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DNA methylation analysis — array and bisulfite-seq processing, DMP/DMR calling, and epigenetic clocks.

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Manage software composition analysis — SBOMs, vulnerability triage, and remediation of third-party dependencies.

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.NET guidance — ASP.NET Core APIs, Entity Framework Core, DI, configuration, testing, and container deployment.

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Build rich visualizations with Apache ECharts: option config, dataset transforms, large-data performance, and custom rendering. Use for complex dashboards and big datasets.

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Dose-response modeling — EC50 estimation, curve fitting, synergy analysis, and benchmark-dose methods.

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Electronic lab notebook workflows — structuring entries, templates, linking data, and audit-ready records.

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ELISA development and validation — sandwich vs competitive formats, standard curves, and assay qualification.

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Apply the devil's advocate technique: structured critical thinking that stress-tests ideas, plans, and decisions. Use when you need honest critique before committing to something important.

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Idiomatic Elixir: functional design, OTP supervision, GenServers, Ecto, and Phoenix patterns. Use when writing, reviewing, or structuring Elixir applications.

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Review Dependabot PRs efficiently: triage, risk assessment, batching, and auto-merge policies. Use when dependency update PRs pile up or you want a sane update workflow.

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Reusable deployment templates — one-click deploys, blueprints, and environment-as-code — vendor-neutral patterns.

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Elasticsearch guidance — index design, mappings, query DSL, aggregations, cluster operations, and performance tuning.

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Build and govern scalable design systems with tokens, components, documentation, and adoption strategy.

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Structured differential diagnosis — generating, prioritizing, and ruling out diagnostic hypotheses.

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Embed security into DevOps — pipeline security gates, guardrails, and culture that ships fast and safe.

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Elasticsearch search and analytics — mappings, queries, and cluster health — use when building search or log analytics.

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Generate and edit images with diffusion models: prompting, seeds, CFG, img2img, inpainting, conditioning, and API integration. Use when adding AI image generation to apps or workflows.

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Affordable serverless GPU inference on DeepInfra — broad open-model catalog with straightforward pricing.

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Build with DeepSeek's models — efficient open-weight reasoning models and low-cost API inference.

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Deploy and operate endpoint detection and response — policy tuning, behavioral detections, threat hunting, and response actions.

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Build with DeepSeek Coder — open code models with strong reasoning and long-context code understanding.

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Apply classic design patterns judiciously: when each pattern fits, modern alternatives, and anti-patterns. Use when designing object interactions or reviewing pattern usage.

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EEG preprocessing and analysis — filtering, artifact removal, time-frequency decomposition, and ERP workflows.

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Deno runtime guidance — TypeScript-first development, permissions, standard library, and deploying Deno apps.

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