Applies the foundationalist reasoning and methodological doubt of René Descartes (17th-century French rationalist philosopher). Use this skill whenever the user is questioning fundamental assumptions, seeking absolute certainty in a decision, dismantling flawed systems, or trying to rebuild a project from first principles. Trigger this skill for topics involving epistemology, rationalism, radical doubt, systemic reconstruction, or separating objective truth from sensory illusion. Reach for this whenever a user needs to cut through probabilities and consensus to find an indubitable 'Archimedean point' to build upon.
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Applies the reasoning, AI safety frameworks, and deep learning principles of Yoshua Bengio (Turing Award winner, Mila). Reach for this skill whenever you are discussing AI safety, existential risk, deep learning architecture, representation learning, or AI governance. Trigger this skill when the user asks about mitigating AI risks, designing safe-by-design systems, evaluating frontier models, international AI coordination, or the fundamental mechanisms of intelligence (like compositionality and distributed representations). Use it to shift the focus from agentic reward-maximization to non-agentic 'Scientist AI', apply the precautionary principle to catastrophic risks, and emphasize mathematically rigorous guardrails.
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This skill channels the strategic and empathetic reasoning of Whitney Wolfe Herd, founder and CEO of Bumble. Use this skill whenever you are advising on platform safety, double-sided marketplace dynamics, women's empowerment, purpose-driven entrepreneurship, or overcoming professional trauma. It is highly applicable when users face decisions about product constraints (like time limits or behavioral guardrails), balancing digital engagement with real-world connection, or navigating outdated social dynamics. Reach for this skill to help users shift from 'me to we,' engineer kindness into their products, and focus on core inputs rather than vanity metrics.
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Applies the reasoning, mental models, and capital allocation frameworks of Warren Buffett, CEO of Berkshire Hathaway and value investor. Use this skill whenever the user is evaluating investments, making capital allocation decisions, structuring management and governance, assessing business economics (moats, intrinsic value), navigating market volatility, or making long-term career and partnership choices. Trigger this skill for topics involving value investing, corporate finance, decentralization, and long-term strategic thinking, even if the user doesn't explicitly name Buffett.
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This skill channels the reasoning of Walter C. Willett, nutrition epidemiologist at Harvard University. Use this skill whenever you are asked to evaluate diets, give nutritional advice, critique food policy, or discuss the environmental impact of food systems. Trigger this skill for topics like macronutrient quality (fats vs. carbs), plant-based diets, the health impacts of red meat or dairy, seed oils, epidemiological methodology, and planetary health. Apply his frameworks to shift focus from macronutrient quantity to quality, evaluate foods using the 'Compared to what?' rule, and prioritize public health over personalized nutrition fads.
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Applies the reasoning of Mary Wollstonecraft (18th-century English philosopher and author of A Vindication of the Rights of Woman) to evaluate situations involving power dynamics, education, independence, gender roles, and systemic inequality. Use this skill whenever Claude encounters career trade-offs involving financial dependence, analyzing structural oppression, questioning societal norms, or balancing reason against emotion. It helps dismantle arbitrary hierarchies, prioritize rational capability over superficial elegance, and frame personal struggles as political realities.
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Applies the philosophical frameworks of Plato (ancient Greek philosopher, Theory of Forms, founder of the Academy) to structural, ethical, and epistemological problems. Use this skill whenever the user is grappling with organizational design, leadership ethics, defining abstract concepts, aligning incentives, or uncovering the root essence of a problem. Trigger this when discussing justice, governance, the nature of knowledge, structural harmony, or when a user is trapped by superficial metrics (shadows) and needs to find fundamental truths (Forms). Do not wait for the user to name Plato; proactively apply his dialectical reasoning to cut through illusions.
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This skill channels the strategic thinking of Walt Disney, co-founder of The Walt Disney Company and animation pioneer. Use this skill whenever you are advising users on creative control, intellectual property, brand building, storytelling, or balancing quality with profit. It is highly effective for situations involving product diversification, media synergy, adapting classic works for mainstream audiences, or designing ambitious, future-proof prototypes (like urban planning or platform ecosystems). Trigger this skill when users face pressure to repeat past successes (sequels), deal with middlemen, or need to elevate a team's creative output through constructive feedback.
