数据与 AI技能

Produce 3D assets with Tripo (tripo3d.ai / Tripo AI by VAST) through its OpenAPI and Studio platform — text-to-3D, image-to-3D, and multiview-to-3D generation; PBR texturing; auto-rigging and preset animation; retopology/low-poly and quad remesh; format conversion (GLB/FBX/OBJ/USDZ/STL/3MF) and engine import (Unity/Unreal/Blender/3D printing). Use when an agent must drive the async task-based Tripo API (create task, poll or webhook, download), choose a model version (v3.0 / v3.1 / P1), write prompts or prepare input images, control mesh/texture parameters, estimate credits and respect rate limits, review generated mesh quality (topology, UVs, poly count, texture fidelity), run iteration and repair workflows, or reason about the rights/licensing of Tripo-generated assets. Trigger on requests to generate, texture, rig, animate, retopologize, convert, or evaluate a 3D model with Tripo, or to integrate the Tripo API into a pipeline. Not for choosing a 3D renderer, editing meshes by hand, or non-Tripo generators.

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Provider-independent workflow for producing terminal, IDE, documentation, browser, desktop, and application demonstration videos. Use when choosing authentic capture, browser automation, synthetic UI, or hybrid treatment; scripting actions and narration; resetting demo state; protecting secrets and personal data; directing cursor/callouts; creating crop variants; and reviewing workflow truth, readability, accessibility, and provenance.

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Produce anime-style and stylized 2D animation with generative image and video tools as a craft discipline, not a filter. Use when a request asks for anime, manga-style, cel-shaded, sakuga, shonen/shojo/seinen/slice-of-life, mecha, or retro-90s-OVA animation; when planning shots, motion, and cutting rhythm to anime convention; when holding a character on-model and preventing style drift across shots or episodes; when choosing prompting vocabulary that actually controls anime look; when pairing voice, music, and impact SFX to stylized action; and when navigating the cultural, IP, and platform-policy sensitivities of AI anime (studio/artist style imitation, fan-art and IP boundaries, disclosure and monetization). This is provider-neutral; models are named only as illustrative options.

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Translate a creative brief, brand system, or reference set into an original, portable visual-direction system for image and video production. Use for art direction, reference analysis without imitation, design tokens, palette and contrast, typography, composition, texture and material, lighting, lens and camera language, motion language, cross-shot continuity, accessibility, production handoff, visual review, and repair; do not use for provider-specific API syntax or model-specific prompt recipes.

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Refresh the data tables in optimal-blog.md from master.db. Checks the data for integrity problems FIRST, then runs the generator that picks per-language winners and splices every GEN-marked table, then reconciles the surrounding prose. Use after new experiment results land, or when the optimal-blog numbers are stale.

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Experiment executor and monitor for academic research. 2-agent system covering code experiments (ML training, statistical analysis, ETL, simulation) and human studies (surveys, field studies, interviews). 4 modes: run (execute + monitor code), manage (track human studies), validate (statistical interpretation + reproducibility verification), plan (Socratic experiment design). Use when a researcher wants to run or monitor a research experiment, manage or resume a human-subject study, check the statistics or reproducibility of research results, or design an experiment or study, in English or Chinese (e.g., 跑實驗、管理研究、驗證結果、規劃實驗).

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Content-derived infographic poster — reads the source file and builds a statistical poster from the facts already in it. Not a dashboard, not a CV, not an AntV template. Uses common-scale encodings (Cleveland–McGill floor), ISOTYPE unit counts (Neurath), custom data glyphs (Lupi/Fragapane), and a lossless data table. Palette, glyphs, and composition are derived from the source's own content. No pies, donuts, gauges, 3D charts, or fabricated KPIs. Part of the reimagine-it Content-Derived Design suite.

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Clinical-trial readout analysis: pull the trial, evaluate the readout with AdCom-style scrutiny (endpoints, statistics, subgroups, missing data, safety, tolerability/persistence), place it in a cross-trial comparison lattice vs SoC and class peers, and size the stock reaction with historical grounding. The judgment core for binary biotech events.

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Weekly product-level commercial tracking — TRx/NRx with current/4-wk/12-wk share and YoY, launch curves overlaid with same-class analogs plus a consensus-implied trajectory, LOE/biosimilar erosion series, GTN/net-price stress brackets, and per-row data-caveat discipline. Use to track any launched drug, biologic, device, or vaccine against its class and consensus.

