「t cells」の検索結果

Expert-level electrochemistry knowledge. Use when working with electrochemical cells, electrode potentials, Nernst equation, electrolysis, batteries, fuel cells, corrosion, electroplating, or electroanalytical methods. Also use when the user mentions 'galvanic cell', 'electrolytic cell', 'electrode potential', 'Nernst equation', 'overpotential', 'Butler-Volmer', 'battery', 'fuel cell', 'corrosion', 'electroplating', 'cyclic voltammetry', or 'impedance spectroscopy'.

日本語の概要は準備中です。原文の説明を表示しています。

Create iMandalArt 2.2 pure-text 3x3 Mandala index cards with a five-character center axis, eight orthogonal surrounding angles labeled Ⓐ-Ⓗ, compact title cells such as Ⓐ健康復節, hard-line CJK layout, optional の字型 ordering, and 井字號 compass ordering. Use when the user asks for iMandalArt, iMandalart, I MandalArt, の字型, ◊字型, 井字號, 中國城市方位, 64＋8＋1, 手機方形曼陀羅, 正方形九宮索引卡, 五字定格, ◎中心, Ⓐ-Ⓗ 九宮卡, TheBrain/Cerebro preview-safe hard-line cards, or a square 3x3 card that is not a Markdown table, visible-border PE2 card, or 81-cell Mandala.

Create game-ready fixed-cell pixel-art character spritesheets from text concepts, reference images, or existing character art. Use when Codex needs to design, generate, clean up, validate, and package 2D game characters with native 32x32, 64x64, or 128x128 cells; 4-way or 8-way directions; idle, walk/run, jump, attack, archer, caster, or other animation strips; transparent GIF/WebP previews; and per-direction targeted regeneration.

日本語の概要は準備中です。原文の説明を表示しています。

Build the deterministic evidence ledger (artifact_manifest.json + claims.json) that every other Anti-Autoresearch auditor reads. One pass inventories artifacts, derives the observability level (L0 PDF-only / L1 +LaTeX / L2 +repo+results) by fixed rule, and extracts span-anchored, hashed, checkable claims (numbers, comparisons, scope, method, baselines, citations, captions, table cells) into claims.json. An OPTIONAL additive cross-model pass ADDS span-anchored semantic claims — method, theorem statements with their assumptions, definitions, proof/derivation steps and equations, scope, baselines, conclusions, the motivation span, and reproducibility-artifact references (the proof, derivation, and structure anchors the family B/D/G auditors need) — it never invents a number, emits a finding, or computes a verdict. Run FIRST, before any audit skill. Triggers: "build the ledger", "extract claims", "prep for integrity audit", "evidence ledger", "建证据账本".

日本語の概要は準備中です。原文の説明を表示しています。

Sort, hide, show, reorder, resize, pin, format, and color-code columns in a Datagrok TableView grid via the datagrok_exec tool. Use whenever the user asks to sort by a column (any direction), multi-sort, hide / show / reorder / pin / resize columns, freeze the first N columns, change number-format display, color-code cells (defaults and grid-only tint here; full per-type reference in datagrok-df-and-columns), set row height, or reset the grid back to defaults. Distinct from datagrok-df-and-columns (which owns column-level data metadata like semType, units, friendlyName, and is also where canonical color-coding lives) and from datagrok-viewers (which owns scatter plot / histogram / etc.). Does NOT cover filtering (`datagrok-filtering`), selection (`datagrok-selection`), custom cell renderer authoring (`create-cell-renderer`), saving / restoring layouts, or grid event handlers.

日本語の概要は準備中です。原文の説明を表示しています。

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

日本語の概要は準備中です。原文の説明を表示しています。

Feishuのクラウド文書を読み取り、段落の修正や追記、表の編集、新規作成を支援します。文書内の構造を確認し、画像やファイルのアップロードも扱います。

• 共有されたFeishu文書を読みたいとき
• 段落の修正や指定位置への挿入
• 新規文書の作成と本文入力

Keep a Markdown table readable in a narrow terminal of about 100 display columns - a wide table or one carrying prose in its cells wraps into unreadable ragged rows. Always call read_skill for bundled:table-fit before emitting a Markdown table in a final answer, and load it as soon as the answer starts forming as a comparison, a mapping, a feature matrix, a pros-and-cons, an options rundown, or a per-item summary across several dimensions. Do not load it for a table already inside a file being edited, for code, data, or test fixtures that merely look tabular, for tables the user pasted for you to read, or for an answer with no table and no tabular shape forming.

