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Develop a high-performance liquid chromatography method: define separation goals, select column chemistry and mobile phase, optimize gradient and flow conditions, choose the appropriate detector, and evaluate initial method performance for target analytes in solution or complex matrices.
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Develop a gas chromatography method from scratch: define analytical objectives, select column chemistry, optimize temperature programming, choose carrier gas and detector, and validate initial system performance for target analytes in a given matrix.
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SEC (size-exclusion chromatography) analysis with peak detection, oligomer classification, and publication-quality PDF report generation via Typst templates. Triggers on "SEC", "size exclusion", "chromatography", "oligomer analysis", "protein assembly", "SEC report".
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Spectroscopy, chromatography, titration, elemental analysis, X-ray crystallography, and mass spectrometry for chemical identification and quantitation. Covers UV-Vis and IR spectroscopy, NMR fundamentals, gas and liquid chromatography, gravimetric and volumetric analysis, diffraction methods, separation techniques, and quantitative error analysis. Use when identifying unknown substances, determining purity, measuring concentrations, or interpreting analytical data.
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Expert-level analytical chemistry knowledge. Use when working with chromatography, spectroscopy, electroanalytical methods, sample preparation, quantitative analysis, calibration, statistics, or instrumental analysis. Also use when the user mentions 'HPLC', 'GC', 'mass spectrometry', 'atomic absorption', 'ICP', 'titration', 'calibration curve', 'detection limit', 'NMR', 'chromatography', 'electrochemistry', 'sample preparation', or 'method validation'.
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Interpret a chromatogram from GC or HPLC analysis: verify system suitability parameters, identify peaks by retention time and spectral matching, perform accurate peak integration, calculate chromatographic figures of merit, and assess overall peak quality for reliable quantitation.
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