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Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features directory, MUI v7 styling, TanStack Router, performance optimization, and TypeScript best practices. Use when creating components, pages, features, fetching data, styling, routing, or working with frontend code.
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Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.
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Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary). Use when downloading sequences, fetching GenBank/GenPept records, getting document summaries, parsing nested XML, navigating GI deprecation, choosing between rettype+retmode combinations, and parsing into Biopython SeqRecord/SwissProt objects. Covers nucleotide, protein, gene, pubmed, sra, gds, taxonomy, snp, clinvar.
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Expert guidance for Fully Sharded Data Parallel training with PyTorch FSDP - parameter sharding, mixed precision, CPU offloading, FSDP2
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Reference for producing Adobe Document Authoring (DA, da.live) and Edge Delivery Services (EDS, aka aem.live/Helix) compatible content. Use whenever generating HTML for DA upload, uploading media binaries to DA, publishing to aem.live, or driving the DA admin API (auth, source PUT, preview/publish). Covers block HTML format (canonical div-class form and accepted table alternate), section structure, page/section metadata, icons, links, images, default content, document skeleton constraints, block cell content normalization, the DA Source API contract, IMS auth, media storage, supported formats, Media Bus vs Content Bus delivery, and silent-failure rules that corrupt content.
中文简介正在准备中。当前显示原文说明。
Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.
中文简介正在准备中。当前显示原文说明。
Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary). Use when downloading sequences, fetching GenBank/GenPept records, getting document summaries, parsing nested XML, navigating GI deprecation, choosing between rettype+retmode combinations, and parsing into Biopython SeqRecord/SwissProt objects. Covers nucleotide, protein, gene, pubmed, sra, gds, taxonomy, snp, clinvar.
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next/dynamic code splitting and build-graph cost; first stop for build failures. Use before lazy-loading or deferring a heavy component, adding a dynamic import, React.lazy, or ssr: false; on 'window is not defined' or a hydration mismatch; shrinking the bundle; or on 'build failed', OOM, SIGKILL, a slower build, or 'Collecting page data'.
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When the user needs to set up multiple academic courses in a learning management system (Canvas/LMS) from structured data sources. This skill automates the entire workflow extracting course schedules from emails/attachments, matching instructors from CSV files, creating courses, enrolling teachers, publishing announcements with class details, uploading syllabi, enabling resource sharing for instructors teaching multiple courses, and publishing all courses. Triggers include course schedule setup, Canvas/LMS administration, academic term preparation, instructor assignment, syllabus distribution, and multi-course management.
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Use this skill when building or debugging table usage with nuxt-ui-tools as a package consumer. Covers defineTableSchema, useTable, DataList, granular composition, columns, filters, sorting, offset or cursor loading, layouts, summary rows on phones, first-use empty states, actions, selection, accessible row names, context, and URL state with concrete examples.
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Use this skill when building analytics dashboards with nuxt-ui-tools as a package consumer. Covers schema and view functions (defineDashboardSchema, defineDashboardView) that take their context as typed params, useDashboard with a getter that rebuilds on input change, typed injection (useDashboardView, injectDashboard, InferDashboard, InferDashboardView), filters declared inline with the f builder and synced with the URL, memory, or an external store (one value per key across views), headless filters, filter controls and the shipped UI (UiDashboardPage, UiDashboardFilters, UiDashboardFilter, UiDashboardViewTabs) with slot overrides, remote paginated pickers and remoteTableOptions, staged queries (essential / background / deferred) with select and dependent requires, lazy enabled conditions on views, queries, and filters (blocks of disabled queries hidden, grids closing up), derived values, views (tabs), query-scoped filters, number formats (presets, Intl options, useDashboardFormat), and the dashboard blocks (stats with trends, goals, and comparisons, stat groups, gauges, unovis charts with highlights, value labels, and totals, lists with progress rings, bars, funnel, alerts, activity feeds, sortable tables, custom widgets) with their automatic loading, error, empty, and refresh states, card menus, header and footer actions, row actions, drill-down and selected state, card tabs, split cards, comparison periods, auto-refresh, and data freshness.
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Reference for producing Adobe Document Authoring (DA, da.live) and Edge Delivery Services (EDS, aka aem.live/Helix) compatible content. Use whenever generating HTML for DA upload, uploading media binaries to DA, publishing to aem.live, or driving the DA admin API (auth, source PUT, preview/publish). Covers block HTML format (canonical div-class form and accepted table alternate), section structure, page/section metadata, icons, links, images, default content, document skeleton constraints, block cell content normalization, the DA Source API contract, IMS auth, media storage, supported formats, Media Bus vs Content Bus delivery, and silent-failure rules that corrupt content.
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Comprehensive Windows privilege escalation methodology for offensive security engagements. Covers the full attack surface from a standard user shell to NT AUTHORITYSYSTEM: token impersonation via SeImpersonate and SeAssignPrimaryToken privileges using JuicyPotato, PrintSpoofer, GodPotato, SweetPotato, and RoguePotato; service misconfigurations including unquoted service paths, weak service DACLs, writable service binaries, and insecure service creation permissions; AlwaysInstallElevated MSI exploitation; DLL hijacking through search order abuse, phantom DLL loading, and writable PATH directory injection; UAC bypass techniques via fodhelper.exe, eventvwr.exe, CMSTP, and environment variable manipulation; scheduled task abuse for writable task actions and new task creation; registry autorun exploitation for persistence and escalation; PrintNightmare (CVE-2021-34527) for remote and local privilege escalation; and credential harvesting from SAM database extraction, DPAPI blob decryption, LSA secret dumping,...
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Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features directory, MUI v7 styling, TanStack Router, performance optimization, and TypeScript best practices. Use when creating components, pages, features, fetching data, styling, routing, or working with frontend code.
中文简介正在准备中。当前显示原文说明。