Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles, applicability domain (kNN, leverage, conformal prediction, Mahalanobis), scaffold-balanced splits, ensemble uncertainty, calibration (Platt, isotonic), feature importance (SHAP, atomic attribution), and prospective validation. Use when building target-specific predictive models from in-house bioassay data, ADMET endpoints, or selectivity profiles.
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peacezha/HPClaw☆ 32026年10月11日 更新
Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass cohort-style alignment, junction saturation curves and discovery plateau detection, novel-vs-known junction ratio diagnostics, junction-overhang distribution, splice-site strength scoring (MaxEntScan intrinsic + SpliceAI context-aware), strandedness verification, GENCODE basic vs comprehensive choice, and rRNA contamination screening. Splicing analysis is more demanding than DGE on read length, depth, library prep, alignment strategy, and annotation choice — failures silently bias PSI estimates and inflate novel-junction false positives. Use when evaluating data suitability for splicing analysis, troubleshooting low event detection, or designing sequencing experiments where AS is a primary endpoint.
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peacezha/HPClaw☆ 32026年10月11日 更新
Expert API designer for REST, GraphQL, gRPC architectures. Activate on: API design, REST API, GraphQL schema, gRPC service, OpenAPI, Swagger, API versioning, endpoint design, rate limiting, OAuth flow. NOT for: database schema (use data-pipeline-engineer), frontend consumption (use web-design-expert), deployment (use devops-automator).
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curiositech/port-daddy☆ 32026年10月19日 更新
Doctrine for adding a capability INTO a live, existing feature to a world-class bar. Use on 'add X to Y', 'extend Y to support X', a new option, button, setting, endpoint, or tool for Y, or a sub-feature spec to implement. NOT for whole-feature audits or overhauls (use feature-deep-dive).
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armanisadeghi/ai-matrx☆ 32026年10月21日 更新
A live demo or admin page shipped with every feature whose results the user would otherwise not see. Use when building or extending a server-side capability, service, registry, or pipeline, or adding a backend endpoint or feature with no UI, whose output only shows in logs, the DB, or an agent run, or when the user says there's no way to see it or asks 'how do I test this'.
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armanisadeghi/ai-matrx☆ 32026年10月21日 更新
Convex backend specialist. Use this agent for any code inside a `convex/` directory — function definitions, schemas, indexes, queries, mutations, actions, HTTP endpoints, cron jobs, file storage, auth wiring, and component installation. Knows the object-form function syntax, validator patterns, resource limits, and component ecosystem that generic Claude routinely gets wrong.
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waynesutton/waynesutton-ai☆ 22026年9月8日 更新
Create Convex queries, mutations, and actions with proper validation, authentication, and error handling. Use when implementing new API endpoints.
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waynesutton/waynesutton-ai☆ 22026年9月8日 更新
Generates ADR Action classes for PHP 8.5. Creates single-responsibility HTTP endpoint handlers with PSR-7 support. Includes unit tests.
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MikeCheng1208/BattleTree☆ 22026年7月22日 更新
Generates API documentation for PHP projects. Creates endpoint documentation with parameters, responses, and examples.
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MikeCheng1208/BattleTree☆ 22026年7月22日 更新
Implement REST APIs in ABP Framework with AppServices, DTOs, pagination, filtering, and authorization. Use when building API endpoints for ABP applications.
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MikeCheng1208/BattleTree☆ 22026年7月22日 更新
Agent-to-Agent (A2A) server configuration patterns for HTTP, STDIO, SSE, and WebSocket transports. Use when building A2A servers, configuring MCP transports, setting up server endpoints, or when user mentions A2A configuration, server transport, MCP server setup, or agent communication protocols.
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MikeCheng1208/BattleTree☆ 22026年7月22日 更新
Use this skill when adding authentication, handling user input, working with secrets, creating API endpoints, or implementing payment/sensitive features. Provides comprehensive security checklist and patterns.
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sayasaya8039/ZWG_Terminal☆ 22026年6月8日 更新
Azure Monitor Ingestion SDK for Java. Send custom logs to Azure Monitor via Data Collection Rules (DCR) and Data Collection Endpoints (DCE).
