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Build an automated pipeline to defang indicators of compromise (URLs, IPs, domains, emails) for safe sharing and distribute them in STIX format through TAXII feeds and threat intelligence platforms.
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Designs and documents structured incident response playbooks that define step-by-step procedures for specific incident types aligned with NIST SP 800-61r3 and SANS PICERL frameworks. Covers playbook structure, decision trees, escalation criteria, RACI matrices, and integration with SOAR platforms. Activates for requests involving IR playbook creation, incident response procedure documentation, response runbook development, or SOAR playbook design.
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Performs runtime mobile security exploration of iOS applications using Objection, a Frida-powered toolkit that enables security testers to interact with app internals without jailbreaking. Use when assessing iOS app security posture, bypassing client-side protections, dumping keychain items, inspecting filesystem storage, and evaluating runtime behavior. Activates for requests involving iOS security testing, Objection runtime analysis, Frida-based iOS assessment, or mobile runtime exploration.
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Performs Linux memory acquisition using LiME (Linux Memory Extractor) kernel module and analysis with Volatility 3 framework. Extracts process lists, network connections, bash history, loaded kernel modules, and injected code from Linux memory images. Use when performing incident response on compromised Linux systems.
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Analyzes DNS query logs to detect data exfiltration via DNS tunneling, DGA domain communication, and covert C2 channels using entropy analysis, query volume anomalies, and subdomain length detection in SIEM platforms. Use when SOC teams need to identify DNS-based threats that bypass traditional network security controls.
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Assists in writing high-quality content by conducting research, adding citations, improving hooks, iterating on outlines, and providing real-time feedback on each section. Transforms your writing process from solo effort to collaborative partnership.
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Transforms conversations and discussions into structured documentation pages in Notion. Captures insights, decisions, and knowledge from chat context, formats appropriately, and saves to wikis or databases with proper organization and linking for easy discovery.
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Converts Claude Code skills to Gemini CLI extensions and vice versa. Use when the user wants to make a skill cross-platform compatible, port a skill between platforms, or create a universal extension that works on both Claude Code and Gemini CLI.
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Comprehensive PDF manipulation toolkit for extracting text and tables, creating new PDFs, merging/splitting documents, and handling forms. When Claude needs to fill in a PDF form or programmatically process, generate, or analyze PDF documents at scale.
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Downloads videos from YouTube and other platforms for offline viewing, editing, or archival. Handles various formats and quality options.
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Use this skill whenever the user wants to do anything with PDF files. This includes reading or extracting text/tables from PDFs, combining or merging multiple PDFs into one, splitting PDFs apart, rotating pages, adding watermarks, creating new PDFs, filling PDF forms, encrypting/decrypting PDFs, extracting images, and OCR on scanned PDFs to make them searchable. If the user mentions a .pdf file or asks to produce one, use this skill.
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Use this skill whenever the user wants to do anything with PDF files. This includes reading or extracting text/tables from PDFs, combining or merging multiple PDFs into one, splitting PDFs apart, rotating pages, adding watermarks, creating new PDFs, filling PDF forms, encrypting/decrypting PDFs, extracting images, and OCR on scanned PDFs to make them searchable. If the user mentions a .pdf file or asks to produce one, use this skill.
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Help users debug PostHog Error Tracking stack-trace symbolication for any supported platform — JavaScript/TypeScript web, React Native (Hermes), Android (Proguard / R8), or iOS / macOS (dSYM). The PostHog symbol-set lookup flow is universal across platforms; build-tool and artifact details live in per-platform references (JavaScript is fleshed out, others come as we encounter them). Use when stack frames stay minified or obfuscated after symbols are uploaded, PostHog symbol sets show last_used but frames are not readable, chunk IDs or dSYM UUIDs do not match, "Token not found" appears, uploaded source maps / dSYMs / Proguard mappings look empty, or bundler / symbol-upload configuration needs troubleshooting.
