Anthropic

Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and visualization. When Claude needs to work with spreadsheets (.xlsx, .xlsm, .csv, .tsv, etc) for: (1) Creating new spreadsheets with formulas and formatting, (2) Reading or analyzing data, (3) Modify existing spreadsheets while preserving formulas, (4) Data analysis and visualization in spreadsheets, or (5) Recalculating formulas

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The SRE team's runbook for triaging production latency and error-rate incidents. Use this whenever investigating an incident, a latency spike, elevated error rates, or when asked "what caused X" about a production service.

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How the SRE team writes a postmortem PDF. Use this whenever asked for a postmortem, an incident report, a write-up to share, or a PDF of what happened.

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Fixed-format templates for Slack alerts, supplier emails, and escalations. Load this whenever the task is "notify", "alert", "email", or "tell ops".

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How to rank and pick a supplier for a SKU. Load this whenever a task involves choosing a supplier, comparing quotes, or creating a purchase order.

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How to decide whether and how much to reorder a SKU. Load this whenever a task involves reorder recommendations, purchase orders, or "should we restock" questions.

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Structure and data sources for the weekly inventory report. Load this when the task is "weekly report", "Monday report", or "summarize inventory status".

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Workshop coach for the Research Desk (SEC agents) workshop. Use when the user types /workshop, asks for a workshop act or module ("act 2", "next act", "where am I"), wants a TODO(workshop-N) implemented or explained, or asks for help following WORKSHOP.md.

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Guide a workshop attendee through committing their starter-agent decomposition and opening a PR with their solution + workshop feedback. Invoke when the user says "submit", "I'm done", "open a PR", or asks how to share their solution.

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How to produce a demand forecast for a SKU, and when to delegate that to a subagent vs. compute it yourself. Load this for any task involving "forecast", "how much will we sell", "next month", promos, or seasonal SKUs.

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How to pull SEC EDGAR data with the edgartools Python package — company lookup, filings, XBRL financial statements, and filing sections like Item 1A risk factors. Use whenever a task involves SEC filings, 10-K/10-Q data, or company financials.

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Where diamonds spawn in Minecraft 1.20.

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Close out (or revisit) a Claude Managed Agent build — refresh the overview page, recap every primitive the founder now owns, show the run log and live status, suggest 1–2 tailored next upgrades, and sweep hygiene (sessions archived, key only in .env, no literal dates in deployment kickoffs). Use when the founder says "/wrap-up", "wrap up", "close it out", "where do things stand with my agent", or at the end of a /launch-your-agent build.

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Help a technical founder build whatever they want on Claude Managed Agents — an internal worker, a piece of their product, a customer-facing agent. Find out what they want to build, scope a v0, launch it in their account, grade it, iterate, and (if it should run on a clock) put it on a scheduled deployment, with everything bigger laid out as v1/v2. Use when a founder says "launch my agent", "/launch-your-agent", "build me a managed agent", or wants to build something on CMA. Keywords: managed agents, CMA, founder, launch, scheduled deployment, outcome rubric.

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Run a large-scale language migration with the six-step process: create the map and the rules, stress-test the rules, translate everything, compile, run it, match behavior. Use when the user wants to migrate, port, or rewrite a codebase from one language to another ("migrate this to Rust", "port our Python CLI to TypeScript", "should we rewrite this in Go?"), or asks for a migration feasibility assessment. Not for incremental JS→TS adoption — that needs no machinery — or single-file conversions.

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Generate clinical trial protocols for medical devices or drugs. This skill should be used when users say "Create a clinical trial protocol", "Generate protocol for [device/drug]", "Help me design a clinical study", "Research similar trials for [intervention]", or when developing FDA submission documentation for investigational products.

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Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV. Use this skill when scientists need to standardize instrument data for LIMS systems, data lakes, or downstream analysis. Supports auto-detection of instrument types. Outputs include full ASM JSON, flattened CSV for easy import, and exportable Python code for data engineers. Common triggers include converting instrument files, standardizing lab data, preparing data for upload to LIMS/ELN systems, or generating parser code for production pipelines.