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Apply this skill whenever evaluating neurodegenerative disease research, protein misfolding, experimental rigor, or career longevity for women in STEM. Use this to channel the thinking of Virginia M.-Y. Lee, neuroscientist at the University of Pennsylvania known for her pioneering work on neurodegeneration. Trigger this skill when discussing Alzheimer's, Parkinson's, ALS, protein aggregation, cell-to-cell transmission of pathology, brain banking, or multidisciplinary scientific collaboration. It is highly relevant when users need critiques on biological models, advice on sustaining a long scientific career, or frameworks for translating clinical pathology into basic science.
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Applies the developmental psychopathology and longitudinal research frameworks of Terrie E. Moffitt (psychologist, Duke University). Use this skill whenever reasoning about human development, criminology, juvenile delinquency, self-control, mental health trajectories, or biological aging. Trigger this when asked to evaluate the origins of antisocial behavior, the impact of childhood traits on adult outcomes, the validity of psychiatric diagnoses (comorbidity), or anti-aging interventions. Apply her models to shift focus from cross-sectional snapshots to longitudinal life-course trajectories, emphasizing the 'p' factor, the self-control gradient, and the dual taxonomy of antisocial behavior.
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Applies the epidemiological and aging research frameworks of Tamara B. Harris (epidemiologist, National Institutes of Health). Use this skill whenever analyzing health metrics in older populations, designing longitudinal studies, evaluating body composition (muscle quality vs. mass), assessing dementia risk factors, or interpreting paradoxical risk factors in geriatrics. Trigger this skill when the user asks about aging, longevity, functional decline, socioeconomic health disparities, or when evaluating clinical trial data where reverse causation or subgroup stratification might skew results.
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Applies the reasoning of Stuart Russell, AI safety expert, UC Berkeley professor, and co-author of 'Artificial Intelligence: A Modern Approach'. Reach for this skill whenever evaluating AI safety, value alignment, the control problem, existential risk, AI regulation, or autonomous weapons. Use this when the user is discussing objective uncertainty, reinforcement learning risks, AI governance, or the societal impacts of AGI. Trigger this skill to apply his frameworks on provably beneficial AI, assistance games, and red-line regulation, ensuring AI systems remain deferential, uncertain of their objectives, and strictly aligned with human preferences.
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Applies the product philosophy and leadership frameworks of Steve Jobs, co-founder and CEO of Apple Inc. Reach for this skill whenever the user is navigating product design, customer experience, innovation, hiring top-tier talent, or defining corporate culture. Trigger this skill for questions about finding product-market fit, making career trade-offs, building hardware/software ecosystems, or establishing brand values. Use this to push back against feature creep, committee-driven decisions, and technology-first thinking. Apply Jobs's mental models to help users simplify complex systems, focus on craftsmanship, and build products that sit at the intersection of technology and the liberal arts.
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Apply this skill whenever the user is navigating early-stage startups, bootstrapping, product innovation, branding, or overcoming the fear of failure. Sara Blakely, founder of Spanx and self-made billionaire, approaches business by leveraging 'the outsider advantage,' relying on intuition, and obsessing over consumer empathy. Trigger this skill for discussions about funding trade-offs (bootstrapping vs. VC), naming products, dealing with imposter syndrome, entering an industry with zero experience, or building an authentic, vulnerability-driven company culture. Reach for her mental models when users are tempted to share fragile ideas too early, fear embarrassment, or need to rethink how they approach product-market fit.
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Applies the operational and scientific frameworks of Stacey Gabriel (genomicist and sequencing platform leader at the Broad Institute). Use this skill whenever the user is designing large-scale biomedical research, operationalizing lab workflows, standardizing data governance, or transitioning from bespoke academic experiments to industrial-scale science. It is highly relevant for queries involving genomics, precision medicine, multiomics, cellular perturbation pipelines, or building massive datasets to fuel AI. Trigger this skill to shift the user's focus from 'hand-to-hand combat' one-off studies to systematic, standardized, and scalable data generation.
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Applies the dialectical reasoning and intellectual humility of Socrates (ancient Greek philosopher, 470-399 BCE). Use this skill whenever the user is grappling with fundamental definitions, moral dilemmas, educational approaches, self-reflection, or making high-stakes ethical decisions. Trigger this skill when encountering topics like virtue, justice, the pursuit of truth, questioning assumptions, coaching, or when the user seems overly confident in unexamined beliefs. It helps dismantle false assumptions through probing questions and redirects focus toward the "care of the soul" and objective truth over external validation or material success.
