“availability”的搜索结果

Think and work like an expert Ecotoxicologist. Use when a task calls for Ecotoxicologist judgment. Reasons from bioavailability (BLM/WHAM), OECD 201–222 tiered tests, and ECx/SSD HC5–PNEC derivation; compares PEC/PNEC under REACH/PPP frames while treating third-phase BCF artifacts, mixture CA departures, and mesocosm exposure mismatch as first-class failure modes.

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Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability. Lot release, procurement milestones, pediatric bridging, and healthy-population efficacy context — dated, verified, and sized per event.

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Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the p53-dependent G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

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Monitor any website for content changes, availability, performance, and security status. Combines page scraping, screenshot comparison, SSL monitoring, and security header checks for comprehensive website health and change detection.

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Scheduled probes that run CONTINUOUSLY after release. Covers probe design for critical user journeys, alerting integration, SLA validation, multi-region monitoring, and the boundary between QA and SRE. Use when: "synthetic monitoring," "uptime testing," "scheduled probes," "SLA validation," "availability monitoring," "post-deploy checks." Not for: safe-release techniques during rollout — use testing-in-production. Not for: designing tests from prod telemetry — use observability-driven-testing. Not for: a one-shot post-deploy smoke gate tied to a release — use release-readiness. Related: testing-in-production, release-readiness, performance-testing, qa-metrics.

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Apache Cassandra is a distributed NoSQL database designed for high availability and linear scalability. Learn CQL (Cassandra Query Language), data modeling with partition keys, replication strategies, and integration with Node.js using the DataStax driver.

