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Deep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Illumina, PacBio, and ONT data. Use when calling variants with DeepVariant deep learning caller or when highest germline calling accuracy is required.
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GTM prospecting, enrichment, outreach, and Deepline Play work/audits. Providers: adyntel,affinity,ai_ark,akta,allegrow,amplemarket,apify,attention,attio,aviato,bettercontact,bigquery,bluesky,bounceban,brave,browserbase,builtwith,cbinsights,clay,clickhouse,cloudflare,contactout,contextdev,crunchbase,crustdata-v3,customer_db,databricks,dataforseo,datagma,dealroom,deepline_ip_to_company,deepline_native,deeplineagent,discolike,dnb,dropleads,edges,emailbison,emailguard,enformion,enigma,exa,findymail,firecrawl,fireflies,firmable,forager,fullenrich,fundable,generic_http,getleads,gong,google_ads_audiences,google_workspace,govfiles,grain,hackernews,harvestapi,heyreach,hubspot,hunter,icypeas,instantly,intercom,ipqs,kaspr,kernel,leadmagic,lemlist,limadata,linkedin_ads_audiences,luma,lusha,meta_audiences,millionverifier,nooks,notion,openmart,opensosdata,openwebninja,outreach,parallel,peopledatalabs,pitchbook,podscan,polymarket,postgres,predictleads,prospeo,quickenrich,rapidapi,redshift,rocketreach,salesforce,….
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Use when surfacing architectural friction and proposing deepening refactors (shallow modules → deep modules) for testability and AI-navigability. Triggers on "improve architecture", "find deepening opportunities", "where is this codebase shallow", "architecture review". Emits structured candidates + precise patches; delegates ALL rendering to mk:preview. NOT for diagram/HTML rendering (see mk:preview); NOT for trade-off deliberation (see mk:party); NOT for plan critique (see mk:plan-ceo-review).
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Train Mixture of Experts (MoE) models using DeepSpeed or HuggingFace. Use when training large-scale models with limited compute (5× cost reduction vs dense models), implementing sparse architectures like Mixtral 8x7B or DeepSeek-V3, or scaling model capacity without proportional compute increase. Covers MoE architectures, routing mechanisms, load balancing, expert parallelism, and inference optimization.
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Document a project's structure, commands, and specific conventions in a hierarchy of AGENTS.md files. Analyze directory complexity to choose useful locations, update existing guidance, and check that child files avoid repeating their parents.
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Design modules that hide complex behavior behind a small, clear interface. Use shared design principles to review dependencies, choose where behavior can be swapped, and make code easier to test and maintain.
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Examine recorded calls and voicemails for signs of AI-generated speech. Extract acoustic features, classify samples with machine learning, and prepare reports with confidence scores and sound visualizations to support voice impersonation investigations.
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Build voice applications and phone agents with guidance on OpenAI Realtime API, Vapi, Deepgram, ElevenLabs, and LiveKit. Choose services for speech recognition, voice generation, and live communication, while addressing response delays and interruptions.
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Research markets, competitors, companies, and technical topics using multiple sources in Google NotebookLM. Produce a structured brief with key findings and recommended actions, with optional slides, podcasts, videos, infographics, reports, or mind maps.
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Process large email, document, and transcript archives by routing items to AI models according to their importance. Rule-based privacy checks run before model calls, while extracted information becomes linked knowledge pages with progress checkpoints.
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Add OpenCode as an agent runtime in NanoClaw to use models from OpenAI, Google, OpenRouter, DeepSeek, and other supported services. The skill covers installation, authentication, group selection, and default model changes.
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Review changes of 1,000 lines or more by dividing work across files, focused areas, and commits. Combine several review methods, check consistency across subsystems, verify bug fixes, and report validated findings alongside a checklist showing review coverage.
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Review selected files for bugs by reading full source code, callers, and related implementations. Apply detailed checklists and investigate suspected issues, then report evidence, confidence levels, and suggested fixes.
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Connect streaming APIs to Ant Design X by implementing a Chat Provider, an adapter for request and message formats. Choose built-in providers where suitable, transform custom responses, and configure authentication, retries, and stream parsing.
