调研、论文、教育、考证学习（4209 个）
Search the 1000 Genomes Project’s 3,202 participants for genetic variants and their carriers. Filter by frequency or annotations, inspect variants in selected individuals, and check relatedness between two participants.
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Prepare and run molecular dynamics simulations with OpenMM, then analyze molecular motion with MDAnalysis. Examine protein flexibility, structural changes, and protein–ligand contacts through calculations and plots of simulated trajectories.
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Prepare experiments for Ginkgo Cloud Lab by choosing a protocol, organizing required inputs, checking configured pricing, and navigating browser ordering. Covers protein expression, RNA synthesis, stability assays, and setup of measurement methods.
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Create, review, migrate, and simulate Python liquid-handling protocols for Opentrons Flex and OT-2 robots. Covers deck layout, labware, pipettes, modules, volumes, and tip policies, with checks for Opentrons App analysis and operator review before physical runs.
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Plan and review fluid simulations with FluidSim, from solver selection and resource estimates to output analysis and restart checks. Examine numerical accuracy through grid and time-step comparisons, conservation checks, and explicit limits on computing resources.
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Plan protein characterization experiments with Adaptyv's cloud laboratory, estimate costs, submit sequences, track progress, and retrieve measured results. Supports binding, thermal stability, expression, fluorescence, and enzyme activity workflows through the API and Python SDK.
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Use COBRApy to model metabolic networks and calculate possible reaction flows under defined constraints. Compare gene knockouts, nutrient conditions, and production limits, while checking model validity and keeping computational predictions separate from experimental findings.
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Search scientific papers by topic or DOI, a paper’s identifier, and organize evidence extracted from full text. Connect claims with experiments, reported statistics, limitations, and source locations for literature reviews and evidence tables.
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Generate candidate positions and orientations for small molecules binding to proteins with DiffDock and DiffDock-L. Prepare single or batch docking runs, organize predicted poses by model confidence, and review validation needs without treating confidence as binding affinity.
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Analyze existing evolutionary trees and other hierarchical trees with ETE 4. Edit branches, add annotations, compare branching structures, explore large trees interactively, and render figures for publication using the appropriate optional visualization components.
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Simulate a uniform gas mixture in a closed, insulated reactor at constant volume or pressure. Calculate ignition delay from the peak temperature rise rate, export temperature and species histories, and check conservation and numerical stability.
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Search scientific and technical topics with Exa, prioritize scholarly sources using publication and domain filters, and extract text from webpages or PDFs in batches to collect material for research.
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Retrieve facts from named scientific, regulatory, economic, and other databases through documented APIs. Get results with recorded filters, retrieval dates, and record counts so another person can repeat the lookup and assess its completeness.
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Investigate how DNA variants may affect gene activity using precomputed AlphaGenome Atlas results and model predictions. Rank candidate variants, examine tissue-specific effects, and inspect the features behind scores to develop research hypotheses about biological mechanisms.
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Find academic papers, verify authors and publication details, and create BibTeX entries, a structured format for references. Use it to organize bibliographies, remove duplicates, and check missing fields or mismatches with a manuscript.
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Organize MRI, EEG, and other biomedical research data using BIDS, a shared standard for filenames, folders, and metadata. Query datasets, check compliance, convert DICOM files, and prepare metadata or processed outputs for analysis and sharing.
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Process next-generation sequencing data with deepTools: convert alignment files into coverage tracks, normalize signals, compare samples, and check quality. Create heatmaps and profiles around genes or peak regions for ChIP-seq, RNA-seq, and ATAC-seq experiments.
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Plan experiments before collecting data. Helps choose study designs, randomly assign subjects or samples, organize treatment combinations, and generate reproducible schedules while checking for confounding and repeated measurements incorrectly counted as independent samples.
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Retrieve public evidence and linked publications for a supported genetic variant, or look up gene–disease relationships. Preserve sources, conflicting assertions, and explicit search outcomes so qualified professionals can review the findings.
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Prepare and check research documents for clinical decision-support evaluation, including evidence profiles, cohort tables, survival plans, and model assessments. Work with aggregate or synthetic inputs, record sources and review status, and keep outputs outside patient care.
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Automate lab data tasks in Benchling using its Python SDK and REST API. Import and export sequences, inspect sample inventory, and work with electronic lab notebooks and workflow tasks while checking schemas, permissions, and operation results.
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Develop a social science research direction from an initial interest, organize the literature, and assess evidence and feasibility. Structured worksheets help compare research questions, challenge novelty claims, and keep academic wording within what the evidence supports.
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Read a supplied paper in depth and produce a structured Markdown explanation of its research logic, essential design choices, and evidence limits. Work through key equations with concrete numerical examples and identify missing controls or unreported information.
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Draft or review manuscript statements explaining where data and code can be accessed. Organize repository choices, access restrictions, identifiers, and dataset citations, and check metadata that helps others find and reuse the research data.
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