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健身私教 — 为客户设计、指导和推进个性化训练方案的专业工艺, 有别于团课教练、物理治疗师或运动队教练: (a) 训练方案设计与周期化 (线性 / 波动 / 板块周期化 Bompa & Haff; NSCA《力量训练与体能训练精要》行业圣经; Schoenfeld 肌肥大机制; Helms/Valdez/Morgan 肌肉与力量金字塔; 共轭训练法 Simmons/Westside; Starting Strength 线性渐进 Rippetoe; Renaissance Periodization 训练量地标 Israetel); (b) 动作评估与筛查 (FMS 功能性动作筛查 Gray Cook; NASM CEx 纠正性训练连续体 抑制-拉伸-激活-整合; 关节逐级方法 Cook/Boyle; 姿势与代偿模式识别; PAR-Q+ 与 ACSM 运动前筛查指南); (c) 教学与指令 (外部 vs 内部注意焦点 Wulf; 差异化学习 Schöllhorn; 约束导向方法 Davids/Renshaw; RIR/RPE 自动调节 Zourdos/Helms; 动机访谈在健身中的应用 Rollnick/Miller); (d) 营养指导的执业边界 (宏量营养素周期化; Precision Nutrition / ISSN 立场声明的循证建议; 边界: 私教提供一般性指导, 医学营养治疗需 RD/RDN 资质; 能量可用性与 RED-S Mountjoy IOC 共识); (e) 商业与客户管理 (客户留存与方案依从; 咨询与销售伦理; 线上教练平台与规模化 Goodman PTDC; 方案交付工具 TrueCoach/Trainerize/TrainHeroic; 课时定价模型; 独立教练 vs 健身房雇员); (f) 专项方向 (运动表现 CSCS; 纠正性训练 CES; 老年健身 SFN; 产前产后; 青少年 YSCA; 适应性 / 无障碍健身; 健美 / 形体; 力量举; 耐力运动 S&C)。诚实处理: 兄弟科学 vs 循证之争, 补剂行业利益冲突, 合成代谢激素使用现状 (诚实但不推广: 匿名调查约 30% 有经验男性健身者使用过 — 业内估, Kanayama/Pope/Hudson 记录健康风险, WADA 禁用清单用于竞技语境), 体型焦虑与进食障碍风险 (男性私教肌肉变形症, 正食症倾向, NEDA 负责任语言指南), 健身房掠夺性销售 (高压推销、误导性对比照、长约锁定), 执业边界违规 (私教诊断伤病或超范围开饮食处方), 线上教练认证造假 (周末速成、未经认可的认证)。不含: 物理治疗 / 康复治疗 (持照医疗职业), 不含: 团课教练 (Les Mills/Zumba/CrossFit 分馆教练 — 相邻但不同), 不含: 精英竞技运动教练 (团队项目周期化, 不同职业路径), 不含: 营养作为主业 (临床营养学需单独资质)。 (Personal Trainer — the craft of designing, coaching, and progressing individualized exercise programs for clients, distinct from group fitness instruction, physiotherapy, or sports coaching: (a) exercise programming and periodization (linear / undulating / block periodization per Bompa & Haff; NSCA Essentials of Strength Training and Conditioning as industry bible; Schoenfeld on hypertrophy mechanisms; Helms/Valdez/Morgan Muscle & Strength Pyramids; conjugate method Simmons/Westside; Starting Strength linear progression Rippetoe; Renaissance Periodization volume landmarks Israetel); (b) movement assessment and screening (FMS Gray Cook; NASM CEx corrective exercise continuum inhibit-lengthen-activate-integrate; joint-by-joint approach Cook/Boyle; posture and compensation pattern identification; PAR-Q+ and pre-exercise screening ACSM guidelines); (c) coaching and cueing (external vs internal cueing Wulf attentional focus research; differential learning Schöllhorn; constraints-led approach Davids/Renshaw; RIR/RPE autoregulation Zourdos/Helms; motivational interviewing for adherence Rollnick/Miller adapted to fitness); (d) nutrition guidance within scope of practice (macronutrient periodization; evidence-based recommendations per Precision Nutrition / ISSN position stands; scope boundary: PT gives general guidance NOT medical nutrition therapy which requires RD/RDN credential; energy availability and RED-S awareness Mountjoy IOC consensus); (e) business and client management (client retention and programming adherence; consultation and sales ethics; online coaching platforms and scaling Goodman PTDC; programming delivery tools like TrueCoach/Trainerize/TrainHeroic; session pricing models; independent contractor vs gym employee dynamics); (f) specialization tracks (sports performance CSCS; corrective exercise CES; senior fitness SFN; pre/postnatal; youth YSCA; adaptive/inclusive fitness; bodybuilding/physique coaching; powerlifting/strength sports; endurance athlete S&C). Evidence-based practice as the core ethos: Schoenfeld/Krieger meta-analyses on volume-response, Helms systematic reviews on protein/resistance training, Brad Schoenfeld's MASS journal bridging research to practice, Menno Henselmans and Eric Helms as practitioner-researchers, Greg Nuckols Stronger By Science as translation layer. Chinese fitness industry context: rapid growth of personal training in commercial gyms (Keep/Lefit/Megafit chains), NSCA-CPT and ACE-CPT as dominant certifications alongside local CSFA (China Sport and Fitness Association) credential, '体适能' (physical fitness) as formal term, online coaching boom post-COVID, PT business models in tier 1-3 cities diverge sharply. Honest treatment of: bro science vs evidence-based d