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MMEHDI0606/ai-agent-foundation-template☆ 22026年5月21日 更新
Provide comprehensive techniques for penetration testing AWS cloud environments. Covers IAM enumeration, privilege escalation, SSRF to metadata endpoint, S3 bucket exploitation, Lambda code extraction, and persistence techniques for red team operations.
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MMEHDI0606/ai-agent-foundation-template☆ 22026年5月21日 更新
Generate comprehensive, developer-friendly API documentation from code, including endpoints, parameters, examples, and best practices
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MMEHDI0606/ai-agent-foundation-template☆ 22026年5月21日 更新
Lists all inference providers offered during NemoClaw onboarding. Use when explaining which providers are available, what the onboard wizard presents, or how inference routing works. Trigger keywords - nemoclaw inference options, nemoclaw onboarding providers, nemoclaw inference routing, switch nemoclaw inference model, change inference runtime, nemoclaw local inference, ollama nemoclaw, vllm nemoclaw, local model server, openai compatible endpoint.
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composio-community/nemoclaw-composio☆ 22026年4月30日 更新
Expert in integrating third-party APIs with proper authentication, error handling, rate limiting, and retry logic. Use when integrating REST APIs, GraphQL endpoints, webhooks, or external services. Specializes in OAuth flows, API key management, request/response transformation, and building robust API clients.
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David-Li0406/meta-skill-evloving☆ 22026年7月14日 更新
Interactive onboarding tour for the context-matic MCP server. Walks the user through what the server does, shows all available APIs, lets them pick one to explore, explains it in their project language, demonstrates model_search and endpoint_search live, and ends with a menu of things the user can ask the agent to do. USE FOR: first-time setup; "what can this MCP do?"; "show me the available APIs"; "onboard me"; "how do I use the context-matic server"; "give me a tour". DO NOT USE FOR: actually integrating an API end-to-end (use integrate-context-matic instead).
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jcasnellie69/homelab-config☆ 22026年10月16日 更新
Discovers and integrates third-party APIs using the context-matic MCP server. Uses `fetch_api` to find available API SDKs, `ask` for integration guidance, `model_search` and `endpoint_search` for SDK details. Use when the user asks to integrate a third-party API, add an API client, implement features with an external API, or work with any third-party API or SDK.
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jcasnellie69/homelab-config☆ 22026年10月16日 更新
Manage Azure DevOps resources via CLI including projects, repos, pipelines, builds, pull requests, work items, artifacts, and service endpoints. Use when working with Azure DevOps, az commands, devops automation, CI/CD, or when user mentions Azure DevOps CLI.
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jcasnellie69/homelab-config☆ 22026年10月16日 更新
Create ASP.NET Minimal API endpoints with proper OpenAPI documentation
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jcasnellie69/homelab-config☆ 22026年10月16日 更新
Install, configure, and manage 1-SEC — an open-source, all-in-one cybersecurity platform (16 modules, single binary) on Linux servers and VPS instances. Use when the user asks to secure a server, install security monitoring, set up intrusion detection, harden a VPS, protect an AI agent host, or deploy endpoint defense. Covers installation, setup, enforcement presets, module configuration, alert management, and ongoing security operations.
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Lord1Egypt/awesome-skill-forge☆ 22026年6月10日 更新
Complete guide for ASP.NET Core Web API integration testing. Use when performing integration testing on Web API endpoints or validating ProblemDetails error format. Covers WebApplicationFactory, IExceptionHandler, Testcontainers multi-container orchestration, Flurl URL construction, and AwesomeAssertions HTTP validation. Keywords: webapi integration testing, WebApplicationFactory, asp.net core integration test, webapi integration test, IExceptionHandler, ProblemDetails, ValidationProblemDetails, AwesomeAssertions, Flurl, Respawn, Be201Created, Be400BadRequest, multi-container testing, Collection Fixture, global exception handling
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rudironsoni/Synaxis☆ 22026年3月17日 更新
Extend dev-software-engineer with .NET/C# backend specialization for Clean Architecture, CQRS, EF Core, and production-ready API practices. Use when tasks involve ASP.NET endpoints, handlers, services, dependency injection, MediatR, migrations, or backend performance/resilience.
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ThiagoGuislotti/copilot-instructions☆ 22026年6月29日 更新