Comparison of the four guideline-approved psychotherapy approaches in Germany: Cognitive Behavioral Therapy, Psychodynamic Therapy, Psychoanalysis, Systemic Therapy — Orientation guide.
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Comparison of the four guideline-approved psychotherapy approaches in Germany: Cognitive Behavioral Therapy, Psychodynamic Therapy, Psychoanalysis, Systemic Therapy — Orientation guide.
中文简介正在准备中。当前显示原文说明。
Nominates and assesses CRISPR off-target sites genome-wide. Enumerates candidate sites by mismatch and bulge tolerance with Cas-OFFinder/CRISPRitz, ranks them with the published CFD score (SpCas9-only, relative ranker) or MIT/CRISTA/energy models, runs variant-aware screening against gnomAD/individual genomes (CRISPRme), and frames the empirical genome-wide discovery assays (GUIDE-seq, CIRCLE-seq, CHANGE-seq, DISCOVER-seq, Digenome-seq) and high-fidelity nuclease choice (HiFi Cas9, Sniper-Cas9, eSpCas9, SpCas9-HF1). Use when assessing guide RNA specificity, choosing among candidate guides, screening a therapeutic guide against population variation, or planning empirical off-target validation. Distinguishes predicted vs detected vs validated. On-target activity scoring and deaminase (Cas-independent) base/prime-editor off-targets are separate skills.
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Nominates and assesses CRISPR off-target sites genome-wide. Enumerates candidate sites by mismatch and bulge tolerance with Cas-OFFinder/CRISPRitz, ranks them with the published CFD score (SpCas9-only, relative ranker) or MIT/CRISTA/energy models, runs variant-aware screening against gnomAD/individual genomes (CRISPRme), and frames the empirical genome-wide discovery assays (GUIDE-seq, CIRCLE-seq, CHANGE-seq, DISCOVER-seq, Digenome-seq) and high-fidelity nuclease choice (HiFi Cas9, Sniper-Cas9, eSpCas9, SpCas9-HF1). Use when assessing guide RNA specificity, choosing among candidate guides, screening a therapeutic guide against population variation, or planning empirical off-target validation. Distinguishes predicted vs detected vs validated. On-target activity scoring and deaminase (Cas-independent) base/prime-editor off-targets are separate skills.
中文简介正在准备中。当前显示原文说明。
为人工测试OpenClaw候选版本准备隔离的OCM副本或经批准的现有Gateway环境,指导测试、整理反馈,并协助在公开报告前检查内容。
使用REA分析已发布的应用、二进制文件、软件包和固件,解释功能并比较版本差异。结合反编译与运行时观察,区分证据、推断和未知事项。
将笔记、访谈转录和研究资料整理为博客文章、指南、教程或通讯,参照既有文风和品牌要求安排结构,并用所提供的材料支撑事实性主张。
根据提供的写作示例或品牌风格撰写文章、指南和简报,将笔记、转录文本与研究资料整理成文,也可检查现有稿件的结构、论据及风格一致性。
将外部服务的初始设置和凭据登记整理为供人逐步操作的交互式bash脚本,包含操作指引、输入值保存、剩余阶段提示及各阶段确认。
将服务概况、告警及初步应对、监控链接、可复制的操作命令、应急值班表和故障响应清单整理为单页HTML运维手册,便于集中查阅操作说明。
用于创建、填写和重新排版符合品牌风格的PDF、电子指南及报告。通过共用设计设置和15种封面样式,统一文档外观,并兼顾封面与正文的呈现。
将Anthropic官方品牌配色与字体排版规范应用于作品,统一颜色与文字的视觉呈现,也可作为制定自有品牌规范时的参考。
Generate videos from structured prompts describing subjects, visual style, camera work, and other scene details. The workflow creates English JSON prompts and runs a Python script, with optional reference images to guide the result.
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Review blog posts, landing pages, and guides for readability. Estimate reading difficulty, identify long sentences and jargon, and simplify wording and paragraph structure so broad audiences can follow the content more easily.
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Draft and revise OpenSpec user documentation using its house style. Organize task guides and reference pages so readers can quickly find answers, commands, file paths, and troubleshooting details, while identifying claims that remain unchecked.
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Prepare for four Claude certification tracks through guided lessons, practical exercises, quizzes, and mock exams. The tutor checks understanding and learner-created work, records progress, and uses assessment results to guide review.
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Create and revise fixed-layout PDFs such as reports, guides, and printable documents. The skill also covers reading, merging, splitting, cropping, and filling existing PDFs, with rendering checks and visual review before delivery.
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Use 高性价比人生指南 to examine practical life decisions, from choosing an action to checking benefits or legality. Relevant entries are retrieved first, then ranked by costs, benefit size, and evidence strength, with section and entry references.
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Route Remotion tasks to the relevant specialist guides, from creating videos and projects to captions, maps, and rendering. It also guides Studio preview setup, package upgrades, and troubleshooting when working inside Codex.
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Initialize a new MemPalace for AI memory through a guided setup process. The skill retrieves setup instructions for a configuration that uses ChromaDB as its data storage backend and follows the returned steps.
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Guides agents in choosing Cherry Studio tools for research, document conversion, memory, notifications, and other tasks. It explains when to use app tools or local runtimes, with checks for availability, configuration, and approval.
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Organize API documentation work from endpoint discovery to OpenAPI specifications, developer guides, and tested code examples. The workflow also covers interactive documentation, documentation sites, and maintenance, helping select the phases and supporting skills needed for a task.
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Guide AI coding work toward simple implementations, focused edits, and explicit assumptions. Use it when writing, reviewing, or refactoring code to keep changes tied to the request and define success through tests or other concrete checks.
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Guide Angular development, code review, and refactoring with prioritized performance rules. Review rendering efficiency, loading time, and bundle size—the amount of code delivered to browsers—alongside data fetching and server-rendered page setup.
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Write or update repository and product documentation, including README files, user guides, API documentation, architecture notes, and migration instructions. Identify the audience, improve existing documents where possible, and verify commands and paths while flagging unknown details.
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