", "which library should we use?", "build vs buy", "compare these approaches". Scores options on weighted criteria, tests sensitivity and reversibility. Skip for open ideation or single-option reviews.

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Continuous environmental scanning across six PESTEL categories — Political, Economic, Social, Technological, Environmental, Legal. Not a one-time analysis but an ongoing radar. Three modes. Diagnostic mode runs a full scan and prioritises forces by impact, speed, and reversibility. Review mode checks the watch list monthly for movement and new signals. Alert mode defines concrete monitoring triggers for each top force. Use whenever someone wants to understand external forces acting on their business, assess macro risk, prepare for planning, or check whether the world has moved since last time they looked. Connects to the strategy map (forces act on the chain) and Wardley Map (forces drive component evolution). Based on practice by Eterdis (eterdis.com).

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Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.

日本語の概要は準備中です。原文の説明を表示しています。

Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.

日本語の概要は準備中です。原文の説明を表示しています。