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Thesis report synthesis — turn a thesis's markdown artifacts into its letter-size thesis-report.html, then OPTIMIZE it against real page renders. Four-step loop — pack (deterministic Python bundle of all sources + report/metrics.json), author (the LLM writes report/content.html — narrative, KPI tiles, badges, timeline, tables and citations are LLM judgment), assemble (deterministic validation, template injection, Q50 pins, Q47 overflow gate), render + optimize (Chrome headless per-page PNGs — the LLM reads them and iterates until every page is visually clean). Spec 046 Q46–Q50.

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Quantitative stock screening, forward-looking valuation outlier detection, backward-looking financial statement validation, PEG ratio analysis, earnings growth profile assessment, turnaround vs value trap discrimination, data mining bias prevention

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Institutional-grade equity research skills for AI agents. 80 Claude-type skills across 14 verticals (equity-research-core, models-and-pitches, bio-pharm, scenarios, quantitative-analysis, idea-generation, options-derivatives, business-intelligence, industry-analysis, macro-strategy, portfolio-strategy, technical-analysis, risk-and-psychology, trading-as-business) powered by agentii.ai's agent-use-ready SEC filing data plane — SEC filings and 15K+ earnings call transcripts, 15.99M XBRL facts, and company profiles for 1,146+ US-public-equity tickers. Features the three-layer retrieval protocol (Document Discovery → Page Map → Deep Read, with deep-outline escalation) — measured, not asserted: 97.5% saved against a sequential read, and the page map itself is 10.0% of one (spec 062 T030, 2026-09-23) — server-side parallel multi-period search via search_cross_period, a full Excel/PPT generation pipeline with 3-tier office backend support, and the spec-046 governance layer (constitution, thesis and single-skill modes, mechanical gates, and a template-owned disclaimer on generated reports).

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This skill should be used when the user wants to query their Google NotebookLM notebooks for citation-backed, source-grounded answers, or manage notebooks, sources, and Studio content (audio, report, video, infographic, presentation, data table, flashcards, quiz, mind map). It drives the @roomi-fields/notebooklm-mcp engine — via the notebooklm MCP tools when they are available in the session, otherwise via its HTTP REST API — and covers Google login, citation formats, the daily-quota-aware batch/ingestion pattern, and source discovery.

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Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when changing file formats or preparing data for different tools.

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Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda window scheduling, soft-core potentials, REST2 enhanced sampling, MBAR/BAR analysis, and cycle closure validation. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.

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Build forest plots (HR, OR, RR, beta-coefficient summaries with CIs) and funnel plots (meta-analysis publication-bias diagnostics) using forestplot, metafor, ggforest, and MendelianRandomization with proper axis-scaling, summary-diamond placement, subgroup nesting, and Egger / trim-and-fill asymmetry tests. Use when summarizing effects across subgroups, trials, or instruments — meta-analysis, Mendelian randomization, subgroup HRs.

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Build Sankey, alluvial, river, and CONSORT-style flow diagrams to visualize cohort transitions, cell-state changes, or pipeline filtering using ggalluvial, networkD3, plotly, and consort. Use when showing how entities move between categories across timepoints (cell states, drug response classes, patient flow through a trial) or filtering pipelines (variants filtered through QC stages).

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Query the Ensembl REST API for gene/transcript/protein lookup, sequence retrieval, comparative genomics (Compara), variant effect prediction (VEP), regulatory features, and cross-species ortholog/paralog calls. Use when pulling Ensembl-native data (Ensembl Gene IDs, version-pinned releases, archive endpoints for reproducibility), gene/transcript/exon structure with stable IDs, or VEP for variant annotation. Encodes the 15 req/sec rate limit, archive (e110.rest.ensembl.org) for reproducibility, Ensembl divisions (vertebrates / plants / fungi / metazoa / bacteria), and the symbol-vs-ID stability problem.

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Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

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Read and manipulate Flow Cytometry Standard (FCS) files. Covers loading data, accessing parameters, and basic data exploration. Use when loading and inspecting flow or mass cytometry data before preprocessing.

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Detect and remove doublets from flow and mass cytometry data. Covers FSC/SSC gating and computational doublet detection methods. Use when filtering out cell aggregates before clustering or quantitative analysis.

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Plot per-group distributions of continuous data using boxplots, violins, beeswarms, quasirandom jitter, and raincloud plots with sample-size honesty (Weissgerber 2015), KDE-bandwidth awareness, and N-aware encoding choices. Use when comparing distributions across a small number of groups — expression per cluster, biomarker per arm, scores per condition — and the bar-of-mean default is misleading.

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Compute evolutionary distances and build phylogenetic trees using Biopython Bio.Phylo.TreeConstruction. Use when creating distance matrices from alignments, building NJ/UPGMA trees, generating bootstrap consensus, or needing quick exploratory phylogenies before running full ML analysis.

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Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.

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