“php”的搜索结果

Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.

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Stability Patterns knowledge base. Provides patterns, antipatterns, and PHP-specific guidelines for Circuit Breaker, Retry, Rate Limiter, Bulkhead, and resilience audits.

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Layered Architecture knowledge base. Provides patterns, antipatterns, and PHP-specific guidelines for traditional N-tier/Layered Architecture audits.

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Generates DDD Repository interfaces and implementation stubs for PHP 8.5. Creates domain interfaces in Domain layer, implementation in Infrastructure.

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Generates CQRS Queries and Handlers for PHP 8.5. Creates read-only query DTOs with handlers that return data without side effects. Includes unit tests.

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Hexagonal Architecture (Ports & Adapters) knowledge base. Provides patterns, antipatterns, and PHP-specific guidelines for Hexagonal Architecture audits.

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Generates Getting Started guides for PHP projects. Creates step-by-step tutorials for first-time users.

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Event Sourcing knowledge base. Provides patterns, antipatterns, and PHP-specific guidelines for Event Sourcing architecture audits.

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Generates Rate Limiter pattern for PHP 8.5. Creates request throttling with token bucket, sliding window, and fixed window algorithms. Includes unit tests.

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Generates PSR-6 Cache implementation for PHP 8.5. Creates CacheItemPoolInterface and CacheItemInterface implementations with TTL handling and deferred saves. Includes unit tests.

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Generates PSR-18 HTTP Client implementation for PHP 8.5. Creates ClientInterface with request sending and exception handling. Includes unit tests.

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Outbox Pattern knowledge base. Provides patterns, antipatterns, and PHP-specific guidelines for transactional outbox, polling publisher, and reliable messaging audits.

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GRASP principles knowledge base for PHP 8.5 projects. Provides quick reference for 9 responsibility assignment patterns (Information Expert, Creator, Controller, Low Coupling, High Cohesion, Polymorphism, Pure Fabrication, Indirection, Protected Variations). Use for architecture audits and design decisions.

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DDD architecture knowledge base. Provides patterns, antipatterns, and PHP-specific guidelines for Domain-Driven Design audits.

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Detects test antipatterns and code smells in PHP test suites. Identifies 15 smells (Logic in Test, Mock Overuse, Fragile Tests, Mystery Guest, etc.) with fix recommendations and refactoring patterns for testability.

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Detects code smells in PHP codebases. Identifies God Class, Feature Envy, Data Clumps, Long Parameter List, Long Method, Primitive Obsession, Message Chains, Inappropriate Intimacy. Generates actionable reports with refactoring recommendations.

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Generates Application Use Cases for PHP 8.5. Creates orchestration services that coordinate domain objects, handle transactions, and dispatch events. Includes unit tests.

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Generates Read Model/Projection for PHP 8.5. Creates optimized query models for CQRS read side with projections and denormalization. Includes unit tests.

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Generates Test Data Builder and Object Mother patterns for PHP 8.5. Creates fluent builders with sensible defaults and factory methods for test data creation.

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Generates Retry pattern for PHP 8.5. Creates resilience component with exponential backoff, jitter, and configurable retry strategies. Includes unit tests.

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Generates State pattern for PHP 8.5. Creates state machines with context, state interface, and concrete states for behavior changes. Includes unit tests.

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Generates Strategy pattern for PHP 8.5. Creates interchangeable algorithm families with context class, strategy interface, and concrete implementations. Includes unit tests.

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Generates Saga pattern components for PHP 8.5. Creates Saga interfaces, steps, orchestrator, state management, and compensation logic with unit tests.

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Generates DDD Specification for PHP 8.5. Creates reusable business rule objects for validation, filtering, and querying with composite pattern support. Includes unit tests.

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