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Design valid marketing experiments with hypotheses, primary metrics, guardrails, sample/traffic assumptions, implementation QA and decision rules.

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Use when the user asks to "design an A/B test", "set up a creative/landing test", "run an incrementality test", or "is this result statistically and practically material?"; produces a hypothesis, variant matrix, sample-size/duration/power plan, and a documented effect/uncertainty read from own exported results. It applies only a precommitted owner-approved action rule; the statistical helper never chooses a business action. Not for producing variants — use ad-creative-builder; not for reading back one shipped change — use paid-measurement-loop. 广告AB测试设计/实验设计/显著性判定/增效测试

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Developer marketing and developer relations for B2B SaaS with technical audiences. Use this skill when the buyer or user is a developer: documentation as a marketing surface, quickstarts and time-to-first-call, SDKs and sample apps, developer community and DevRel programs, open-source strategy, and technical content that survives engineer scrutiny. Also triggers on: developer marketing, DevRel, developer relations, developer experience, DX, docs, documentation, quickstart, SDK, API marketing, open source strategy, developer community, technical content, dev audience, hacker news, engineering blog.

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Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.

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Systematic strategic planning framework for philosophy and interdisciplinary academic papers targeting preprint platforms (PhilArchive, arXiv, PhilSci-Archive). Use when users want to: (1) plan a paper on a specific topic, (2) identify research gaps and assess originality, (3) develop optimized paper outlines, (4) prepare for preprint submission, or (5) understand platform requirements and writing standards. Triggered by phrases like 'plan a paper on,' 'help me design a paper about,' 'identify research gaps in,' 'is this idea original,' or when users need structured research planning. The skill guides through three phases: Platform Analysis (identifying target venue and studying sample papers), Theoretical Framework (AI-driven literature search and gap identification), and Outline Optimization (structured design with reviewer-perspective self-assessment). Each phase includes quality evaluation standards and validation checkpoints.

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Generate read-only MongoDB queries (find) or aggregation pipelines using natural language, with collection schema context and sample documents. Use this skill whenever the user asks to write, create, or generate MongoDB queries, wants to filter/query/aggregate data in MongoDB, asks "how do I query...", needs help with query syntax, or discusses finding/filtering/grouping MongoDB documents. Also use for translating SQL-like requests to MongoDB syntax. Does NOT handle Atlas Search ($search operator), vector/semantic search ($vectorSearch operator), fuzzy matching, autocomplete indexes, or relevance scoring - use search-and-ai for those. Does NOT analyze or optimize existing queries - use mongodb-query-optimizer for that. Does NOT handle aggregation pipelines that involve write operations. Requires MongoDB MCP server.

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Microsoft docs lookup, code samples, and SDK reference for Azure, .NET, Microsoft 365, Windows, and Power Platform via Microsoft Learn MCP. Use for API reference or official MS documentation retrieval.

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Animation, morphing, and shader best practices for Liquid Glass and SwiftUI motion on iOS 26+/macOS 26+ through iOS 27. Use when animating glass or building UI motion: glassEffectID, @Namespace morphing, GlassEffectContainer spacing, glassEffectUnion, glassEffectTransition (.matchedGeometry/.materialize), withAnimation, springs, UnitCurve, PhaseAnimator, KeyframeAnimator, @Animatable, matchedTransitionSource, navigationTransition zoom, scrollTransition, visualEffect, Metal shaders (colorEffect, distortionEffect, layerEffect, [[stitchable]]), accessibilityReduceMotion gating, Instruments/xctrace profiling of hangs and animation hitches. Also fires on symptoms: glass morph not animating, view pops in instead of morphing, glass fades instead of materializing, morph flickers with Reduce Motion, menu glass morphs as a rectangle, animation runs on insert but not removal, PhaseAnimator loops forever or fires once, shader shows clipped edges (maxSampleOffset), animation hitches or main-thread hangs while scrolling glass chrome. For static glass, availability gating, toolbars, UIKit/AppKit glass, or accessibility of the material itself use the liquid-glass skill first.

