开发技能

Read the user's local TradingView desktop app through opencli: quotes, options chains with greeks and per-strike IV, options expiries, screener results across stocks, crypto, forex, futures, and bonds, gainers and losers, news headlines and full stories, alerts (active, fired, offline fires), watchlists including colored flag lists, symbol search, chart state, and chart screenshots. Use this skill whenever the user asks for any of these from TradingView ("TV") — for example an options chain, puts, or IV skew for a ticker, an oversold-stock screen, their red flag list, which alerts fired, or a screenshot of their chart. For plain quotes, TA readouts, scans, or futures without the desktop app, prefer tradingview-mcp. Read-only: it never places trades or edits watchlists, alerts, or layouts.

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Query TradingView market data through the bundled tradingview MCP server without a desktop app or login. Use whenever the user wants a technical analysis readout (RSI, MACD, Bollinger rating, BUY/SELL summary), multi-timeframe alignment (weekly→daily→4h→1h→15m), exchange-wide scans (Bollinger squeeze, volume breakout, consecutive candles, smart volume), top gainers/losers by exchange, futures market data (NQ/ES/CL/GC overview, overnight movers, category snapshots), pre-market / after-hours quotes, a quick options chain or unusual options activity (volume/OI by strike), bulk stock prices, a global market snapshot, strategy backtests (Sharpe, drawdown, win rate), or crypto exchange scans. Triggers include "TA on X", "multi-timeframe read", "BB squeeze scan", "futures movers", "NQ overnight", "pre-market price", "unusual options activity", "backtest RSI on AAPL", and "top gainers on NASDAQ". For options greeks, watchlists, alerts, or chart screenshots use tradingview-reader instead.

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Builds the backend of an app clone: auth, database migrations and access rules, payments with Stripe, email, background jobs and third-party integrations through official APIs only, plus a security checklist. Use when the user says "add login", "set up auth", "wire up the database", "add payments", "connect Stripe", "add Google Calendar", "send emails", "backend for my clone", or when /replica-build is running on fake data.

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Manage AI coding agent sessions via Agent of Empires (aoe)

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Structured code review through the shared OpenClaw agent-skills installation.

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Explore and understand codebases using SocratiCode semantic search, dependency graphs, and context artifacts. Use when exploring code, understanding architecture, finding functions/types, analysing dependencies, searching database schemas or API specs, or when socraticode/codebase_search tools are available. Activates when the user asks about code structure, wants to find where a feature lives, or needs to understand how code is organised.

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Set up, index, and manage SocratiCode codebase indexing. Use when the user wants to index a project, check infrastructure health, start/stop file watching, configure context artifacts, troubleshoot indexing issues, manage the code graph, or any SocratiCode administrative task. Activates when the user mentions indexing, setting up search, SocratiCode infrastructure, or managing the codebase index.

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Push to GitHub and optionally bump version to trigger PyPI release

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Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-diseased tissue sites.

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Query the Ensembl database to resolve gene, transcript, and protein IDs, fetch genomic or protein sequences, retrieve gene structures (exons), and get variant consequence and effect predictions (VEP). Use this skill as a primary ID translator, genomic sequence database and variant effect prediction tool.

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Query the Genome Aggregation Database (gnomAD). Use when determining the rarity or allele frequency of specific genetic variants, retrieving gene constraint metrics (pLI, LOEUF) to assess loss-of-function intolerance, finding variants in a genomic region or gene, or querying structural variants. Don't use for analyzing individual patient genomes, tracking somatic mutations in cancer (use COSMIC), or requesting raw sequencing reads (use ENA).

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Query the JASPAR database for Transcription Factor (TF) binding profiles. Use when retrieving Position Frequency Matrices (PFMs) or Position Weight Matrices (PWMs) for specific TFs, resolving gene symbols to JASPAR Matrix IDs, or getting TF metadata. Supports multiple output formats (MEME, TRANSFAC, PFM, JASPAR, YAML).

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Score, annotate, and analyze the functional impact of genetic variants using AlphaGenome Variant Impact (AVI) scores. Query variants in chr:pos:ref>alt format, annotate VCF/tabular callsets, perform saturation mutagenesis window scans (1-based closed chr:start-end), and extract GENCODE v46 GTF gene/exon/junction coordinates all via the AlphaGenome Atlas API.

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Query the Reactome database (Analysis and Content Services). Use when the user asks about pathway analysis, gene list enrichment, retrieving results by token, finding unmapped or not-found identifiers, mapping identifiers, reaction participants (inputs, outputs), pathway hierarchy (including top-level pathways), diagram export, cross-reference mapping, or searching the knowledgebase.

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Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP), and transcription factors using the AlphaGenome API. Use when the user asks about non-coding variant effects, pathogenicity, clinical significance, disease associations, functional effects, gene expression changes, splicing disruption, or regulatory effects in promoters and enhancers. Also use for resolving biological terms to tissue/cell-type ontologies (UBERON/CL) or analyzing variants in chr:pos:ref>alt format.

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Use when you want to look up, map, and search for short genetic variants (SNPs, indels) in NCBI's dbSNP database. Resolves between rsIDs, genomic coordinates in VCF format, and HGVS strings. For an rsID, returns variant type, gene associations, clinical significance, allele frequencies, and genomic coordinates (GRCh38).

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Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate file (.cif, .mmcif, or .pdb) and wants to find structurally similar proteins. Do NOT use if the user only provides a protein sequence, gene name, or UniProt ID.

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Retrieve and analyze AlphaFold predicted structures for a protein. Use when the user provides a specific UniProt Accession ID and wants structural confidence metrics (pLDDT), domain boundary analysis, or disorder assessment. Do not use if the user only has a protein name, gene name, or amino acid sequence — ask for a UniProt ID first.

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Query the QuickGO and Evidence & Conclusion Ontology (ECO) REST API. Use this when you need to map genes to biological processes, molecular functions, or cellular components, find genes associated with a specific pathway/GO term, or explore the Gene Ontology hierarchy. Do not use for querying drug targets (use OpenTargets) or mechanistic signaling pathway diagrams (use KEGG).

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Query, search, and download data from the openFDA API for drugs, devices, foods, tobacco, cosmetics, animal and veterinary products, substances, and transparency data. Use for FDA adverse events, recalls, labeling, approvals, shortages, 510(k) clearances, NDC lookups, and any FDA safety or regulatory data query across all 28 API endpoints.

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Query the ChEMBL database for bioactive molecules, drug targets, bioactivity data, approved drugs, and chemical structures. Use when the user asks about compounds, targets, IC50/Ki values, drug mechanisms, or structure searches.

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Checks whether the uv Python package manager is installed and installs it if missing. Ensures uv is on PATH. Use when another skill requires uv as a prerequisite.

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Use when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA).

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Retrieve protein and nucleotide sequences from NCBI databases using E-utilities. Supports direct accession lookup, CDS translation, gene+organism search, locus lookup, PubMed-linked sequences, patent protein extraction, and organism+length fallback search. Use when you need to fetch biological sequences by accession, gene name, locus tag, PubMed ID, or patent number.

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