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Performs time-to-event analysis for clinical trials including Cox proportional hazards regression with PH diagnostics, restricted mean survival time (RMST) under non-PH, competing risks via Fine-Gray vs cause-specific Cox, weighted log-rank and MaxCombo for non-proportional hazards, recurrent events (Andersen-Gill, PWP, WLW), and interval-censored data. Use when analyzing time-to-event endpoints (OS, PFS, DOR, TTR, TTNT) in oncology or other clinical trials.
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Performs logistic regression for clinical trial outcomes (binary, ordinal, multinomial) with marginal-vs-conditional estimand reporting per FDA 2023 covariate adjustment guidance, g-computation/standardisation for marginal effects, modified Poisson for RR, Brant test for proportional odds, Firth penalty for separation, and Hauck-Donner detection. Use when modeling binary or ordinal endpoints in confirmatory or exploratory clinical trials.
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Frequency-domain analysis — FFT, power spectral density (Welch/periodogram), spectrograms, wavelet transforms, and coherence. Use for any signal with periodic, quasi-periodic, or transient frequency content in physics data.
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Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.
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Evaluates LLMs across 100+ benchmarks from 18+ harnesses (MMLU, HumanEval, GSM8K, safety, VLM) with multi-backend execution. Use when needing scalable evaluation on local Docker, Slurm HPC, or cloud platforms. NVIDIA's enterprise-grade platform with container-first architecture for reproducible benchmarking.
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Automatically discover life science APIs online, create ToolUniverse tools, validate them, and prepare integration PRs. Performs gap analysis to identify missing tool categories, web searches for APIs, automated tool creation using devtu-create-tool patterns, validation with devtu-fix-tool, and git workflow management. Use when expanding ToolUniverse coverage, adding new API integrations, or systematically discovering scientific resources.
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Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda window scheduling, soft-core potentials, REST2 enhanced sampling, MBAR/BAR analysis, and cycle closure validation. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.
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Performs structure-based virtual screening using AutoDock Vina, SMINA, GNINA (CNN scoring), and DiffDock-L hybrid workflows with explicit choice rules across rigid vs flexible docking, cross-docking vs self-docking, binding-site detection (P2Rank, fpocket), receptor preparation (PDB2PQR, PROPKA), ligand preparation (meeko, OpenBabel), and ultralarge-library screening (ZINC22, Enamine REAL). Use when screening chemical libraries against a protein target to find candidate binders, ranking docking poses, or selecting a docking workflow for a specific scenario.
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Performs retrosynthetic planning using AiZynthFinder (MCTS, template-based), Chemformer (template-free transformer), ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, building-block availability (eMolecules, Enamine, Mcule), forward prediction validation (Molecular Transformer), and disconnection-aware multi-objective search (MO-MCTS). Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.
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Performs ML-based protein-ligand pose prediction and scoring using DiffDock-L (diffusion-based), Boltz-1 / Boltz-2 (foundation model with affinity), Chai-1, AlphaFold3 ligand, EquiBind, TANKBind, NeuralPLexer, and hybrid workflows (DiffDock pose + GNINA rescore + PoseBusters QC). Explicit handling of when ML beats classical docking, when classical beats ML, the PB-invalid pose problem, and rescoring as the standard production hybrid. Use when modern docking is needed: foundation-model ligand-pose prediction, AI rescoring of classical poses, or scaffold-hopping in cross-docking scenarios.
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Performs 3D shape-based similarity searching using ROCS (OpenEye), USRCAT (ultra-fast), Open3DAlign (RDKit), ESPSim (electrostatic), and ShaEP with explicit handling of Tanimoto-Combo (shape + color), shape vs ECFP4 complementarity, conformer-ensemble searching, alignment optimization, and scaffold hopping. Use when searching for shape-mimicking compounds with different scaffolds, identifying bioisosteric replacements, prospective scaffold hopping, or expanding hit series beyond 2D similarity.
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