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MCP server for Apple Developer Documentation. Search iOS/macOS/SwiftUI/UIKit docs, WWDC videos with transcripts, sample code, and framework APIs. Use when you need to look up Apple APIs, check platform compatibility, find WWDC sessions, or browse framework symbols. Install the MCP server first, then use its tools.

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Busabase App-in-Skill dashboard over a fixed, deterministic mock user-behavior funnel dataset (browse → search → compare → booking attempt/abandon → complete) for a generic consumer booking product. Use when the user invokes $kelly-behavior-predict or /kelly-behavior-predict, wants to review funnel drop-off, per-segment predicted next actions, or backtest a rule-based "predicted next action" heuristic against a mock historical sample. Fully deterministic mock data and a hand-recomputable rule — never a real ML/LLM model, never a live system.

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Detects AI-generated deepfake audio used in voice phishing (vishing) attacks by extracting spectral features (MFCC, spectral centroid, spectral contrast, zero-crossing rate) and classifying samples with machine learning models. Supports batch analysis of audio files, generates confidence scores, and produces forensic reports. Activates for requests involving deepfake voice detection, vishing investigation, AI-generated speech analysis, voice cloning detection, or audio authenticity verification.

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Detect sandbox evasion techniques in malware samples by analyzing timing checks, VM artifact queries, user interaction detection, and sleep inflation patterns from Cuckoo/AnyRun behavioral reports

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Analyzes bootkit and advanced rootkit malware that infects the Master Boot Record (MBR), Volume Boot Record (VBR), or UEFI firmware to gain persistence below the operating system. Covers boot sector analysis, UEFI module inspection, and anti-rootkit detection techniques. Activates for requests involving bootkit analysis, MBR malware investigation, UEFI persistence analysis, or pre-OS malware detection.

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Analyzes malicious Linux ELF (Executable and Linkable Format) binaries including botnets, cryptominers, ransomware, and rootkits targeting Linux servers, containers, and cloud infrastructure. Covers static analysis, dynamic tracing, and reverse engineering of x86_64 and ARM ELF samples. Activates for requests involving Linux malware analysis, ELF binary investigation, Linux server compromise assessment, or container malware analysis.

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Executes malware samples in Cuckoo Sandbox to observe runtime behavior including process creation, file system modifications, registry changes, network communications, and API calls. Generates comprehensive behavioral reports for malware classification and IOC extraction. Activates for requests involving dynamic malware analysis, sandbox detonation, behavioral analysis, or automated malware execution.

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Perform static analysis of Android APK malware samples using apktool for decompilation, jadx for Java source recovery, and androguard for permission analysis, manifest inspection, and suspicious API call detection.

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Focused Signals scout for PostHog projects running A/B experiments. Watches running experiments for validity threats (sample ratio mismatch, multi-variant contamination, exposure stalls, mid-run flag mutations) and lifecycle drift (zombie experiments running long past their useful life, decided-but-still-running experiments, ended experiments whose flags still serve multiple variants). Emits findings only when they clear the confidence bar; otherwise writes durable memory and closes out empty. Self-contained peer in the signals-scout-* fleet — no dependencies on other skills.

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Investigates a single PostHog error tracking issue end-to-end. Use when the user provides an issue ID or pastes an issue URL (`/error_tracking/<id>`) and wants to understand the error — who it affects, what triggers it, when it started, whether it correlates with a release, browser, OS, or feature flag, and what the next step should be. Pulls aggregated metrics, sample exception events, segment breakdowns, linked replays, and synthesizes a hypothesis-grade summary in one pass.

