「significance」の検索結果

Query ClinVar for clinical variant significance. Use when user asks about variant pathogenicity, genetic variants, clinical significance, or disease-causing mutations. Triggers on "clinvar", "pathogenic", "variant significance", "clinical significance", "disease variant", "mutation pathogenicity".

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Guide for annotating statistical significance (p-value asterisks) on comparison plots. Covers standard notation (ns, *, **, ***, ****), matplotlib bracket+asterisk implementation, and use with seaborn box/violin/bar plots. Use when preparing publication-ready figures with significance markers.

日本語の概要は準備中です。原文の説明を表示しています。

Diagnoses bias, anomalies, and strange-looking results on a specific PostHog experiment. Covers empty / 0-exposure experiments, sample ratio mismatch, identity fragmentation, multi-variant exposure, uneven-split exclusion bias, significance traps (peeking, A/A, Bayesian vs Frequentist), PostHog-vs-SQL discrepancies, and surprises after mid-run edits. Symptom-driven dispatch to the right diagnostic. TRIGGER when: user asks 'is my experiment biased?' or 'why 0 exposures?', references the bias banner, says a variant looks strange / wrong / off, sees significance flipping, notices PostHog numbers disagreeing with their SQL, sees an A/A test showing significance, or reports surprises after mid-run edits. DO NOT TRIGGER when: creating a new experiment (use creating-experiments), only configuring rollout (use configuring-experiment-rollout) or metrics (use configuring-experiment-analytics), or only asking lifecycle questions (use managing-experiment-lifecycle).

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Analyze A/B test results with statistical significance, sample size validation, confidence intervals, and ship/extend/stop recommendations. Use when evaluating experiment results, checking if a test reached significance, interpreting split test data, or deciding whether to ship a variant.

日本語の概要は準備中です。原文の説明を表示しています。

Statistical significance calculator for A/B test results with sample size requirements, segment breakdowns, and hypothesis generation. Use when feeding test results, checking statistical significance, calculating sample sizes, analyzing experiment outcomes, or generating next test ideas based on results. Platform: Google and Meta.

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Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.

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Design, plan, and analyze A/B tests with statistical rigor. Use when the user asks about A/B testing, split testing, experiment design, statistical significance, sample size calculation, test duration, multivariate testing, or conversion experiments. Trigger phrases include "A/B test", "split test", "experiment", "statistical significance", "sample size", "test duration", "which version wins", "conversion experiment", "hypothesis test", "variant testing".

日本語の概要は準備中です。原文の説明を表示しています。

A/B and multivariate testing methodology. Design experiments, calculate sample sizes, determine statistical significance, avoid common pitfalls, and interpret results. Platform-agnostic framework applicable to landing pages, emails, ads, pricing, and product features. Use when the user asks about A/B testing, split testing, experiment design, statistical significance, or conversion experiments.

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Analyze A/B test results — statistical significance, practical significance, and segmentation. Use when asked to "analyze our A/B test", "is this result significant", or "read these experiment results".

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Design and execute A/B tests for ML models in production using traffic splitting, statistical significance testing, and canary/shadow deployment strategies. Measure performance differences and make data-driven decisions about model rollout. Use when validating a new model version before full rollout, comparing candidate models trained with different algorithms, measuring business metric impact of model changes, or when regulatory requirements mandate gradual rollout.

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Guide for annotating ENCODE regulatory variants with ClinVar clinical significance. Use when users need to check if variants in ENCODE peaks have clinical associations, find pathogenic variants in regulatory regions, or assess variant clinical impact. Trigger on: ClinVar, clinical significance, pathogenic variant, variant classification, clinical variant, disease variant, VUS, benign, likely pathogenic.

日本語の概要は準備中です。原文の説明を表示しています。

A/B testing specialist v3 — hypothesis, sample size, statistical significance, Bayesian

日本語の概要は準備中です。原文の説明を表示しています。

Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.

日本語の概要は準備中です。原文の説明を表示しています。

Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze A/B test results for statistical significance with ship, extend, or kill recommendations

日本語の概要は準備中です。原文の説明を表示しています。

When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program. Also use when the user mentions "A/B test," "split test," "experiment," "test this change," "variant copy," "multivariate test," "hypothesis," "should I test this," "which version is better," "test two versions," "statistical significance," "how long should I run this test," "growth experiments," "experiment velocity," "experiment backlog," "ICE score," "experimentation program," or "experiment playbook." Use this whenever someone is comparing two approaches and wants to measure which performs better, or when they want to build a systematic experimentation practice. For tracking implementation, see analytics. For page-level conversion optimization, see cro.

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Provide evidence-grounded mock peer review of scientific manuscripts or excerpts, covering significance, validity, and major/minor concerns. Use for 模拟审稿、投稿前自审、审稿人视角评估; not author rebuttal drafting.

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Apply statistical methods including descriptive stats, trend analysis, outlier detection, and hypothesis testing. Use when analyzing distributions, testing for significance, detecting anomalies, computing correlations, or interpreting statistical results.

日本語の概要は準備中です。原文の説明を表示しています。

When the user wants to plan, design, or implement an A/B test or experiment. Also use when the user mentions "A/B test," "split test," "experiment," "test this change," "variant copy," "multivariate test," "hypothesis," "conversion experiment," "statistical significance," or "test this." For tracking implementation, see analytics-tracking.

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Design and evaluate paid-ad experiments with hypotheses, randomization units, sample-size and duration assumptions, guardrails, platform experiment tools, analysis, and decision rules. Use for A/B test, split test, experiment design, hypothesis, statistical significance, sample size, test duration, or experiment readout.

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Build or update a chronology from declared document sources and uploads — dated events extracted, de-duped, and tagged by significance per the matter theory. Use when the user asks to build a chronology or timeline from a production or matter file, says "chron from the production" or "what happened when", or needs a working, statement-of-facts, or witness-specific timeline.

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This skill should be used when the user asks to "analyze experimental results", "run strict statistical analysis", "compare model performance", "generate scientific figures", "check significance", "do ablation analysis", or mentions interpreting experiment data with rigorous statistics and visualization. It focuses on strict analysis bundles, not Results-section prose.

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Meta-skill for publication-ready figures. Use when creating journal submission figures requiring multi-panel layouts, significance annotations, error bars, colorblind-safe palettes, and specific journal formatting (Nature, Science, Cell). Orchestrates matplotlib/seaborn/plotly with publication styles. For quick exploration use seaborn or plotly directly.

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Run regression analysis (OLS or logistic) on uploaded CSV/Excel data, generating coefficients, R², p-values, VIF, and plain-language interpretation. Triggered by requests for regression modeling, fitting data, testing significance, checking multicollinearity, or keywords like OLS, logit, coefficient, p-value, or R-squared.

日本語の概要は準備中です。原文の説明を表示しています。