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Analyze single-cell RNA-seq data with Scanpy, from quality checks and normalization to cell grouping, exploratory marker genes, and plots. Bundled scripts also prepare sample-level count summaries and support conversion of R objects to h5ad.

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• Check data quality and normalize single-cell measurements
• Visualize cell groups with UMAP or t-SNE
• Explore marker genes and review cell-type labels

Use Kanpeki component library in React projects. Activate when user wants to add, use, customize, or compose accessible UI components from Kanpeki (@kanpeki/*). Triggers: shadcn CLI, copy-paste components, Field.Root, composeRenderProps, ~/components/ui/*, React Aria Components + Tailwind CSS 4.1 + CVA. Covers installation, component patterns, forms (React Hook Form, TanStack Form), theming, and dark mode.

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Use Kanpeki component library in React projects. Activate when user wants to add, use, customize, or compose accessible UI components from Kanpeki (@kanpeki/*). Covers installation, component patterns, forms, theming, and dark mode with React Aria Components + Tailwind CSS 4.1 + CVA.

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Use Kanpeki component library in React projects. Activate when user wants to add, use, customize, or compose accessible UI components from Kanpeki (@kanpeki/*). Covers installation, component patterns, forms, theming, and dark mode with React Aria Components + Tailwind CSS 4.1 + CVA.

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Estimate RNA velocity, the modeled direction of gene expression change, from single-cell spliced and unspliced counts. Fit models, inspect gene-level plots, visualize trajectories, and explore relative timing and associated genes while checking model limitations.

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• Explore hypotheses about directions of cell-state change
• Inspect gene-level RNA velocity model fits
• Estimate relative cell ordering with a dynamical model

Query public single-cell and spatial gene expression data by tissue, disease, or cell type. Retrieve selected expression values, cell metadata, and summary counts for analysis and comparisons across datasets without first downloading entire collections.

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• Explore cell types within a tissue
• Retrieve expression values for selected marker genes
• Compare cells across tissues and datasets

Organize single-cell measurements with cell and gene metadata, read and write h5ad or Zarr files, and prepare subsets or combined datasets. Includes guidance on handling large annotated matrices without loading all measurement values into memory.

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• Read and write h5ad or Zarr datasets
• Combine experimental batches with source labels
• Select cells or genes using metadata

Check single-cell RNA-seq data quality, filter low-quality cells using median absolute deviation, a measure of spread, and compare plots before and after filtering. Outputs include filtered data and the original dataset with quality annotations.

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• Assess single-cell RNA-seq data quality
• Filter low-quality cells and rarely detected genes
• Compare quality plots before and after filtering

Für Rechtsabteilung: Preisanpassung bei Dauerverträgen nach Energiekosten-Schock: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Prüfprodukt mit Risiko und nächstem Schritt. Fachgebiet: AGB-Recht-Prüfer. Route: rechtsabteilung-preisanpassung-bei-dauervertraegen-nach-energiek.

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Für Rechtsabteilung: Preisanpassung bei Dauerverträgen nach Energiekosten-Schock: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Prüfprodukt mit Risiko und nächstem Schritt. Fachgebiet: AGB-Recht-Prüfer. Route: rechtsabteilung-preisanpassung.

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Guides compliance with Brazil's Lei Geral de Proteção de Dados (LGPD, Lei 13.709/2018). Covers the 10 lawful bases under Art. 7, DPO appointment, ANPD enforcement, data subject rights under Arts. 17-22, and international transfer mechanisms. Keywords: LGPD, Brazil data protection, ANPD, lawful bases, data subject rights, international transfers.

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Fit probabilistic models to single-cell measurements for integration across experiments, cell annotation, combined RNA and protein or ATAC analysis, and gene expression comparisons. The skill covers input requirements, training checks, reference mapping, and interpretation of model uncertainty.

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• Integrating single-cell RNA data across experimental batches
• Assigning cell labels using partial annotations or a reference
• Analyzing RNA with protein or ATAC measurements

Für Mahngebühren und Zinsanpassung AGB: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Berechnungstabelle mit Annahmen und Kontrollfragen.

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Für AGB Preisanpassung Energie Stromgvv Gasgvv: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Prüfprodukt mit Risiko und nächstem Schritt.

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Expert LGPD compliance advisor for Brazil's Lei Geral de Proteção de Dados (Law 13,709/2018). Use this skill whenever a user asks about LGPD, Brazilian data protection, ANPD, personal data processing in Brazil, data subject rights under Brazilian law, legal bases for processing, sensitive data handling, DPO appointment in Brazil, data breach notification to ANPD, LGPD penalties (fines up to 2% of revenue / R$50M), international data transfers from Brazil, Brazil-EU mutual adequacy (January 2026 — SCCs/BCRs no longer needed for Brazil-EU transfers), LGPD gap assessments, privacy policy drafting for Brazilian operations, DPIA under LGPD, consent management, or comparing LGPD with GDPR. Trigger for any Brazil privacy or data protection question even if LGPD is not named explicitly.