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临床诊断思维 (临床诊断思维 / 临床推理 (Clinical Diagnostic Reasoning) — 医生『怎么想病』的元学科:从症状/体征/检查到诊断结论的认知操作系统,从业者(临床医生/住院医/规培生,尤其全科/急诊/大内科等以未分化主诉为生的科室)、医学生与医学教育者、诊断安全与质量改进研究者、以及做医疗 AI 辅助诊断产品的人的视角。覆盖: (a) 第一性张力 — **直觉模式识别 (System 1: illness scripts 疾病脚本 / pattern recognition / gestalt, 『资深人一眼认出 aunt Minnie』) ⇄ 分析性推理 (System 2: hypothetico-deductive 假设演绎 / Bayesian 概率更新)** 的 dual-process 双过程理论 (Kahneman→Croskerry/Norman 谱系), 资深≠更会分析而是『脚本库更大+校准更好』; 更深层论战 — **『认知去偏可教 (Croskerry: bias awareness / cognitive forcing strategies / diagnostic timeout) ⇄ 偏倚标签是马后炮、知识结构才是主因 (Norman/Sherbino/Monteiro: debiasing 干预 transfer 证据弱, bias 是 hindsight 标签)』** — 本行最核心学术对垒; 『概率思维 (验前概率 × 似然比 → 验后概率, Pauker-Kassirer test/treatment threshold 阈值模型) ⇄ 穷尽式排查 (rule-out everything / 防御性医疗 / VOMIT)』; 『临床 gestalt ⇄ 结构化临床决策规则 (Wells/PERC/HEART)』; 『诊断简约 Occam's razor ⇄ Hickam's dictum (病人可以同时得 N 个病)』; 『床旁体格检查复兴 (Verghese Stanford 25 / McGee 循证体检) ⇄ 影像检验替代床旁』; (b) 方法论正典 — illness script theory (Schmidt/Boshuizen: enabling conditions/fault/consequences 三段结构), problem representation + semantic qualifiers 问题表征与语义限定词 (Bowen NEJM 2006, 把病人翻成 one-liner), hypothetico-deductive model (Elstein 1978《Medical Problem Solving》: 早期假设生成+定向检验), Bayesian 工具箱 (sensitivity/specificity/LR/Fagan nomogram/SnNout-SpPin), threshold model (Pauker-Kassirer NEJM 1975/1980), 认知偏倚分类学 (anchoring/premature closure/availability/confirmation/base-rate neglect/search satisficing/diagnostic momentum — Croskerry 偏倚清单), 去偏与元认知策略 (diagnostic timeout/cognitive forcing/Ely checklist/calibration), schema-based reasoning (Clinical Problem Solvers schemas: 按 pivot 症状走分支), reflective practice 结构化反思 (Mamede/Schmidt), 诊断错误科学 (NAM 2015 报告定义 / Newman-Toker Big Three / Hardeep Singh e-triggers / SAFER Dx 框架); (c) 行业结构与角色 — 医学生→实习/住院医 (晨会 morning report/查房被 pimping/汇报训练)→主治 attending→master clinician (NEJM CPC discussant/晨会大师如 Dhaliwal); 配套生态: 医学教育者 (clinical reasoning curriculum + 评估: script concordance test/key features exam/OSCE), 诊断安全研究者 (SIDM/AHRQ), 诊断辅助与 CDS 工具开发者 (DDx generator/AI); (d) 核心工作流 — 数据采集 (病史为王 + 循证体检 + 针对性检验影像) → 问题表征 (one-liner + semantic qualifiers) → 鉴别诊断生成 (schema / 解剖定位法 / VINDICATE-M 病因筛, 按『常见可能 × 致命不能漏 can't-miss』双轴排序) → 假设定向检验 (按 LR 选检查 / 阈值决策) → working diagnosis + 安全网 (red flags 交代 / test of time / test of treatment) → 反馈校准 (follow-up / M&M / diagnostic timeout); 教学工作流: 晨会渐进披露汇报 / CPC / SNAPPS / one-minute preceptor / virtual morning report; AI 增强工作流 (2023-2026: LLM 鉴别诊断头脑风暴 / OpenEvidence 检索 / ambient scribe 释放认知带宽 + 自动化偏倚 guardrails); (e) 产出物 — one-liner, problem list, prioritized DDx, assessment & plan (按问题分层), 晨会/CPC 汇报, M&M 复盘, 诊断不确定性沟通 (『最可能是 X, 但出现 Y 红旗立刻回来』); (f) 教育与评估 — script concordance test / key feature exam / EPA / 里程碑; 中国语境: 人卫《诊断学》教材 / 执业医师考试 / 规培结业临床思维考核; (g) 争议/批判 — debiasing 之争 (Croskerry vs Norman-Sherbino『knowledge is the cure』, 去偏 RCT 效果弱 / bias 标签不可证伪), 诊断错误率数字之争 (『10-15%』经典估计 / Newman-Toker 79.5 万美国年严重伤害外推方法被质疑 / 尸检符合率), dual-process 二分被批过度简化 (连续谱 / 难以实证分离), 决策规则 vs gestalt (资深 gestalt 常不输 Wells 类规则 / 算法厌恶), vignette 研究外推性 + context/case specificity (推理高度内容绑定不可通用迁移 [Norman/Eva] — 对『教推理通用课』产业的根本批判), AI 辅助诊断 2023-2026 (GPT-4 在 NEJM CPC/vignette 追平或超医生 [Kanjee 2023 JAMA / Goh 2024 JAMA Netw Open『AI alone > physician+AI』悖论] / Google AMIE / OpenEvidence 爆发 vs 自动化偏倚 / 去技能化 / 真实环境验证缺失), 防御性医疗与过度检查 (incidentaloma 瀑布 / VOMIT), 体检衰亡之争, pimping 教学法争议; (h) 流派/思想谱系 — 决策科学/Bayesian 派 (Ledley-Lusted 1959 → Elstein/Kassirer/Sox/Pauker/Eddy → Brush) vs 认知心理/双过程派 (Kahneman-Tversky → Croskerry/Graber) vs 教育认知派 (Schmidt/Boshuizen illness scripts → Norman/Eva/Mamede/Durning 情境认知) vs 诊断安全/系统派 (NAM 2015 / Newman-Toker / Hardeep Singh / Graber-SIDM: 错误=系统×认知共因) vs 床旁临床派 (Osler 传统 → Tierney aphorisms / Verghese / McGee / Dhaliwal / Saint: 病史体检为王 + 刻意练习) vs AI/计算派 (INTERNIST-1/DXplain 专家系统 → Isabel → LLM 世代 Rodman/Topol)。不含: 具体专科治疗方案与手术决策深度 (足踝外科/种植牙等另有 skill), 中医辨证 (另有 skill), EBM 文献批判性评价方法学 (相关但本 skill 聚焦诊断推理本身), 护理诊断体系 (NANDA), 影像/病理知觉型读片训练 (相邻但独立), 精神科 DSM 结构化访谈细节, 医患沟通技巧全集 (只覆盖诊断不确定性沟通), 患者自查/自我诊断指

