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UMAP dimensionality reduction. Fast nonlinear manifold learning for 2D/3D visualization, clustering preprocessing (HDBSCAN), supervised/parametric UMAP, for high-dimensional data.

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Orchestrates the full path from differential expression results to redundancy-collapsed functional enrichment: choose ORA vs GSEA, convert gene IDs per method, run enrichGO/enrichKEGG/enrichPathway/enrichWP or gseGO/gseKEGG (clusterProfiler, ReactomePA, rWikiPathways), and visualize. Use when a DESeq2/edgeR/limma result must become enriched GO terms, KEGG/Reactome/WikiPathways pathways, or a GSEA leading edge; when the input is a full ranking for all genes (GSEA, named decreasing vector) or only a pre-selected list (ORA plus a defensible background universe); or when assembling DE-to-pathway end to end. The DE list and ranking statistic come from differential-expression/de-results; per-method nuance lives in the pathway-analysis skills.

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End-to-end copy number variant detection workflow from BAM files. Covers CNVkit analysis for exome/targeted sequencing with visualization and annotation. Use when detecting copy number alterations from sequencing data.

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End-to-end alternative splicing analysis from FASTQ to differential splicing results for short-read bulk RNA-seq. Aligns with STAR 2-pass cohort-style, performs junction QC (RSeQC, MaxEntScan, SpliceAI), runs rMATS-turbo and leafcutter for concordant differential analysis, optionally MAJIQ V3 for complex events / heterogeneous cohorts, isoform-switching with NMD/ORF/domain consequences (IsoformSwitchAnalyzeR v2 + DRIMSeq+DEXSeq+stageR DTU), and sashimi visualizations. Use when performing comprehensive splicing analysis from raw bulk RNA-seq data; for variant-driven splice prediction see splice-variant-prediction; for rare-disease single-patient outlier detection see outlier-splicing-detection; for full-isoform PacBio/ONT analysis see long-read-splicing.

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Multi-method binding pocket detection and druggability assessment. Grid-based, fpocket, and P2Rank detection with druggability scoring, visualization, and cross-structure comparison.

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Improve layout composition, spacing systems, grouping, and visual rhythm. Use when the user mentions weak layout structure, arbitrary spacing, weak grouping, crowded composition, or layout monotony rather than priority/emphasis problems.

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Reduce visual intensity, saturation, and noise while preserving hierarchy and character. Use when the structure is basically sound but the design feels too loud, bold, garish, aggressive, or overstimulating—not when the real problem is structural clutter, too many features, or not enough personality.

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Create standout, technically ambitious interfaces that feel extraordinary through cinematic transitions, advanced motion, heavy rendering, or other high-ambition implementation work. Use when the user wants to wow, impress, go all-out, or push a feature beyond conventional UI polish—not when simple visual confidence or routine cleanup is enough.

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Add moments of joy, personality, and surprise through success states, empty states, loading moments, hover details, and celebratory polish once the fundamentals already work. Use when the user wants delight, charm, personality, or memorable micro-interactions—not when the main need is baseline cleanup or stronger visual impact.

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Simplify cluttered UI by removing unnecessary elements, choices, features, and structural complexity. Use when the problem is too many controls, options, features, or competing elements—not when the structure is sound and the real issue is only visual intensity or lack of personality.

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Increase visual impact, contrast, personality, and compositional confidence when a design feels bland, generic, or too safe. Use when the design needs more energy, confidence, or memorability—not when the real problem is clutter, over-intensity, or micro-detail polish.

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Design charts, metrics, and data tables that help users interpret and compare data. Use when the user asks to visualize data, choose chart types, improve dashboard analytics, or make data presentation accessible. Dashboard navigation and shell layout alone belong to add-ui or arrange.

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Improve how interfaces use photos, screenshots, icons, illustrations, and user-uploaded media so visuals support clarity instead of undermining it. Use when the user mentions images, screenshots, background photos, hero images, icon sizing, user-uploaded media, crops, overlays, or image readability.

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Run technical quality checks across accessibility, performance, theming, responsive design, and anti-patterns. Generates a scored report with P0-P3 severity ratings and actionable plan. Use when the user wants measurable accessibility, performance, responsive, theming, or anti-pattern findings—not when they mainly want an overall UX critique or final visual/detail polish.

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Clarify priority and emphasis by fixing unclear primary actions, competing visual weight, loud section titles, and weak label/value treatment. Use when the user mentions hierarchy, prioritization, too much competition, grayscale confusion, loud headings, or unclear primary actions.

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Before any PR that touches frontend, run the app and visually verify PT/EN pages on mobile and desktop. Use when finishing UI work or opening a frontend PR.

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Pre-PR verification for VenTu — tests, data validation, static build, and e2e for the touched surface. Use before opening any PR. For visual UI checks also load ventu-verify-ui.

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Guidance for distinctive, intentional visual design when building new UI or reshaping an existing one. Helps with aesthetic direction, typography, and making choices that don't read as templated defaults.

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Define or review a visual system, DESIGN.md, or redesign direction. Use for typography, layout, color, motion, and interaction design decisions.

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Build AI data analysis assistants with visualization. TRIGGERS - Use when user needs help with ai-data-analyst related tasks.

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Generate a visual KPI report card with a headline metric, secondary stats, and branding — shareable as an image.

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Draws debug overlays in a running CARLA world via world.debug — points, lines, arrows, bounding boxes, and text strings, each with a colour and lifetime. Use when the user asks to "draw/mark/highlight a point or box in the world", "visualise a path/waypoints", "label a location", or "show something on the map for debugging". Shapes are an overlay, not actors.

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Windows アプリ開発 (WinUI 3 / XAML) の UI 基盤リファレンス。 Grid, StackPanel, Canvas, RelativePanel, SplitView, ScrollViewer、x:Bind, x:Name, x:Class, StaticResource, ThemeResource、添付プロパティ, 依存関係プロパティ、Style, ControlTemplate, DataTemplate, VisualStateManager, ResourceDictionary、Acrylic, Mica, SystemBackdrop, SystemBackdropElement、compact sizing、Binding, INotifyPropertyChanged, ObservableCollection, IValueConverter, DataContext, MVVM、 Storyboard, DoubleAnimation, EasingFunction, ThemeTransition, ConnectedAnimation, ImplicitAnimation、XamlOptionalChanges。

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Windows アプリ開発 (DirectX / WinRT メディア) のグラフィックス・メディア API リファレンス。 Direct2D (ID2D1Factory, ID2D1DeviceContext, ID2D1Bitmap1, ID2D1Effect, D2D1 Effects, ID2D1PathGeometry), DirectWrite (IDWriteFactory, IDWriteTextLayout, DWriteCore), Direct3D 11/12 (D3D11CreateDevice, D3D11On12, DXGI SwapChain, HLSL, D3D12 PipelineState, D3D12 DRED), Microsoft.UI.Composition (Compositor, Visual, ExpressionAnimation, InteractionTracker, MicaController), カメラ・画面キャプチャ (MediaCapture, MediaFrameReader, GraphicsCaptureSession, Windows Studio Effects, OpenCV)、音声・動画再生 (MediaPlayer, MediaPlaybackSession, AudioGraph, MediaTranscoder, AdaptiveMediaSource, HLS, DASH, CastingDevicePicker, AudioPlaybackConnection)。

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