“alignment”的搜索结果

Account-based marketing for B2B SaaS. Use this skill to build a target account list, tier it 1:1 / 1:few / 1:many, size it against sales capacity, turn intent and engagement signals into plays, write the multi-channel orchestration contract each tier runs on, and measure the program in account coverage, penetration and pipeline instead of MQLs. Also triggers on: ABM, account-based marketing, target account list, TAL, named accounts, account tiering, 1:1 ABM, one-to-few, programmatic ABM, account selection, ideal customer profile fit, intent data, buying signals, 6sense, Bombora, Demandbase, account penetration, account coverage, sales and marketing alignment on accounts, enterprise account program.

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リファクタリングを「更新されたチームの理解と、コードが表現する過去の理解の差分同期」と捉え、今回得た新知識（要求・ドメイン知識・制約）が naming と responsibility へ反映されているか、boundary が現在の understanding を表現しているか、diff の削除行やコメントに現れる過去の design history と constraint を失っていないかを diff-time で確認する。Knowledge Delta の signal は diff（追加/削除された hunk・コメント・ADR 参照）を一次情報とし、PR 本文が供給されるときは補助に用い、不確実なら question に留める。ドメイン用語の一貫性は ubiquitous-language-naming、集約/コンテキスト境界の設計判断は bounded-context-language、投機的抽象化・caller special-case は altitude-generalization、スコープ逸脱/前提破壊は fix-scope-integrity、振る舞い変更と構造変更の分離は behavior-structure-separation、完了主張の反証は refactor-claim-audit へ委譲する

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Reads Copilot conversation history and extracts executive-ready success stories. Use when the user asks to study prior Copilot sessions, summarize what was done before, mine evidence, or quantify time, cost, risk, and priority alignment from GitHub Copilot history in any workspace or repository.

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Fit and independently validate rigid scan alignment from named, source traceable correspondences.

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UI visual audit: production-level screenshots, accessibility, alignment, density. Use when implementing, reviewing or testing ui visual audit for React, Vite, Next.js or Perfect_AI projects.

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Use when the user wants to design, redesign, shape, critique, audit, polish, clarify, distill, harden, optimize, adapt, animate, colorize, extract, or otherwise improve a frontend interface. Covers websites, landing pages, dashboards, product UI, app shells, components, forms, settings, onboarding, and empty states. Handles UX review, visual hierarchy, information architecture, cognitive load, accessibility, performance, responsive behavior, theming, anti-patterns, typography, fonts, spacing, layout, alignment, color, motion, micro-interactions, UX copy, error states, edge cases, i18n, and reusable design systems or tokens. Also use for bland designs that need to become bolder or more delightful, loud designs that should become quieter, live browser iteration on UI elements, or ambitious visual effects that should feel technically extraordinary. Not for backend-only or non-UI tasks.

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Reduce OpenClaw token usage and API costs through smart model routing, heartbeat optimization, budget tracking, and native 2026.2.15 features (session pruning, bootstrap size limits, cache TTL alignment). Use when token costs are high, API rate limits are being hit, or hosting multiple agents at scale. The 4 executable scripts (context_optimizer, model_router, heartbeat_optimizer, token_tracker) are local-only — no network requests, no subprocess calls, no system modifications. Reference files (PROVIDERS.md, config-patches.json) document optional multi-provider strategies that require external API keys and network access if you choose to use them. See SECURITY.md for full breakdown.

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Consistent radii, pixel-perfect alignment, state coverage, and the details that signal design quality. Use when polishing designs, auditing quality, or evaluating whether a design is ready to ship.

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Implement, review, or improve SwiftUI features using the iOS 26+ Liquid Glass API. Use when asked to adopt Liquid Glass in new SwiftUI UI, refactor an existing feature to Liquid Glass, or review Liquid Glass usage for correctness, performance, and design alignment.

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Performs a final quality pass fixing alignment, spacing, consistency, and micro-detail issues before shipping. Use when the user mentions polish, finishing touches, pre-launch review, something looks off, or wants to go from good to great.

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Improve layout, spacing, and visual rhythm. Fixes monotonous grids, inconsistent spacing, and weak visual hierarchy. Use when the user mentions layout feeling off, spacing issues, visual hierarchy, crowded UI, alignment problems, or wanting better composition.

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Implement, review, or improve SwiftUI features using the iOS 26+ Liquid Glass API. Use when asked to adopt Liquid Glass in new SwiftUI UI, refactor an existing feature to Liquid Glass, or review Liquid Glass usage for correctness, performance, and design alignment.

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Use this skill when writing, rewriting, or improving marketing copy for any page (homepage, landing page, pricing, feature, product, or about page). This skill produces clear, compelling, and testable copy while enforcing alignment, honesty, and conversion best practices.