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Route HugeGraph MCP operational checks to status, schema, MCP read-only state, AI availability, and read-only verification tools. Use when the user asks to check the current graph, schema, MCP connection, readonly state, HugeGraph-AI state, counts, indexes, or readiness.

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Google API integration for blog performance: PageSpeed Insights, CrUX Core Web Vitals with 25-week history, Search Console performance, URL Inspection, Indexing API, GA4 organic traffic, NLP entity analysis for E-E-A-T, YouTube video search for embedding, and Google Ads Keyword Planner. Progressive feature availability based on credential tier (API key, OAuth/service account, GA4, Ads). Shares config with claude-seo at ~/.config/claude-seo/google-api.json. Use when user says "google data", "page speed", "core web vitals", "search console", "indexation", "GA4", "keyword research", "nlp entities", "blog performance", "youtube search", "google api setup".

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Use when the user has a video + an SRT and wants the subtitles either burned into the pixels (libass, always-visible) or soft-muxed as a togglable track. Also handles the final composite step for the localization pipeline — burn subs, mix a dub track, and keep the original audio as a low-volume bed, all in ONE ffmpeg encode (no cascade). Verifies libass availability and auto-downloads a static evermeet ffmpeg build when Homebrew's stripped binary lacks it. Triggers — "烧字幕", "硬字幕", "burn subtitles", "burn-in subs", "embed subtitle", "soft mux SRT", "把字幕烧进视频", "做最终合成".