日本語の概要は準備中です。原文の説明を表示しています。

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

日本語の概要は準備中です。原文の説明を表示しています。

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

日本語の概要は準備中です。原文の説明を表示しています。

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

日本語の概要は準備中です。原文の説明を表示しています。

Audit a local or remote tabular file (CSV/TSV) for common data quality issues — schema, nulls, types, duplicates. Read-only. Use when a dataset needs a quality check before publishing, or a showcase renders wrong (blank cells, garbled numbers, an unsortable date column) and the cause needs isolating.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes single-cell pooled CRISPR screens (Perturb-seq, CROP-seq, Perturb-CITE-seq, ECCITE-seq, multiome) where each cell carries an sgRNA and a scRNA-seq / surface-protein / chromatin readout. Covers experimental design (direct-capture Perturb-seq Dixit 2016 vs CROP-seq 3'UTR-barcoded Datlinger 2017 vs ECCITE-seq vs Multiome), MOI for sgRNA assignment, escaper-cell filtering (Mixscape, Papalexi 2021), SCEPTRE NB GLM + permutation for low-MOI (Barry 2024 Genome Biol 25:124), the Pertpy framework, factor decomposition, genome-scale Perturb-seq (Replogle 2022 Cell, 2.5M cells), and per-perturbation single-cell DE. Use when running a single-cell CRISPR screen, choosing direct-capture vs CROP-seq architecture, filtering escaper cells, performing single-cell DE, integrating Perturb-seq with pathway analysis, scaling to GW CRISPRi via Replogle protocol, or analyzing multi-omics screens.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes single-cell pooled CRISPR screens (Perturb-seq, CROP-seq, Perturb-CITE-seq, ECCITE-seq, multiome) where each cell carries an sgRNA and a scRNA-seq / surface-protein / chromatin readout. Covers experimental design (direct-capture Perturb-seq Dixit 2016 vs CROP-seq 3'UTR-barcoded Datlinger 2017 vs ECCITE-seq vs Multiome), MOI for sgRNA assignment, escaper-cell filtering (Mixscape, Papalexi 2021), SCEPTRE NB GLM + permutation for low-MOI (Barry 2024 Genome Biol 25:124), the Pertpy framework, factor decomposition, genome-scale Perturb-seq (Replogle 2022 Cell, 2.5M cells), and per-perturbation single-cell DE. Use when running a single-cell CRISPR screen, choosing direct-capture vs CROP-seq architecture, filtering escaper cells, performing single-cell DE, integrating Perturb-seq with pathway analysis, scaling to GW CRISPRi via Replogle protocol, or analyzing multi-omics screens.

日本語の概要は準備中です。原文の説明を表示しています。

Load this skill whenever the project contains HTML data tables (<table> elements). Under no circumstances use tables for layout purposes. Absolutely always include <th> elements with appropriate scope attributes, a <caption> or aria-labelledby, and ensure complex tables have headers associated with data cells. Apply these rules to every data table without exception.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes single-cell pooled CRISPR screens (Perturb-seq, CROP-seq, Perturb-CITE-seq, ECCITE-seq, multiome) where each cell carries an sgRNA and a scRNA-seq / surface-protein / chromatin readout. Covers experimental design (direct-capture Perturb-seq Dixit 2016 vs CROP-seq 3'UTR-barcoded Datlinger 2017 vs ECCITE-seq vs Multiome), MOI for sgRNA assignment, escaper-cell filtering (Mixscape, Papalexi 2021), SCEPTRE NB GLM + permutation for low-MOI (Barry 2024 Genome Biol 25:124), the Pertpy framework, factor decomposition, genome-scale Perturb-seq (Replogle 2022 Cell, 2.5M cells), and per-perturbation single-cell DE. Use when running a single-cell CRISPR screen, choosing direct-capture vs CROP-seq architecture, filtering escaper cells, performing single-cell DE, integrating Perturb-seq with pathway analysis, scaling to GW CRISPRi via Replogle protocol, or analyzing multi-omics screens.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes single-cell pooled CRISPR screens (Perturb-seq, CROP-seq, Perturb-CITE-seq, ECCITE-seq, multiome) where each cell carries an sgRNA and a scRNA-seq / surface-protein / chromatin readout. Covers experimental design (direct-capture Perturb-seq Dixit 2016 vs CROP-seq 3'UTR-barcoded Datlinger 2017 vs ECCITE-seq vs Multiome), MOI for sgRNA assignment, escaper-cell filtering (Mixscape, Papalexi 2021), SCEPTRE NB GLM + permutation for low-MOI (Barry 2024 Genome Biol 25:124), the Pertpy framework, factor decomposition, genome-scale Perturb-seq (Replogle 2022 Cell, 2.5M cells), and per-perturbation single-cell DE. Use when running a single-cell CRISPR screen, choosing direct-capture vs CROP-seq architecture, filtering escaper cells, performing single-cell DE, integrating Perturb-seq with pathway analysis, scaling to GW CRISPRi via Replogle protocol, or analyzing multi-omics screens.