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Comprehensive LLM security testing: bias detection, data leakage, prompt injection, jailbreak, alignment testing, adversarial prompts

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Generates complete video ad scripts for 15s, 30s, and 60s formats in Darija (Moroccan Arabic dialect) with shot-by-shot breakdowns, Islamic compliance guidelines, global trend alignment (authenticity, sustainability, UGC), and cultural adaptation for Facebook, Instagram, and TikTok. Includes 4 frameworks including a Moroccan-specific storytelling framework.

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Use when asked to map, crosswalk, align, compare, or gap-analyze any two cybersecurity frameworks, control catalogs, or regulatory requirements using NIST IR 8477 Set-Theory Relationship Mapping (STRM). Triggers on terms like "map controls", "crosswalk", "framework alignment", "gap analysis", or producing a STRM CSV output file.

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End-to-end Ribo-seq analysis from FASTQ through periodicity QC, P-site calibration, ORF detection, translation efficiency, and stalling. Use when orchestrating a full ribosome profiling pipeline and deciding harvest/dedup/alignment options and which downstream analyses the library can support.

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End-to-end ATAC-seq workflow from FASTQ files to differential accessibility and TF footprinting. Covers alignment, peak calling with MACS3, QC metrics, and optional TOBIAS footprinting. Use when running end-to-end ATAC-seq analysis from FASTQ to differential accessibility.

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End-to-end bisulfite sequencing workflow from FASTQ to differentially methylated regions. Covers Bismark alignment, methylation calling, and DMR detection with methylKit. Use when analyzing bisulfite sequencing data.

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Orchestrates an end-to-end long-read structural-variant pipeline - basecalling to minimap2 alignment (platform-matched preset) to Sniffles2/cuteSV/pbsv calling to optional assembly-based calling (dipcall/PAV) to two-step .snf cohort merging to Truvari benchmarking - chaining ONT and PacBio HiFi runs while handing the SV signal mechanism off to the component skills. Use when running a long-read SV workflow from reads to a benchmarked callset, choosing the minimap2 preset and SV caller by platform and goal, deciding when long reads are worth it for the insertions and repeat-mediated SVs short reads physically miss, building a joint-genotyped cohort with the two-step .snf design, or parameterizing a Truvari benchmark against GIAB HG002 Tier 1 plus CMRG. Not for the SV signal mechanism itself (see variant-calling/structural-variant-calling) or short-read SV.

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Orchestrates an end-to-end MeRIP-seq / m6A-seq analysis from raw FASTQ to differential m6A peak calls and metagene plots, chaining fastp adapter trimming, STAR splice-aware alignment (NO deduplication for non-UMI MeRIP), deepTools replicate-concordance + IP-enrichment QC, PreSeq saturation curves, exomePeak2 (transcript-aware Poisson GLM) peak calling, optional MACS3 broad-peak cross-check, DRACH motif confirmation as a sanity check (NOT a per-peak filter), exomePeak2 differential calling via the four-BAM-vector interface (bam_ip + bam_input control; bam_treated_ip + bam_treated_input treatment), ChIPseeker annotation, and the canonical Guitar metagene with stop-codon enrichment as the biological QC anchor. Use when running a complete MeRIP analysis from raw reads, when chaining the constituent epitranscriptomics skills (merip-preprocessing -> m6a-peak-calling -> m6a-differential -> modification-visualization), or when wrapping the pipeline in Snakemake / Nextflow.

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Builds and applies 3D pharmacophore models using RDKit Pharm3D, the apo2ph4 receptor-based workflow (Heider et al 2022/2023 J Chem Inf Model 63:147-158), Pharmer / Pharmit (search), and PharmacoForge (diffusion-based generation, Flynn et al 2025 Front Bioinform), covering ligand-based pharmacophore (from active set alignment) and receptor-based pharmacophore (from binding pocket geometry). Explicit handling of feature types, geometric tolerances, partial matching, and pharmacophore-based virtual screening. Use when identifying scaffold-hopping candidates, building shape-and-feature search queries, or transferring SAR across chemotypes.

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Performs 3D shape-based similarity searching using ROCS (OpenEye), USRCAT (ultra-fast), Open3DAlign (RDKit), ESPSim (electrostatic), and ShaEP with explicit handling of Tanimoto-Combo (shape + color), shape vs ECFP4 complementarity, conformer-ensemble searching, alignment optimization, and scaffold hopping. Use when searching for shape-mimicking compounds with different scaffolds, identifying bioisosteric replacements, prospective scaffold hopping, or expanding hit series beyond 2D similarity.

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Perform a final quality pass fixing alignment, spacing, consistency, and micro-detail issues before shipping. Use when the work is functionally complete and needs finishing touches—not when the hierarchy, structure, tone, or technical foundation still need major changes.

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