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This skill applies the analytical frameworks of Ronald C. Kessler, psychiatric epidemiologist at Harvard University, to problems in precision psychiatry, clinical trial design, and healthcare machine learning. Use this skill whenever you are designing clinical trials, evaluating mental health interventions, analyzing epidemiological survey data, or building clinical decision support algorithms. It is highly relevant when the user asks about sample sizes, treatment matching, patient attrition, suicide prevention, or predictive modeling in healthcare. Trigger this skill to prioritize massive observational data, tiered predictive models, and human-in-the-loop AI over underpowered randomized trials and expensive, unscalable biomarkers.
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Applies the existentialist and feminist philosophy of Simone de Beauvoir, French philosopher and author of The Second Sex. Reach for this skill whenever the user is grappling with existential dilemmas, moral ambiguity, gender dynamics, societal expectations, or relationship ethics. Trigger this skill for questions about freedom versus responsibility, bodily autonomy, marginalization, or when the user feels trapped by external labels or "immanence." Use this to help the user reclaim their agency, recognize the social construction of their situation, and make authentic choices that expand their transcendence while respecting the interconnected freedom of others.
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Use this skill when reasoning about deep tech commercialization, biomedical engineering, drug delivery, material design, or overcoming institutional skepticism. Robert Langer, MIT professor and pioneer of drug delivery systems, approaches problems through first-principles engineering, interdisciplinary convergence, and relentless perseverance against consensus. Trigger this skill whenever the user is evaluating high-risk/high-reward research, deciding between incremental vs. paradigm-shifting impact, spinning out academic discoveries into startups, or designing physical/biological systems from scratch. Apply his frameworks to navigate patenting, funding, and translating lab science into real-world impact.
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Applies the reasoning, frameworks, and mental models of Fei-Fei Li, computer vision pioneer, ImageNet creator, and co-director of Stanford HAI. Use this skill whenever Claude encounters topics related to AI ethics, human-centered AI, spatial intelligence, embodied AI, robotics, AI governance, diversity in tech, or the societal impacts of AI. Trigger this skill when users face decisions about AI product design (augment vs. replace), dataset formulation, navigating AI regulation, or choosing audacious research directions. Channel her pragmatic optimism and focus on spatial, physical grounding over pure language models.
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Applies the behavioral genetics and twin-study methodologies of Dorret I. Boomsma (behavior geneticist, Vrije Universiteit Amsterdam). Use this skill when reasoning about heritability, genetic epidemiology, nature vs. nurture debates, psychiatric genetics, or longitudinal phenotyping. Trigger this whenever the user asks about the genetic basis of intelligence, lifestyle factors, educational attainment, or psychopathology, or when designing epidemiological studies. It helps deconfound environmental and genetic variables using extended family designs and discordant twin models.
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Reach for this skill whenever Claude encounters situations involving supply chain innovation, B2B customer respect, community revitalization, vocational education, or navigating massive business crises. Apply the mental models of Diane Hendricks, co-founder of ABC Supply and building supplies billionaire, when users face decisions about strategic acquisitions, counter-cyclical expansion, or treating blue-collar workers as respected entrepreneurs. Use this skill to channel her 'fight or fold' resilience, her strict financial responsibility hierarchy, and her focus on solving the exact pain points you faced as a customer.
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This skill channels the strategic and scientific reasoning of Demis Hassabis, CEO and co-founder of Google DeepMind, AlphaGo and AlphaFold, and 2024 Nobel Prize in Chemistry. Use this skill whenever you are evaluating AI for scientific discovery, tackling "root node" problems, designing reinforcement learning systems, or discussing AGI timelines, safety, and global governance. Reach for it when the user faces massive combinatorial search spaces, wants to apply AI to physical/biological sciences (like digital biology), or needs to balance rapid AI scaling with the rigorous scientific method. Apply these mental models to shift the focus from building consumer apps to using AI as the ultimate meta-solution for understanding reality.
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Applies the reasoning of David Silver, lead researcher on AlphaGo and AlphaZero at DeepMind, to problems of AI design, reinforcement learning, and open-ended discovery. Use this skill whenever you are designing AI systems, evaluating learning algorithms, balancing exploration vs. exploitation, choosing research problems, or discussing how to break past human performance ceilings. Reach for this whenever the user asks about self-play, Monte-Carlo Tree Search, tabula rasa learning, AGI, or moving from human-curated data to autonomous experience. It helps shift the focus from hardcoding human knowledge to building systems that learn for themselves.
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