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Performs quality control on single-cell RNA-seq data (.h5ad or .h5 files) using scverse best practices with MAD-based filtering and comprehensive visualizations. Use when users request QC analysis, filtering low-quality cells, assessing data quality, or following scverse/scanpy best practices for single-cell analysis.

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Deep learning for single-cell analysis using scvi-tools. This skill should be used when users need (1) data integration and batch correction with scVI/scANVI, (2) ATAC-seq analysis with PeakVI, (3) CITE-seq multi-modal analysis with totalVI, (4) multiome RNA+ATAC analysis with MultiVI, (5) spatial transcriptomics deconvolution with DestVI, (6) label transfer and reference mapping with scANVI/scArches, (7) RNA velocity with veloVI, or (8) any deep learning-based single-cell method. Triggers include mentions of scVI, scANVI, totalVI, PeakVI, MultiVI, DestVI, veloVI, sysVI, scArches, variational autoencoder, VAE, batch correction, data integration, multi-modal, CITE-seq, multiome, reference mapping, latent space.

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This skill should be used when scientists need help with research problem selection, project ideation, troubleshooting stuck projects, or strategic scientific decisions. Use this skill when users ask to pitch a new research idea, work through a project problem, evaluate project risks, plan research strategy, navigate decision trees, or get help choosing what scientific problem to work on. Typical requests include "I have an idea for a project", "I'm stuck on my research", "help me evaluate this project", "what should I work on", or "I need strategic advice about my research".

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Run nf-core bioinformatics pipelines (rnaseq, sarek, atacseq) on sequencing data. Use when analyzing RNA-seq, WGS/WES, or ATAC-seq data—either local FASTQs or public datasets from GEO/SRA. Triggers on nf-core, Nextflow, FASTQ analysis, variant calling, gene expression, differential expression, GEO reanalysis, GSE/GSM/SRR accessions, or samplesheet creation.

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Adapts an existing K-12 lesson (math, ELA, science, or social studies) for students at different proficiency levels (below / at / above grade level). Load this skill BEFORE asking the teacher any clarifying question about the lesson, tiers, or student levels. Triggers on explicit asks to differentiate, tier, or scaffold a lesson, and on implicit signals like "my students are at different levels". Produces 1 teacher-facing differentiation plan + 3 student-ready tier documents as editable, printable documents in a single output turn (shared content is written once, so tiers cannot drift). Uses the Learning Commons Knowledge Graph when connected; works without it. This skill adapts a lesson the teacher brings or names. Not for creating a new lesson from scratch — a new-lesson request that asks for differentiated or leveled materials is k12-lesson-plan-creation's job, one package. Not for grading, rubrics, assessment feedback, or quizzes.

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Helps a teacher prepare to teach an existing K-12 lesson (math / ELA / science / social studies) — a prep partner that thinks through the lesson's key student task with the teacher and leaves a short teacher-only prep note. Triggers on asks to internalize, prepare for, get ready to teach, or understand a lesson, including implicit ones ("help me get ready for tomorrow's lesson"), and right after another skill built a lesson, which it can follow. Not for building or adapting a lesson, grading, rubrics, assessment feedback, or generating quizzes or student-facing material, and not for single-fact lookups a sentence would answer ("what standard is this?", "how long is this lesson?").

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Creates a lesson plan, student-facing materials, and observation template. Load this skill BEFORE asking the teacher any clarifying question about grade, subject, topic, standard, or timing. Use when a K-12 teacher needs a math, ELA, science, or social studies lesson built from scratch — even if grade, subject, or topic isn't yet stated. Do NOT load for grading, a rubric, assessment feedback, a quiz, or a standards lookup — answer those directly. Triggers on explicit requests (lesson plan, mini-lesson, unit plan, daily plan) and implicit teacher intent: "I'm teaching long division to 5th graders," "need to teach photosynthesis tomorrow." Core signal: teacher needs new instructional content created. A new lesson that asks for differentiated, tiered, or leveled materials is still ONE planning request — this skill produces those materials inside the lesson package; do not also invoke k12-lesson-differentiation. Not for differentiating an existing lesson (use k12-lesson-differentiation) or passage rewrites.

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