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"Apply the Bass Diffusion Model (1969) to forecast innovation adoption using innovation and imitation coefficients. Use this skill when the user needs to forecast new product adoption curves, estimate market penetration timing, calibrate launch strategy based on diffusion dynamics, or when they ask 'how fast will this spread', 'when does adoption take off', or 'what is the expected S-curve'.".
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Build image generation pipelines with Stable Diffusion, FLUX, ControlNet, LoRA, and ComfyUI workflows. Activate on: image generation pipeline, ComfyUI workflow, ControlNet, LoRA training, diffusion model. NOT for: video generation (ai-video-production-master), image classification (computer-vision-pipeline).
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Geração de imagens com tecnologia de ponta usando Stable Diffusion via HuggingFace Diffusers. Use quando gerar imagens a partir de prompts em texto, realizar tradução de imagem para imagem, inpainting ou construir pipelines de difusão customizados.
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State-of-the-art text-to-image generation with Stable Diffusion models via HuggingFace Diffusers. Use when generating images from text prompts, performing image-to-image translation, inpainting, or building custom diffusion pipelines.
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Build, debug, optimize, and deploy ComfyUI workflows for diffusion image, video, and audio generation. Activate on: ComfyUI workflow, ComfyUI custom node, ComfyUI API, ComfyUI Manager, KSampler, FLUX in ComfyUI, Wan 2.2 ComfyUI, Hunyuan video ComfyUI, LTX video ComfyUI, IPAdapter, ControlNet ComfyUI, Kijai wrapper, ComfyDeploy, RunComfy, ComfyUI security, GGUF quantization, TeaCache, Nunchaku, ACE-Step ComfyUI, F5-TTS ComfyUI, subgraphs ComfyUI. NOT for: A1111/Forge/Invoke (different UIs), training pipelines from scratch, non-diffusion ML models, or general image-API integrations (use generative-video-2026 / generative-music-audio / media-gen-deployment).
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用Python实现文字生成图像、现有图像风格转换和指定区域补全，并指导如何控制构图与风格、调整生成参数及减少内存占用。
Run protein structure prediction, molecular design, and docking tools on Tamarind Bio without a local GPU. Guides tool selection, input validation, job submission, batch processing, and result retrieval through its REST API or MCP server.
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Guides PyTorch model training and fine-tuning, from choosing architectures to configuring optimizers and learning rates. Provides troubleshooting steps for unstable loss and memory shortages, plus methods for improving GPU throughput and comparing experiments.
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Plan how to serve a model on Amazon SageMaker AI. The skill uses model type, traffic, response time, and cost constraints to recommend a deployment route, check instance quotas, and coordinate specialized setup and deployment skills.
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Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
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Battle-tested PyTorch training recipes for all domains — LLMs, vision, diffusion, medical imaging, protein/drug discovery, spatial omics, genomics. Covers training loops, optimizer selection (AdamW, Muon), LR scheduling, mixed precision, debugging, and systematic experimentation. Use when training or fine-tuning neural networks, debugging loss spikes or OOM, choosing architectures, or optimizing GPU throughput.
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Expert AI art prompt engineer for Midjourney and Stable Diffusion. Generates high-quality prompts including unified batch illustrations, marketing designs, interactive compositions, and structured framework prompts with translations.
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Python library for single-particle tracking (SPT) in video microscopy via the Crocker-Grier algorithm. Locate particles (fluorescent spots, colloids, vesicles, cells) per frame, link into trajectories, filter short tracks, and compute MSD for diffusion analysis. 2D/3D with subpixel accuracy; reads TIF stacks, AVI, image series via pims. Use for quantitative SPT and diffusion coefficient extraction from fluorescence or brightfield video.
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Use Diffusion Policy for robot imitation-learning configs, zarr replay data, policy/model interfaces, training/evaluation workflows, and safety-gated real robot operations.
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Use DPM-Solver and DPM-Solver++ single-file samplers for diffusion ODE sampling, PyTorch/JAX integration, ScoreSDE/DDPM examples, and Stable Diffusion acceleration.
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Route Custom Diffusion workflows for concept data prep, diffusers training and SDXL, sample generation, delta tools, and CustomConcept101 evaluation.
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Proteina-Complexa flow-based protein backbone generation with fold-conditioned sampling guidance. Use this skill when: (1) Generating de novo protein backbones with hierarchical fold conditioning, (2) Exploring long-chain backbone generation beyond standard diffusion baselines, (3) Using NVIDIA Proteina-style flow matching workflows for controllable backbone design, (4) Comparing flow-based backbone generation against RFdiffusion or BoltzGen, (5) Prototyping fold-guided backbone campaigns before sequence design. This skill is based on the public NVIDIA Digital Bio Proteina project and uses "Proteina-Complexa" as the BioClaw-facing skill label. For sequence design after backbone generation, use proteinmpnn or solublempnn. For QC thresholds, use protein-design-qc.
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Binder design tool selection and workflow routing guidance. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
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Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.
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Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
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Feature-rich Stable Diffusion Web UI for image generation. Supports txt2img, img2img, inpainting, outpainting, LoRA, extensions, upscaling, and batch processing. Widely used desktop interface with an extensive extension ecosystem and API access.
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Master AI-powered game asset pipelines using ComfyUI, Stable Diffusion, FLUX, ControlNet, and IP-Adapter. Creates production-ready sprites, textures, UI, and environments with consistency, proper licensing, and game engine integration. Use when "AI game art, generate game assets, ComfyUI game, stable diffusion sprites, AI texture generation, character consistency AI, procedural art generation, SDXL game assets, FLUX textures, train LoRA game, AI tileable texture, spritesheet generation, " mentioned.
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Design new proteins that bind a chosen surface, using BindCraft's AlphaFold2-guided hallucination or the RFdiffusion backbone plus ProteinMPNN sequence pipeline. Use this skill to specify a target epitope by hotspot residue, trim a receptor to the region worth designing against, set up a design campaign, and filter the output on the in-silico metrics that predict experimental success — interface predicted TM-score, predicted aligned error at the interface, buried surface area, and shape complementarity. Also trigger on BindCraft, RFdiffusion, ProteinMPNN, minibinder, hallucination, inverse folding, hotspot residue, epitope targeting, ipTM, or de novo binder.
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Generate game sprites, 8-direction turnarounds, walk-cycle sprite sheets, SVG characters, ASCII art and animated mascots from images or descriptions, with September 2026 providers: Retro Diffusion (pixel art, 8-dir rotation, frame animation, free palette tools), fal genmedia (GPT Image 2.5, Nano Banana 2, Kling 3, Seedance 2.5, Wan 3, Hailuo 03). Deterministic utilities: feet-line frame alignment, palette-preserving Scale2x/3x/4x pixel scaler, atlas manifest v2 with states/fps/loop/anchor, Aseprite JSON, pipeline profiles. Triggers on sprite, pixel art, sprite sheet, spritesheet, turnaround, 8-direction, walk cycle, atlas manifest, frame alignment, pixel scaler, Retro Diffusion, genmedia, SVG character, ASCII art, mascot, game asset, sprite pipeline profile.
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