“project”的搜索结果

⚠️ DEPRECATED: This SDK has been renamed to Call Automation. For new projects, use azure-communication-callautomation instead. This skill is for maintaining legacy code only.

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Main application building orchestrator. Creates full-stack applications from natural language requests. Determines project type, selects tech stack, coordinates agents.

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Automate Asana tasks via Rube MCP (Composio): tasks, projects, sections, teams, workspaces. Always search tools first for current schemas.

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Build container-based Foundry Agents with Azure AI Projects SDK (ImageBasedHostedAgentDefinition). Use when creating hosted agents with custom container images in Azure AI Foundry.

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Security audit, hardening, threat modeling (STRIDE/PASTA), Red/Blue Team, OWASP checks, code review, incident response, and infrastructure security for any project.

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Discovers, classifies, and masks repetitive elements and transposable elements with RepeatModeler2 (de novo family library), RepeatMasker (masking against a library), EDTA (plant/structural TEs), or EarlGrey (auto-curating wrapper), and quantifies TE expression from RNA-seq with TEtranscripts/SQuIRE. Covers de-novo-library-as-curation-project, soft-vs-hard masking, the domesticated-gene over-masking massacre, Dfam-vs-RepBase, TE classification (Class I/II, family-vs-copy), Kimura repeat landscapes, LAI, and the RNA-seq multimapping problem. Use when masking repeats before gene prediction, building a TE library for a non-model genome, or analyzing transposable-element content or expression.

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Predicts protein-coding gene structures (exons, introns, UTRs) in eukaryotic genomes with BRAKER3 (RNA-seq + protein evidence), BRAKER1/BRAKER2, GALBA (protein-only), Funannotate (fungi), GeMoMa (homology projection), or Helixer/Tiberius (deep-learning ab initio). Covers the evidence-first tool decision, mandatory soft-masking, the training-set-quality-dominates principle, OrthoDB clade-partition selection, the one-isoform-per-locus and missing-UTR traps, merge/split errors, and reference bias against orphan genes. Use when annotating a newly assembled eukaryotic genome, choosing a gene-prediction pipeline based on available evidence, or diagnosing a poor annotation.

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Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.

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Find cross-database references between NCBI databases using Biopython Bio.Entrez (ELink). Use when navigating gene to protein/structure, sequence to publication, PubMed to GEO, BioProject to SRA runs, or discovering all link relationships for a record. Covers linkname semantics, cmd= variants, asymmetric link warnings, neighbor_history for >200 input IDs, and per-database link tables.

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Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Add MAUI DevFlow to a .NET MAUI project with agent package references, MauiProgram.cs registration, Blazor WebView support, GTK variants, Central Package Management guidance, and verification commands. USE FOR: first-time DevFlow setup, reviewing what files to edit, choosing DevFlow packages, or continuing after `maui devflow init` installs skills. DO NOT USE FOR: troubleshooting an already-integrated app that cannot connect, iterative app debugging, UI inspection, or generic MAUI build failures (use maui-devflow-debug). INVOKES: maui devflow CLI and dotnet CLI.

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Expo managed workflow expert for EAS Build, Submit, Update, config plugins, and custom dev clients. Activate on: Expo project, EAS Build, EAS Update, config plugin, expo-dev-client, Expo Router, Expo SDK 52, app.json configuration. NOT for: bare React Native (use react-native-architect), native module authoring (use react-native-architect), Flutter (use flutter-bloc-state-manager).

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Message queues, pub/sub, event sourcing with Kafka, RabbitMQ, Redis Streams. Activate on: event-driven, message queue, pub/sub, Kafka, RabbitMQ, event bus, async messaging, dead letter queue. NOT for: CQRS projections (use cqrs-event-sourcing-architect), real-time WebSocket (use websocket-realtime-expert), observability (use observability-apm-expert).

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Analyze design trends and recommend appropriate styles, color palettes, and typography systems for your project based on current design movements. NOT for accessibility auditing or full design system creation.

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Cloudflare Pages CI/CD with preview environments, edge functions, and Wrangler automation. Activate on: Cloudflare Pages, Wrangler deploy, preview environment, edge function, Pages project, Cloudflare Workers integration, custom domain on Pages. NOT for: Worker-specific development (use cloudflare-worker-dev), DNS management (use devops-automator), full-stack app frameworks (use vercel-deployment).

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Systematic framework for resurrecting and modernizing legacy codebases through archaeology, resurrection, and rejuvenation phases. Activate on "legacy code", "inherited codebase", "no documentation", "technical debt", "resurrect", "modernize". NOT for greenfield projects or well-documented active codebases.

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Refactor apps so backend owns runtime truth and UI only projects snapshots. Use when tools have split authority. NOT for cosmetic UI work or new features before drift is removed.

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Use when building content-heavy sites with Astro, deciding between SSG/SSR/hybrid, choosing client directives (idle/visible/load/media), structuring content collections with type-safe schemas, integrating React/Vue/Solid/Svelte components in the same project, or migrating from Next.js for marketing/docs. Triggers: client:idle vs client:load tradeoffs, content collections schema with zod, image optimization via @astrojs/image, view transitions, server islands, MDX layouts. NOT for SPA-style apps that need full interactivity (use Next/Remix), Astro internals/plugin authoring, or non-content sites where islands provide no benefit.

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Design scheduling agents. Use for timezone-safe negotiation, focus protection, and privacy-safe free-busy handling. NOT for calendar UI, project planning, or general agent architecture.

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The doctrine for turning a vision into a finished, verified, deployed system with near-zero owner involvement. Use when launching, coordinating, resuming, or working any large build, module, campaign, or multi-agent project, or when writing its launch prompt.

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Deploy applications and websites to Vercel using the bundled `scripts/deploy.sh` claimable-preview flow. Use when the user asks to deploy to Vercel, wants a preview URL, or says to push a project live on Vercel.

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Generates creative, research-backed domain name ideas and checks availability with competitor analysis, pattern recognition, and quality scoring. Use when brainstorming brandable domains for a product or project.

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Manage issues, projects & team workflows in Linear. Use when the user wants to read, create or updates tickets in Linear.

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