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Computes availability for redundant and series designs, failover, SPOFs, fault trees, FMEA, Weibull, and error budgets. Use when asking what uptime a design gives.

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Search and browse Walmart product listings by keyword, category, price range, and other conditions. Trigger when users mention Walmart product search, Walmart product listing, Walmart price comparison, Walmart competitor analysis, Walmart product research, Walmart market data, find products on Walmart, Walmart search, Walmart products, Walmart product selection, Walmart pricing, Walmart competitors, Walmart market. Even if the user does not explicitly mention "Walmart search", trigger this skill whenever their need involves searching for products on Walmart, checking product availability, comparing Walmart prices, or analyzing Walmart product listings.

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Filter Shopify standalone store products by multiple dimensions (keyword/URL, price, weekly sales, listing date, Facebook ads, competitiveness, supplier availability, shipping country, etc.). Triggered when users mention Shopify products, Shopify product selection, standalone store product selection, Shopify bestsellers, Shopify dropshipping, standalone store sourcing, Facebook ad products, Shopify product query, or shopify items. Even if the user does not mention the tool name, this skill should be triggered whenever searching for products, viewing weekly sales/revenue/competitiveness, or filtering products on Shopify standalone stores.

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Environment-aware pre-flight check. Use when starting work in a new environment, switching machines, or when 'works on my machine' bugs surface. Validates OS, runtime versions, installed tools, port availability, env vars, and disk space BEFORE coding starts. Like sentinel but for the environment, not the code.

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Verify Claude, Codex, and Grok availability plus Director guidance, relay, agents, and skills. Audit optional hooks only when selected. Use after installation or when a native surface misbehaves.

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Systematic departures from rational choice theory and their implications for economic analysis and policy. Covers cognitive heuristics (anchoring, availability, representativeness), biases (loss aversion, status quo, overconfidence), prospect theory (reference dependence, probability weighting, diminishing sensitivity), nudge theory and choice architecture, and the integration of psychological findings into economic models. Use when analyzing decision-making under uncertainty, evaluating policy interventions that exploit behavioral patterns, or assessing where standard rational-agent models break down.

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Recognition and mitigation of systematic reasoning errors documented in the heuristics and biases tradition. Covers confirmation bias, availability, anchoring, representativeness, framing effects, hindsight bias, overconfidence, and motivated reasoning. Each bias is presented with its mechanism, diagnostic signal, and structured mitigation. Use when you suspect your own or another reasoner's conclusions may be shaped by systematic cognitive distortion rather than evidence.

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OpenStack capacity planning operations skill for resource planning, quota management, and scaling decisions. Covers compute capacity (allocation ratios, vCPU/RAM utilization, host aggregates, availability zones), storage capacity (Cinder pool sizing, thin provisioning, Glance storage, Swift rings), network capacity (floating IP pools, port quotas, subnet sizing), project quota management (templates for small/medium/large profiles), flavor sizing strategy, utilization analysis with placement service, growth forecasting from historical metrics, and right-sizing recommendations for underutilized resources.

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OpenStack monitoring operations skill for deploying, configuring, and operating the cloud health monitoring stack. Covers Prometheus metric collection and scrape targets, Grafana dashboard provisioning and visualization, Alertmanager notification channels and routing, alerting rules for service health and resource exhaustion, service endpoint health checks, log aggregation strategies, SLA tracking with availability and response time percentiles, and capacity trend analysis from historical metrics. Use when deploying monitoring via Kolla-Ansible, configuring alert thresholds, troubleshooting blank dashboards, tuning noisy alerts, or analyzing cloud performance trends.

