Detect, date, and contextualize whole-genome duplication (WGD / paleopolyploidy) events using wgd v2 (Chen & Zwaenepoel 2024), KsRates (Sensalari 2022 substitution-rate-corrected Ks dating), DupGen_finder (Qiao 2019), MAPS (Li 2018 phylogenomic), POInT (Conant 2008 ordered-block), SLEDGe (2024 ML-based), Whale.jl (Bayesian DTL+WGD), and synteny-anchored paranome construction. Use when identifying ancient polyploidy from Ks distributions and synteny block analysis, positioning WGD events relative to speciation, distinguishing tandem from segmental from WGD duplications, dating the 2R/3R vertebrate / fish / salmonid WGDs, building paranome and Ks-age mixture models, applying KsRates substitution-rate correction across lineages, or testing alternative biased-fractionation / dosage-balance models post-WGD.
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peacezha/HPClaw☆ 32026年10月11日 更新
Visualize copy number profiles, segments, allele-specific tracks, and cohort patterns from CNVkit, GATK, ASCAT, FACETS, Sequenza, and other callers. Covers genome-wide and per-chromosome log2 scatter plots, B-allele-frequency/minor-allele-fraction tracks, ideograms, cohort heatmaps, circos views, and caller-native plots. Use when creating publication CNV figures, choosing which plot answers a given question, diagnosing a wrong diploid baseline visually, displaying loss of heterozygosity, or deciding what depth-only plots cannot reveal.
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peacezha/HPClaw☆ 32026年10月11日 更新
Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.
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peacezha/HPClaw☆ 32026年10月11日 更新
Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.
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peacezha/HPClaw☆ 32026年10月11日 更新
Creates sashimi-style plots showing RNA-seq read coverage and splice junction counts using ggsashimi (general-purpose, condition-grouped overlays), rmats2sashimiplot (rMATS-output-aware), MAJIQ-VOILA (LSV posteriors interactive HTML), leafviz (leafcutter clusters Shiny), Jutils (tool-agnostic heatmaps and sashimi for rMATS/leafcutter/SUPPA2/MAJIQ output), or pyGenomeTracks (multi-track publication figures). Tool choice depends on the upstream differential-splicing tool's output format and the publication vs interactive use case. Use when visualizing specific splicing events, validating differential splicing calls, or producing publication-quality figures.
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peacezha/HPClaw☆ 32026年10月11日 更新
Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.
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peacezha/HPClaw☆ 32026年10月11日 更新
Strategic analyst that maps competitive landscapes, identifies white space opportunities, and provides positioning recommendations. Use when users need competitive analysis, market positioning strategy, differentiation tactics, or "how do I stand out?" guidance across any domain (portfolios, products, services). NOT for market size estimation or financial forecasting.
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curiositech/port-daddy☆ 32026年10月19日 更新
Render mathematically-faithful Turkish marbling (Ebru) and paper-marbling with closed-form coordinate-deformation maps — a drop is a radial outward push, a comb/tine is a decaying shear, all composed as homeomorphisms over colored region boundaries. No fluid solver, runs 60fps on a 2D canvas. Use when building a marbling/Ebru toy or generative-art renderer, implementing drop/comb/wave/swirl deformations, scripting traditional patterns (Battal, Gel-Git, Şal, Bülbül Yuvası), keeping combed edges crisp via adaptive resampling, modeling ox-gall shouldering for crisp ring-in-ring drops, or exporting high-DPI marbled prints. NOT for real fluid / Navier-Stokes simulation, metaball / alpha-blended "smoke" blob effects, raster image-processing filters, or non-marbling generative art.
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curiositech/port-daddy☆ 32026年10月19日 更新
Construct a finite oriented simplicial or cellular cochain model and compute its stated linear invariants when coefficient spaces, maps, metrics, and observations are explicit. Use for scoped Hodge, rank, or residual calculations; not for attributing agent intent or authorizing effects. NOT for attributing intent, identifying a liar, or authorizing external effects.
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curiositech/port-daddy☆ 32026年10月19日 更新
Analyze existing XML sitemaps or generate new ones with industry templates. Validates format, URLs, and structure. Use when user says "sitemap", "generate sitemap", "sitemap issues", or "XML sitemap".
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balsm-health/website☆ 32026年10月18日 更新
Google SEO APIs: Search Console (Search Analytics, URL Inspection, Sitemaps), PageSpeed Insights v5, CrUX field data with 25-week history, Indexing API v3, and GA4 organic traffic. Provides real Google field data for Core Web Vitals, indexation status, search performance, and organic traffic trends. Use when user says "search console", "GSC", "PageSpeed", "CrUX", "field data", "indexing API", "GA4 organic", "URL inspection", or "real CWV data".
