“downstream”的搜索结果

在REGRESSION.md中整理模块依赖关系与验证命令，沿修改影响范围执行测试或数据核对，并以命令退出码报告结果，检查现有功能是否受到破坏。

• 验证模块修改的影响范围
• 按模块整理现有测试
• 审计依赖依据与验证范围

Assess how changes, failures, or paused updates to a BigQuery table or view affect downstream assets. Trace data lineage, the relationships showing where data flows, and summarize dependent tables, dashboards, and processes with direct and indirect impacts.

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• Assess downstream effects of a table failure
• Check dependencies before changing or deleting a view
• Evaluate the impact of pausing data updates

Trace where BigQuery and Cloud Storage data comes from and where it goes. The skill summarizes table or column lineage, meaning data origins and movement, in a readable Markdown report to support data quality investigations.

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• Investigating data origins during a quality issue
• Summarizing data sources and destinations
• Tracing the flow of a specific column

Summarizes Google Cloud Data Lineage graphs to help users debug data quality issues and understand data provenance for BQ/GCS. Use when summarizing upstream and downstream data flows, and presenting complex lineage data as an intuitive Markdown report. Don't use for generic BigQuery queries, editing lineage relationships, or downstream deprecation. Don't use for downstream blast-radius impact analysis (use datalineage-bigquery-asset-impact-analysis skill instead).

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Analyzes the downstream impact (blast radius) when a BigQuery table or view is broken, stale, or modified. Identifies all downstream tables, dashboards, and processes that will be affected. Use when: - Performing a blast radius or impact analysis for a BigQuery table or view. - Assessing the consequences of modifying, deleting, or pausing updates to a BigQuery asset. - Identifying downstream dependencies (tables, dashboards, processes) of a BigQuery asset. Don't use for: - General BigQuery querying or data analysis (use BigQuery-related tools instead). - Non-BigQuery assets (e.g., Cloud Storage files) unless they are part of the BigQuery lineage. - Creating or modifying lineage links directly.

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Applies standard AI review policy guidelines for downstream (test/QA) phase reviews.

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Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq c_curve / lc_extrap, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT — see Tips), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for downstream cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for downstream visualisation.

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Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq c_curve / lc_extrap, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT — see Tips), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for downstream cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for downstream visualisation.

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Record migration instructions for Prisma 8 breaking changes alongside the pull request. Prepare separate guidance for application users and extension authors, with optional code transformation scripts and checks that reproduce the required changes.

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• Documenting migration steps for a breaking change
• Preparing separate app and extension upgrade guidance
• Testing migration scripts against pre-change code

Trace queued jobs from submission to their eventual effects in a CTF sandbox. Compare request-time and worker-time settings, follow retries and failed-message handling, and document the smallest sequence that explains a worker-specific result.

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• Trace a queued payload to its eventual downstream effect
• Compare request-time settings with worker runtime state
• Investigate retries and dead-letter queue handling

Review Apache ShardingSphere pull requests or authorized downstream changes using repository evidence. Assess code correctness, merge readiness, or CI failures, then produce consolidated findings or a ready-to-copy reply to a review discussion.

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• Review code changes for correctness and regression risks
• Assess whether a pull request is ready to merge
• Investigate CI failures

Refines broad, vague, or aspirational biomedical research objectives into clear, bounded, measurable, executable, and downstream-ready study objective statements. Always use this skill when a user has a general aim such as “explore a mechanism,” “study prognosis,” “investigate biomarkers,” or “look at treatment response,” but the objective is still too broad, non-operational, or too ambiguous to support protocol framing, design selection, analysis planning, or hypothesis design. Never assume that polished wording alone means the objective is actionable. Focus first on objective type, missing operational elements, scope discipline, and downstream-ready formulation.

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Clarifies a vague clinical or biomedical research idea into a structured, bounded, searchable, researchable, and testable question. Always use this skill whenever a user has an early-stage clinical or research thought, an over-broad topic, an ill-defined evidence question, or an unclear problem statement that must be translated into a question framing suitable for literature retrieval, evidence synthesis, gap analysis, study design, or downstream protocol planning. Never jump straight to answering the substantive medical question unless the user explicitly asks for that. Focus first on question framing, boundary setting, and downstream-ready formulation.

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Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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Trace relationships between semantic models and downstream reports across Fabric workspaces. Automatically invoke when the user asks to "find downstream reports", "show report lineage", "impact analysis", "what depends on this dataset", "cross-workspace lineage", "which reports are connected", "get model dependencies", or mentions model-to-report dependency tracing.

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Walk the user through four directional axes (tone register, aesthetic philosophy, audience relationship, sensory ambition) and produce a structured aesthetic brief that downstream content, copy, design, and art-direction skills consume as required input. The aesthetic depth layer, distinct from `creative-brief` (operational kickoff: scope, audience, deliverables, constraints). Use when a project needs aesthetic coherence across many small decisions and the user has only a vague feeling, or when multiple downstream aesthetic-producing skills need a shared brief. Triggers on creative direction, aesthetic direction, set the aesthetic, define the visual direction, what's the vibe, what's the tone, the four axes. Does NOT fire for a general kickoff brief (use `creative-brief`), tactical single-piece work, already-documented direction, purely functional output, or locked production-stage work.

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Verify ASP.NET Web services build the right IDownstreamApi route and payload without standing up HTTP

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On-Behalf-Of (OBO) Flow for web APIs to call downstream APIs while preserving user identity in MSAL.NET

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Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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Use when reviewing a .NET pull request for breaking changes that may affect other microservice repositories. Detects cross-repo API, DTO, endpoint, EF entity, and NuGet-package breaks, and checks whether a compatible downstream PR already exists. Keywords: cross-repo impact, breaking change, microservice compatibility, downstream break, compatible PR, blast radius review, api compatibility, contract break, dto shape change, endpoint break.

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Evaluates downstream tests for coverage and edge cases.

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Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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Cascade merge changes through a chain of dependent branches. Use when updating stacked/chained PRs, propagating changes from a parent branch to all downstream branches, or when the user mentions "cascade merge", "propagate changes", "update dependent branches", or "merge to downstream branches".

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Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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