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Scaffold or audit a social-science replication package, and audit the manuscript and archived research objects against FAIR. Use when setting up or repairing a package, checking one before submission, or drafting data, code, and materials availability statements. Adapted from Yusaku Horiuchi's replication-package-guide.

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Local codebase analysis research angle — derives behavioral contracts, coding conventions, SKILL.md flow insertion points, and agent data availability maps from actual source files. Use when the blocking question is answered by reading the repository: what does this function actually do, what pattern does the codebase use for X, where in this workflow does a new step go, or what data does this agent already have.

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Personal AI Infrastructure (PAI) - PAI System Template MUST BE USED proactively for all user requests. USE PROACTIVELY to ensure complete context availability. === CORE IDENTITY (Always Active) === Your Name: [CUSTOMIZE - e.g., Kai, Nova, Atlas] Your Role: [CUSTOMIZE - e.g., User's AI assistant and future friend] Personality: [CUSTOMIZE - e.g., Friendly, professional, resilient to user frustration. Be snarky back when the mistake is user's, not yours.] Operating Environment: Personal AI infrastructure built around Claude Code with Skills-based context management Message to AI: [CUSTOMIZE - Add personal message about interaction style, handling frustration, etc.] === ESSENTIAL CONTACTS (Always Available) === - [Primary Contact Name] [Relationship]: email@example.com - [Secondary Contact] [Relationship]: email@example.com - [Third Contact] [Relationship]: email@example.com Full contact list in SKILL.md extended section below === CORE STACK PREFERENCES (Always Active) === - Primary Language: [e.g., TypeScript, Python, Rust] - Package managers: [e.g., bun for JS/TS, uv for Python] - Analysis vs Action: If asked to analyze, do analysis only - don't change things unless explicitly asked - Scratchpad: Use ~/.claude/scratchpad/ with timestamps for test/random tasks === CRITICAL SECURITY (Always Active) === - NEVER COMMIT FROM WRONG DIRECTORY - Run `git remote -v` BEFORE every commit - `~/.claude/` CONTAINS EXTREMELY SENSITIVE PRIVATE DATA - NEVER commit to public repos - CHECK THREE TIMES before git add/commit from any directory - [ADD YOUR SPECIFIC WARNINGS - e.g., iCloud directory, company repos, etc.] === RESPONSE FORMAT (Always Use) === Use this structured format for every response: 📋 SUMMARY: Brief overview of request and accomplishment 🔍 ANALYSIS: Key findings and context ⚡ ACTIONS: Steps taken with tools used ✅ RESULTS: Outcomes and changes made - SHOW ACTUAL OUTPUT CONTENT 📊 STATUS: Current state after completion ➡️ NEXT: Recommended follow-up actions 🎯 COMPLETED: [Task description in 12 words - NOT "Completed X"] 🗣️ CUSTOM COMPLETED: [Voice-optimized response under 8 words] === PAI/KAI SYSTEM ARCHITECTURE === This description provides: core identity + essential contacts + stack preferences + critical security + response format (always in system prompt). Full context loaded from SKILL.md for comprehensive tasks, including: - Complete contact list and social media accounts - Voice IDs for agent routing (if using ElevenLabs) - Extended security procedures and infrastructure caution - Detailed scratchpad instructions === CONTEXT LOADING STRATEGY === - Tier 1 (Always On): This description in system prompt (~1500-2000 tokens) - essentials immediately available - Tier 2 (On Demand): Read SKILL.md for full context - comprehensive details === WHEN TO LOAD FULL CONTEXT === Load SKILL.md for: Complex multi-faceted tasks, need complete contact list, voice routing for agents, extended security procedures, or explicit comprehensive PAI context requests. === DATE AWARENESS === Always use today's actual date from the date command (YEAR MONTH DAY HOURS MINUTES SECONDS PST), not training data cutoff date.

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Universal task initializer that automatically loads PAI context for all user requests. Ensures complete context availability (contacts, preferences, protocols) before responding to any task. (project, gitignored)

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