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[omh] Deep dive before a decision: deep research engine - grounding for specs and decisions: study open-source reference implementations with pinned refs, gather live web evidence with citation discipline, verify contested claims, and distill a decision-grounding dossier that planning consumes; for a decision brief use research-brief, for upstream guidance use web-research. Use when the user says: research plan, literature review, research literature, review recent papers, deep research, deep-research, exhaustive research, saturation research.
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Comprehensive framework for deep analysis of articles, papers, and long-form content using 10+ thinking models (SCQA, 5W2H, critical thinking, inversion, mental models, first principles, systems thinking, six thinking hats). Use when users want to: (1) deeply understand complex articles/content, (2) analyze arguments and identify logical flaws, (3) extract actionable insights from reading materials, (4) create study notes or learning summaries, (5) compare multiple sources, (6) transform knowledge into practical applications, or (7) apply specific thinking frameworks. Triggered by phrases like 'analyze this article,' 'help me understand,' 'deep dive into,' 'extract insights from,' 'use [framework name],' or when users provide URLs/long-form content for analysis.
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When the user wants to design or optimize the funnel that takes web visitors into installing and onboarding the app — including smart app banners, web-to-app deep links, deferred deep links, web onboarding (Stripe-paid web flow before app install), QR codes, "open in app" CTAs, and the trade-off between paying on web vs in-app. Use when the user mentions "web to app", "smart app banner", "Stripe before app", "web paywall before install", "Branch web SDK", "web funnel for app", "AppsFlyer OneLink web", "Universal Links", "App Links", "QR code to app", "open in app", "deferred deep link from web", or "should I sell on web first then push to app". For pure in-app onboarding, see onboarding-optimization. For deep link infra, see attribution-setup.
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Answers questions about Deep Code CLI itself — including features, configuration options, slash commands, Skills, MCP integration, permissions, notifications, session persistence, and troubleshooting. Use this when users ask how to configure or use Deep Code, how to set up an MCP server, configure notifications (such as Slack/Feishu), manage permissions, view available skills, understand slash commands, configure thinking mode, etc.
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Deepgram speech AI: transcribe audio to text and synthesize speech (TTS). Trigger phrases: deepgram, transcribe audio, speech to text, STT, deepgram tts.
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INVOKE THIS SKILL when building, testing, or deploying Managed Deep Agents in LangSmith. Walks a user through their first agent end to end — interviewing them about what they want to build, mapping it onto what MDA can actually do, then scaffolding and deploying it. Covers the file-based project layout; define_deep_agent / defineDeepAgent; instructions, skills, memory, identity, tools, MCP servers, connections, middleware, sandboxes, schedules, channels, and evals; the mda CLI; GitHub deployments; and Context Hub.
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Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.
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When you want multi-source, multi-step research on a topic — competitor research before a sales call, market research for a new business idea, positioning angles, due diligence on a partnership or podcast guest, tech decision research (which DB, which auth), or any "I need to actually understand X." Combines web search, URL fetch, agent-browser, last30days (Reddit/X/YouTube/HN/web recency), memory, and Notion. Outputs a structured brief with citations, contradictions, gaps, and recommended next steps. Archives every research run to ~/.config/makerskills/deep-research/archive/ so past work is searchable. Triggers on "/deep-research," "research X," "investigate X," "do a deep dive on X," "look into X," "what's actually happening with X," "due diligence on X," "validate this market." Differs from a one-shot web search: this is multi-pass with verification.
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Think and work like an expert Deep Learning Scientist. Use when a task calls for Deep Learning Scientist judgment. Reasons from CNN/Transformer inductive bias, Li et al. loss landscapes, grokking/mode connectivity, and Kaplan/Chinchilla scaling (~20 tokens/param); designs ResNet/ViT/DiT/MoE/FlashAttention stacks with FLOPs-matched ablations; trains AdamW+cosine/WSD via Megatron-FSDP/DeepSpeed; evaluates FID/MMLU-Pro/MMLU-CF with lm-eval decontamination and Pineau/NeurIPS reproducibility checklists.
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Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.
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