Design AI evaluation frameworks with benchmarks. TRIGGERS - Use when user needs help with ai-eval-framework related tasks.
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Design AI evaluation frameworks with benchmarks. TRIGGERS - Use when user needs help with ai-eval-framework related tasks.
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Audit AI systems for bias with testing frameworks and mitigation strategies. TRIGGERS - Use when user needs help with ai-bias-auditor related tasks.
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Build A/B testing frameworks for features. TRIGGERS - Use when user needs help with a-b-testing-framework related tasks.
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Use when building PHP applications with modern PHP 8.3+ features, Laravel, or Symfony frameworks. Invokes strict typing, PHPStan level 9, async patterns with Swoole, and PSR standards. Creates controllers, configures middleware, generates migrations, writes PHPUnit/Pest tests, defines typed DTOs and value objects, sets up dependency injection, and scaffolds REST/GraphQL APIs. Use when working with Eloquent, Doctrine, Composer, Psalm, ReactPHP, or any PHP API development.
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Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.
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Detect positive (diversifying / episodic / pervasive) selection using codon dN/dS frameworks. Implements PAML codeml site models (M0/M1a/M2a/M7/M8/M8a), branch models, branch-site model A (Zhang 2005), and HyPhy methods (BUSTED, BUSTED-S, BUSTED-MH, BUSTED-PH, MEME, FEL, FUBAR, aBSREL, SLAC, RELAX, GARD, FUBAR-MH). Includes McDonald-Kreitman framework (asymptotic alpha, impMKT, polyDFE, DFE-alpha, GRAPES) for within-species + divergence inference, RERconverge for trait-correlated rate shifts, CSUBST for convergent substitution, and PhyloAcc for accelerated noncoding evolution. Use when testing adaptive evolution at codons, branches, or full gene; running GARD recombination pre-screen; controlling alignment-error and gBGC false positives; reconciling PAML vs HyPhy results; or performing genome-scale selection scans.
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Analyzes chemical libraries by scaffold using Bemis-Murcko scaffolds, generic frameworks, cyclic skeletons, matched molecular pair (MMP) analysis via mmpdb, R-group decomposition, Free-Wilson analysis, scaffold hopping, and chemotype-aware ML train/test splits. Use when identifying chemotype clusters in a library, deriving SAR transformation rules, decomposing series into R-groups, performing scaffold-balanced QSAR splits, or planning analog campaigns.
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Build robust, production-grade backtesting systems that avoid common pitfalls and produce reliable strategy performance estimates.
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Write comprehensive end-to-end tests that verify complete user workflows, integration between components, and system behavior from user perspective using Playwright, Cypress, or similar frameworks. Use when testing user flows, verifying feature integration, testing across real browsers, ensuring UI interactions work correctly, validating form submissions end-to-end, testing authentication flows, catching regressions, automating QA processes, testing API integrations, or building confidence in production deployments.
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Idiomatic Go - package and interface design, error wrapping, table-driven tests, generics, the modern standard library (slices/maps/cmp/errors.Join), current syntax, and logging discipline. Use when writing, reviewing, or refactoring any Go code, especially code drifting toward Java/Spring shapes (deep layer trees, generic repositories, heavy frameworks) - even if the user never says "idiomatic". Distilled from spf13/go-skills and adapted to this repo.
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Master modern business analysis with AI-powered analytics, real-time dashboards, and data-driven insights. Build comprehensive KPI frameworks, predictive models, and strategic recommendations.
中文简介正在准备中。当前显示原文说明。
Build robust, production-grade backtesting systems that avoid common pitfalls and produce reliable strategy performance estimates.
中文简介正在准备中。当前显示原文说明。
Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.
中文简介正在准备中。当前显示原文说明。
Detect positive (diversifying / episodic / pervasive) selection using codon dN/dS frameworks. Implements PAML codeml site models (M0/M1a/M2a/M7/M8/M8a), branch models, branch-site model A (Zhang 2005), and HyPhy methods (BUSTED, BUSTED-S, BUSTED-MH, BUSTED-PH, MEME, FEL, FUBAR, aBSREL, SLAC, RELAX, GARD, FUBAR-MH). Includes McDonald-Kreitman framework (asymptotic alpha, impMKT, polyDFE, DFE-alpha, GRAPES) for within-species + divergence inference, RERconverge for trait-correlated rate shifts, CSUBST for convergent substitution, and PhyloAcc for accelerated noncoding evolution. Use when testing adaptive evolution at codons, branches, or full gene; running GARD recombination pre-screen; controlling alignment-error and gBGC false positives; reconciling PAML vs HyPhy results; or performing genome-scale selection scans.