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Expert LGPD compliance advisor for Brazil's Lei Geral de Proteção de Dados (Law 13,709/2018). Use this skill whenever a user asks about LGPD, Brazilian data protection, ANPD, personal data processing in Brazil, data subject rights under Brazilian law, legal bases for processing, sensitive data handling, DPO appointment in Brazil, data breach notification to ANPD, LGPD penalties (fines up to 2% of revenue / R$50M), international data transfers from Brazil, Brazil-EU mutual adequacy (January 2026 — SCCs/BCRs no longer needed for Brazil-EU transfers), LGPD gap assessments, privacy policy drafting for Brazilian operations, DPIA under LGPD, consent management, or comparing LGPD with GDPR. Trigger for any Brazil privacy or data protection question even if LGPD is not named explicitly.

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Dung khi can MO va thiet lap kenh marketing tu con so khong — TikTok Brand, Zalo OA, Fanpage, Instagram Business, Google Business Profile, TikTok Shop, tai khoan email: checklist setup 4 giai doan, thong so ky thuat, lien ket cheo va ke hoach 30 ngay dau. Kich hoat khi user nhac 'thiet lap kenh', 'tao fanpage moi', 'dang ky Zalo OA', 'mo TikTok Shop', 'setup kenh tu dau', 'chua co kenh nao het', 'kenh moi lap nen lam gi truoc', 'mo kenh moi'. Khong dung cho — cau truc tai khoan quang cao thi dung skill 52-account-structure; gan pixel va do chuyen doi thi dung skill 53-tracking-setup; len lich dang bai thi dung skill 01-lich-noi-dung; van hanh email va Zalo broadcast thi dung skill 14-email-marketing.

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scRNA-seq with Scanpy: QC, normalization, HVG selection, PCA, neighborhood graph, UMAP/t-SNE, Leiden clustering, markers, cell annotation, trajectory inference. Standard scRNA-seq exploration.

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統計的推論（線形回帰 / 重回帰 / OLS / Lasso / Ridge / 分位点回帰、ロジスティック回帰 / ポアソン / GLM / オッズ比、 混合効果 / マルチレベル / パネル固定効果、仮説検定 / t 検定 / χ² / ANOVA / 有意差、生存時間分析 / Kaplan-Meier / Cox、 ベイズ推定 / MCMC / Stan）を実行したら必ずセットで出す図と値のルーター。sm.OLS, smf.ols, LinearRegression, LassoCV, QuantReg, sm.Logit, sm.GLM, LogisticRegression, mixedlm, PanelOLS, ttest_ind, mannwhitneyu, chi2_contingency, pingouin, lifelines, CoxPHFitter, cmdstanpy, arviz がコードに現れたとき、またはユーザーが「回帰して」「検定して」 「有意差はあるか」「生存曲線を描いて」「ベイズで推定して」と言ったときに使う。診断・残差・図に言及がなくても適用する。 SKILL.md のルーティング表で手法を特定し、対応する references/<手法>.md を読んでから実行する。A/B テスト・因果推論は causal-inference-diagnostics、予測 ML・時系列は predictive-modeling-diagnostics を使う。

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店長が承認した発注案を、発注単位・締め時刻・便を確かめてから Dataverse の発注テーブルに登録し、登録結果を報告するスキル。承認の前に必ず最終の一覧（Render UI のグラフ付き）を見せ、登録後は HTML レポート「発注の記録」を作る。 Use when ユーザーが「この内容で発注して」「承認します」「発注を登録して」「さっきの発注はどうなった？」と依頼したとき、または tanpin-kanri の発注案が承認されたとき。 Dataverse MCP コネクタ（describe / read_query / create_record）を使う。create_record はこのスキルでだけ、店長の明示的な承認の後に、発注テーブルにだけ使う。

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Bridge layer connecting the emerging agentic coordination protocol ecosystem (MCP, A2A, ANP, AGNTCY, AITP, LMOS, AAIF) to the plurigrid/asi skill graph. Maps protocol-level identity mechanisms (W3C DID, OAuth 2.1, IPSIE, Entra Agent ID, Agent Cards, passport.gay) into GF(3)-classified skills. The central unsolved problem — no unified identity across MCP+A2A+A2UI — is directly addressed by the bisimulation oracle composition.

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Comprehensive research corpus covering 40+ agentic coordination protocols and ecosystems (MCP, A2A, ANP, UCP, ACP, AGNTCY, NANDA, FIPA, WoT, etc.) with emphasis on identity architectures, governance bodies, and interoperability convergence patterns.

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Voegt een proof-of-concept toe aan het poc-portaal op poc.regelrecht.rijks.app — register-entry, map-indeling, de subpad-aanpassingen die een losse app nodig heeft om onder /<slug>/ te draaien, en de bedrading in de deploy. Gebruik dit bij "voeg poc X toe", het verhuizen van een losse PoC-repo naar de monorepo, of het aanpassen van status en voorbehoud van een bestaande poc.

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Scanpy is a scalable Python toolkit for analyzing single-cell RNA-seq data, built on AnnData. Apply this skill for complete single-cell workflows including quality control, normalization, dimensionality reduction, clustering, marker gene identification, visualization, and trajectory analysis.

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