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Diagnoses bias, anomalies, and strange-looking results on a specific PostHog experiment. Covers empty / 0-exposure experiments, sample ratio mismatch, identity fragmentation, multi-variant exposure, uneven-split exclusion bias, significance traps (peeking, A/A, Bayesian vs Frequentist), PostHog-vs-SQL discrepancies, and surprises after mid-run edits. Symptom-driven dispatch to the right diagnostic. TRIGGER when: user asks 'is my experiment biased?' or 'why 0 exposures?', references the bias banner, says a variant looks strange / wrong / off, sees significance flipping, notices PostHog numbers disagreeing with their SQL, sees an A/A test showing significance, or reports surprises after mid-run edits. DO NOT TRIGGER when: creating a new experiment (use creating-experiments), only configuring rollout (use configuring-experiment-rollout) or metrics (use configuring-experiment-analytics), or only asking lifecycle questions (use managing-experiment-lifecycle).

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Plot per-group distributions of continuous data using boxplots, violins, beeswarms, quasirandom jitter, and raincloud plots with sample-size honesty (Weissgerber 2015), KDE-bandwidth awareness, and N-aware encoding choices. Use when comparing distributions across a small number of groups — expression per cluster, biomarker per arm, scores per condition — and the bar-of-mean default is misleading.

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Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the experimental-vs-observational unit distinction and pseudoreplication (Hurlbert 1984; Lazic 2018), randomization mechanics (complete, restricted, stratified, rerandomization, run-order), blocking layouts (randomized complete block, Latin square, incomplete block), factorial designs and interactions, and the split-plot/nested error strata hidden inside multi-batch genomics. Use when deciding the experimental unit and what counts as a replicate, planning randomization and run order, choosing a blocked/factorial/split-plot/nested layout, avoiding pseudoreplication in cell-culture or animal studies, or specifying the random-effects structure of the analysis model. For assigning samples to sequencing batches/lanes/plates and batch-effect correction see experimental-design/batch-design; for regulated clinical-trial randomization see clinical-biostatistics.

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Strategic clinical trial design feasibility assessment. Analyzes 6 dimensions (endpoint, population, comparator, effect size, duration, regulatory pathway) using precedent trials and FDA guidance. Produces enrollment projections, endpoint recommendations, and approval-pathway analysis. Use for trial-protocol design, power/sample-size estimation, comparator selection, and FDA submission strategy. Driven by precedent-based reasoning rather than first-principles math.

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Mendelian randomization (MR) causal inference — does an exposure, risk factor, or biomarker CAUSALLY affect a disease/outcome, using genetic variants as instrumental variables (IEU OpenGWAS / EpiGraphDB MR-EvE). Use this whenever the user asks if X causes Y, whether an observational association is actually causal or just correlation, if a biomarker/trait is a causal risk factor, wants to triangulate epidemiology against genetic evidence, or mentions Mendelian randomization, instrumental-variable analysis, two-sample MR, or genetic causal evidence — even if they never say "MR" (e.g. "is LDL cholesterol actually causal for heart disease?", "does BMI cause type 2 diabetes or just correlate?", "is CRP a causal driver of stroke?"). Covers trait-label resolution, MR effect direction/magnitude, instrument quality (MOE score), method agreement (IVW vs MR-Egger vs weighted median), bidirectional MR for reverse causation, and distinguishing causation from genetic correlation. Not for plain GWAS association lookups (use the GWAS skills) or fitting your own instruments from raw summary statistics.

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End-to-end bulk time-course analysis from an expression matrix to temporal gene modules and per-cluster pathway enrichment. Orchestrates temporal DE (limma splines or DESeq2 LRT), Mfuzz/tslearn soft clustering of expression-profile shapes, GAM trajectory fitting, per-cluster GO enrichment against a temporal-gene background, and an OPTIONAL circadian rhythm-detection branch (MetaCycle/CosinorPy) that runs only when the design covers >=2 full cycles with >=6-8 evenly spaced samples per cycle. Use when analyzing a bulk time-series expression experiment from any omics platform and deciding limma-splines vs DESeq2-LRT for temporal DE, soft vs hard clustering, whether the sampling design even licenses rhythm detection, and which background to use for enrichment. Not for single-cell pseudotime (see temporal-genomics/trajectory-modeling for the bulk-vs-pseudotime boundary) or unknown-period discovery (see temporal-genomics/periodicity-detection).

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