中文简介正在准备中。当前显示原文说明。
Analyzes chemical libraries by scaffold using Bemis-Murcko scaffolds, generic frameworks, cyclic skeletons, matched molecular pair (MMP) analysis via mmpdb, R-group decomposition, Free-Wilson analysis, scaffold hopping, and chemotype-aware ML train/test splits. Use when identifying chemotype clusters in a library, deriving SAR transformation rules, decomposing series into R-groups, performing scaffold-balanced QSAR splits, or planning analog campaigns.
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Use when a carrier needs to build an internal dispatcher training program, onboard new dispatchers, or certify dispatcher competency. Covers job description, required skills, training modules, certification frameworks (CDS, CTP), shadowing, evaluation, and career path.
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Use this skill when the user asks about driver discipline — when to coach vs warn vs suspend vs terminate, progressive discipline frameworks, at-will employment in trucking, documenting violations, separating "willful violation" from "human error," and how to handle a driver who refuses corrective action. Reference state employment law + ATA SMP.
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Use this skill when the user asks about cybersecurity for a trucking carrier — protecting ELD data, customer information, financial systems, EDI integrations, fleet telematics, ransomware risk, vendor / shipper data sharing, incident response, and FMCSA cyber-recommendations. Reference NIST + CISA cybersecurity frameworks.
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End-to-end form handling with react-hook-form, Zod schemas, validation patterns, error messaging, field arrays, and multi-step wizards. Use for complex forms, validation architecture, autosave, field dependencies. Activate on "form validation", "react-hook-form", "Zod", "form error", "multi-step form", "wizard". NOT for simple HTML forms, backend validation only, or non-React frameworks.
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Cloudflare Pages CI/CD with preview environments, edge functions, and Wrangler automation. Activate on: Cloudflare Pages, Wrangler deploy, preview environment, edge function, Pages project, Cloudflare Workers integration, custom domain on Pages. NOT for: Worker-specific development (use cloudflare-worker-dev), DNS management (use devops-automator), full-stack app frameworks (use vercel-deployment).
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Plan, evaluate, and adopt agent infrastructure for a named workload. Use for agent runtime/framework selection, agent evaluation or observability plans, memory and tool boundaries, infrastructure cost controls, and organizational adoption. Covers workload-first comparison, risk and recovery planning, held-out evaluation, cost accounting, and staged rollout. Not a vendor ranking or a production certification. NOT for implementing a specific agent behavior (agentic-patterns), building a specific agent (ai-engineer), prompt optimization (prompt-engineer), or conventional ETL workflow design (jury_rig-architect).
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Codified expertise for production scheduling, job sequencing, line balancing, changeover optimization, and bottleneck resolution in discrete and batch manufacturing. Informed by production schedulers with 15+ years experience. Includes TOC/drum-buffer-rope, SMED, OEE analysis, disruption response frameworks, and ERP/MES interaction patterns. Use when scheduling production, resolving bottlenecks, optimizing changeovers, responding to disruptions, or balancing manufacturing lines.
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Codified expertise for returns authorization, receipt and inspection, disposition decisions, refund processing, fraud detection, and warranty claims management. Informed by returns operations managers with 15+ years experience. Includes grading frameworks, disposition economics, fraud pattern recognition, and vendor recovery processes. Use when handling product returns, reverse logistics, refund decisions, return fraud detection, or warranty claims.
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Codified expertise for handling freight exceptions, shipment delays, damages, losses, and carrier disputes. Informed by logistics professionals with 15+ years operational experience. Includes escalation protocols, carrier-specific behaviors, claims procedures, and judgment frameworks. Use when handling shipping exceptions, freight claims, delivery issues, or carrier disputes.
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