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balsm-health/website☆ 32026年10月18日 更新
Remotion Map animation knowledge
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remotion-dev/cursor-plugin☆ 32026年10月20日 更新
Remotion Map animation knowledge
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remotion-dev/agent-plugin☆ 32026年9月1日 更新
Use when adding or updating Spark AI provider models or their compact and preflight metrics, especially baidu-oneapi, Grok, Claude, GPT, DeepSeek, OneAPI, context windows, output budgets, prices, thinking maps, or transports.
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zendev-lab/cogfold☆ 22026年10月19日 更新
Runs the test-first build loop (spec, plan, thin slices, failing test first, verify, commit) for a Godot 4 game in GDScript or C# first; in a TypeScript, Python or other repo when test-first, slices or a reproduce-first fix is asked for. Trigger to build or add a game feature, mechanic, stat, system or milestone, even when told to test later; to turn a spec or grill record into slices; to fix a game bug from a reproduction, one hypothesis at a time; on "write the test first", "what's the next slice", "is this slice done" or "is this milestone ready to exit"; or say slicesmith (spec, plan, slice, fix, exit). Run proof and gate rulings are godotsmith's; diff review a review tool's; repo maps researchscribe's; art pixelsmith's; audio soundsmith's; interviews grillwright's; fan-out dispatchwright's.
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revenantworks/claude-skills☆ 22026年10月20日 更新
Audits what Claude may do (permission rules, hooks, MCP scope, an agent's grants) and maps what it reaches on disk. Trigger on audit my permissions, why was this allowed, what stalls a routine, swap an allow for a deny, is this hook safe, gate my git pushes, a guard hook or call cap, PowerShell twins of Bash denies, where a rule should live, what is eating my disk, where has Claude been, config drift from a repo copy, skills loading twice; or say gatewarden (audit, harden, explain, scan, hooks, capreview, layout, map, footprint, drift, loads, status, refresh). Installs are trustwarden's; tokens keywarden's; secrets shieldwarden's; standing config rigwright's; agent design agentwright's.
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revenantworks/claude-skills☆ 22026年10月20日 更新
Decides where a standing rule lives and builds the config Claude reads before work — CLAUDE.md, AGENTS.md, Project instructions and knowledge files, profile preferences, .claude/rules and agents, hooks, .mcp.json. Trigger on 'where should this rule live', 'set up a Claude Project', 'write or trim my CLAUDE.md', 'my rules get ignored', 'audit my setup for bloat or stale status', 'cut my CLAUDE.md token cost', 'add what we learned to CLAUDE.md', or rigwright (place, build, audit, learn, slim, refresh). Permissions, hook safety and config maps are gatewarden's; skills, skillwright's; unattended work, agentwright's; a block's wording, promptwright's.
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revenantworks/claude-skills☆ 22026年10月20日 更新
2D game development principles. Sprites, tilemaps, physics, camera.
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MikeCheng1208/BattleTree☆ 22026年7月22日 更新
Analyze market conditions, geographic opportunities, pricing, consumer behavior, and product validation across Google Maps, Facebook, Instagram, Booking.com, and TripAdvisor.
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MMEHDI0606/ai-agent-foundation-template☆ 22026年5月21日 更新
Analyze competitor strategies, content, pricing, ads, and market positioning across Google Maps, Booking.com, Facebook, Instagram, YouTube, and TikTok.
中文简介正在准备中。当前显示原文说明。
MMEHDI0606/ai-agent-foundation-template☆ 22026年5月21日 更新
Universal AI-powered web scraper for any platform. Scrape data from Instagram, Facebook, TikTok, YouTube, LinkedIn, X/Twitter, Google Maps, Google Search, Google Trends, Reddit, Airbnb, Yelp, and 15+ more platforms. Use for lead generation, brand monitoring, competitor analysis, influencer discovery, trend research, content analytics, audience analysis, review analysis, SEO intelligence, recruitment, or any data extraction task.
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aAAaqwq/openclaw-team☆ 22026年6月18日 更新
Analyze competitor strategies, content, pricing, ads, and market positioning across Google Maps, Booking.com, Facebook, Instagram, YouTube, and TikTok.
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aAAaqwq/openclaw-team☆ 22026年6月18日 更新
Framework-directable information security risk assessment. Identifies threats, evaluates likelihood/impact via a 3x3 matrix, maps findings to any compliance framework, and recommends risk treatment options with prioritization guidance.
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aAAaqwq/openclaw-team☆ 22026年6月18日 更新
Scan global talent markets via GitHub/Arxiv/LinkedIn APIs, build talent heatmaps with salary benchmarks, identify Tier S/A/B/C candidates. Use when: quarterly talent scanning, critical role hiring, competitive intelligence on talent pools. Includes real API integrations and data pipeline.
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aAAaqwq/openclaw-team☆ 22026年6月18日 更新