日本語の概要は準備中です。原文の説明を表示しています。

Turns reported data problems (messages, tickets, meeting notes, complaints) into one DRAFT issue log: one row per issue with the symptom as reported, dataset and fields named, reproduction steps, affected reports, first seen date, reporters, a suggested owner, and blank severity, root cause and status cells for the owner. Never asserts a root cause, severity or fix. Use when the user asks to "log these data issues", "turn these complaints about the numbers into an issue list", "build the data quality backlog", "which reports are hit by this data problem" or "write up the reproduction steps for this data bug". Do not use for exploring or profiling a dataset, use dataset-insight-pack instead; for an IT incident write-up, use incident-postmortem-drafter; for tracking fix actions once assigned, use corrective-action-tracker. Drafts for human review; never approves, authorises or signs off.

日本語の概要は準備中です。原文の説明を表示しています。

Read Microsoft Excel (.xlsx) files robustly with `openpyxl` (or `pandas`). Covers multi-sheet workbooks, header rows, empty cells, merged cells, comma-separated list cells, and converting a sheet to a list-of-dicts the rest of your code can consume. Use when a task input or reference document is an `.xlsx` file rather than JSON/CSV.

日本語の概要は準備中です。原文の説明を表示しています。

Designs donor/repair templates for precise CRISPR knock-ins -- choosing the format (ssODN, long-ssDNA/Easi-CRISPR, dsDNA/plasmid, AAV6), sizing homology arms, placing the cut within ~10 bp of the edit, and adding a mandatory codon-checked blocking (PAM/seed) mutation so the edited allele is not re-cut. Frames the HDR-vs-NHEJ-vs-MMEJ pathway competition, the MMEJ (PITCh) and homology-independent (HITI/HMEJ) alternatives for post-mitotic cells, ssODN strand/asymmetry choice, phosphorothioate end-protection, and ranked HDR enhancers. Use when designing a donor for a point mutation, epitope/fluorophore tag, allele replacement, or knock-in, or when HDR efficiency is low. Guide design and base/prime editing are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Expert-level tissue engineering covering scaffold design, cell culture, bioreactors, stem cells, vascularization, and clinical translation of engineered tissues.

日本語の概要は準備中です。原文の説明を表示しています。

Designs donor/repair templates for precise CRISPR knock-ins -- choosing the format (ssODN, long-ssDNA/Easi-CRISPR, dsDNA/plasmid, AAV6), sizing homology arms, placing the cut within ~10 bp of the edit, and adding a mandatory codon-checked blocking (PAM/seed) mutation so the edited allele is not re-cut. Frames the HDR-vs-NHEJ-vs-MMEJ pathway competition, the MMEJ (PITCh) and homology-independent (HITI/HMEJ) alternatives for post-mitotic cells, ssODN strand/asymmetry choice, phosphorothioate end-protection, and ranked HDR enhancers. Use when designing a donor for a point mutation, epitope/fluorophore tag, allele replacement, or knock-in, or when HDR efficiency is low. Guide design and base/prime editing are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Designs donor/repair templates for precise CRISPR knock-ins -- choosing the format (ssODN, long-ssDNA/Easi-CRISPR, dsDNA/plasmid, AAV6), sizing homology arms, placing the cut within ~10 bp of the edit, and adding a mandatory codon-checked blocking (PAM/seed) mutation so the edited allele is not re-cut. Frames the HDR-vs-NHEJ-vs-MMEJ pathway competition, the MMEJ (PITCh) and homology-independent (HITI/HMEJ) alternatives for post-mitotic cells, ssODN strand/asymmetry choice, phosphorothioate end-protection, and ranked HDR enhancers. Use when designing a donor for a point mutation, epitope/fluorophore tag, allele replacement, or knock-in, or when HDR efficiency is low. Guide design and base/prime editing are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Chemical equilibrium, chemical kinetics, and electrochemistry — the quantitative core of physical chemistry. Covers equilibrium constants (Keq, Kc, Kp), Le Chatelier's principle, ICE tables, buffers and the Henderson-Hasselbalch equation, solubility product (Ksp) and the common-ion effect, rate laws, reaction order, integrated rate laws, half-life, the Arrhenius equation and activation energy, catalysis, redox reactions, galvanic and electrolytic cells, standard cell potentials, and the Nernst equation. Use when solving quantitative problems about how far a reaction goes (equilibrium), how fast it goes (kinetics), or how it converts chemical energy to electrical energy (electrochemistry).

日本語の概要は準備中です。原文の説明を表示しています。