邮件、日历、任务管理、自动化（7824 个）
Use when preparing FBT year-end work for an Australian employer: identifying fringe benefits, collecting declarations, applying gross-up, calculating reportable fringe benefits amounts, and building the FBT return workpaper. FBT year runs 1 April to 31 March.
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Ingest documents, articles, conversations, or supplied text into Knowledge with retained originals, sourced claims, entity updates, timelines, and cross-links. Routes meetings to knowledge-meeting-ingest and short thoughts to knowledge-capture.
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Ingest meeting transcripts from any recorder into Knowledge with attendee enrichment, timeline merge, supported decisions and commitments, and verification of substance and sequence. Summary-only input is not a verified meeting ingestion.
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Create scheduled Knowledge ingestion automations with a verified worker, private-vault authority, and an end-to-end scheduled run. Use when asked to schedule or repair recurring ingestion from any source.
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Instabox を使う検証用の開発タスクに対し、ローカル司令・クラウド内の開発継続・外部での仕事と復旧の管理を比較して仮選定し、小さな実装・検証実験で適否を判断する。開発構成の試行や切断・復旧の検証に使う。基本接続だけなら instabox を使う。
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Guide for creating effective skills. This skill should be used when users want to create a new skill (or update an existing skill) that extends Claude's capabilities with specialized knowledge, workflows, or tool integrations.
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Draft and quality-check pages for the IPA Knowledge Hub in the site's house style. Use when creating a new .qmd Hub page from source material, adapting outside content into a Hub page, or reviewing an existing page for structure, tone, frontmatter, references, and Diátaxis fit. Replicates the quality-control workflow of IPA's Knowledge Hub Generator assistant.
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Operate desktop apps and isolated browsers on registered computers. Use for tasks that require an app interface, accessibility, screenshots or recording. Use Chromewhale for the user's signed-in Chrome.
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Design durable workflows with Temporal for distributed systems. Covers workflow vs activity separation, saga patterns, state management, and determinism constraints. Use when building long-running processes, distributed transactions, or microservice orchestration.
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Maps incoming work to the CodeConductor slash command and workflow skill. Use when starting a session or deciding which /cc-* command applies.
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Guides agents through scorecards, outcomes, model profiles, and eval suites. Use when running /cc-scorecard or /cc:scorecard, measuring a deliverable, or checking workflow gates with suite-run.
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Set up something that runs on a schedule (a weekly report, a daily digest) as a scheduled workflow, change, pause or debug one, and build interactive pages (project artifacts and workspaces) that read live Fabric data. Use when the user asks for a recurring job, a status page, a dashboard or a page with buttons, or asks why one did not run.
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Claude Code のセッション記録（~/.claude の履歴・セッションログ・memory）から、週ごとの問い（questions.json）に答える「ナレッジカード」を下書きし、本人が確認・修正したうえで機密スキャンを通し、Notion の「ナレッジカード」DB に提出する。引数なしなら先週（月曜〜日曜）の記録を集計し、確認のうえ Notion に提出する。「Claude Code の履歴をナレッジカードにまとめて」「先週のログからナレッジカードを作って」「ナレッジカードを提出したい」「今週のカードを出して」「週次の振り返りカードを作って」などの依頼で使う。週次のカード提出であり、個人の採点や評価ではない（セッション 1 本の採点は evaluate-session の領域）。
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週ごとに Notion「ナレッジカード」DB に集まったカードを読み、問いをまたいで親和図にまとめ、正（worked）と反（failed）の対立から合（提案）を出し、次の問いを決めて、「合成テーマ」DB と週の行の配下の「まとめ」ページに書き込む。「今週のカードを合成して」「W43 のまとめを作って」「ナレッジカードの合成」などの依頼で使う。カードの提出は knowledge-cards、個人の採点は evaluate-session の領域。個人別の件数ランキングや「誰が何を失敗した」は出さない。
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Detects and removes contamination in genome assemblies via two disjoint workflows - foreign-sequence screening of a single-organism (eukaryote/isolate) assembly with NCBI FCS-GX (GenBank-submission-mandatory), FCS-adaptor, and BlobToolKit blob plots; and MAG/bin quality assessment with CheckM2 plus GUNC (chimerism) plus GTDB-Tk taxonomy, judged against MIMAG. Covers why CheckM2 alone is blind to disjoint-marker chimeras, the FCS-GX RAM wall, organelle/NUMT triage, strain heterogeneity, and the HGT-vs-contamination (tardigrade) trap. Use when screening an assembly for foreign contamination before GenBank submission, assessing MAG completeness/contamination/chimerism, deciding which contigs to remove, or distinguishing real HGT from contaminant contigs.
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Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq c_curve / lc_extrap, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT — see Tips), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for downstream cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for downstream visualisation.
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Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF-to-FDR calibration (BF >6 ≈ FDR 0.05 from Hart 2017). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.
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Call copy number variants with the GATK best-practices workflows — the somatic CNV pipeline (CollectReadCounts, DenoiseReadCounts with tangent normalization, ModelSegments, CallCopyRatioSegments) and the germline GATK-gCNV pipeline (DetermineGermlineContigPloidy, GermlineCNVCaller cohort/case mode, PostprocessGermlineCNVCalls). Covers panel-of-normals construction, AnnotateIntervals/FilterIntervals, allelic-count integration, and QS-based filtering. Use when integrating CNV calling into a GATK variant pipeline, calling rare germline CNVs from an exome cohort, deciding between the somatic and germline GATK workflows, or diagnosing why tangent normalization removed a real event or why gCNV output has low precision.
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Performs structure-based virtual screening using AutoDock Vina, SMINA, GNINA (CNN scoring), and DiffDock-L hybrid workflows with explicit choice rules across rigid vs flexible docking, cross-docking vs self-docking, binding-site detection (P2Rank, fpocket), receptor preparation (PDB2PQR, PROPKA), ligand preparation (meeko, OpenBabel), and ultralarge-library screening (ZINC22, Enamine REAL). Use when screening chemical libraries against a protein target to find candidate binders, ranking docking poses, or selecting a docking workflow for a specific scenario.
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Builds and applies 3D pharmacophore models using RDKit Pharm3D, the apo2ph4 receptor-based workflow (Heider et al 2022/2023 J Chem Inf Model 63:147-158), Pharmer / Pharmit (search), and PharmacoForge (diffusion-based generation, Flynn et al 2025 Front Bioinform), covering ligand-based pharmacophore (from active set alignment) and receptor-based pharmacophore (from binding pocket geometry). Explicit handling of feature types, geometric tolerances, partial matching, and pharmacophore-based virtual screening. Use when identifying scaffold-hopping candidates, building shape-and-feature search queries, or transferring SAR across chemotypes.
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Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories. Use when setting up bioinformatics capabilities or when a bioinformatics task requires specialized skills not yet installed.
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Run OpenSpec backlog delivery — validate BACKLOG.md, plan TaskCards, orchestrate agents by phase, review gate, and update backlog state.
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Re-explain the last deliverable in Task Card vocabulary when it did not land.
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Council-driven workflow with CCEP-1 bootstrap
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