使用gget查询基因信息、获取核苷酸和氨基酸序列,搜索相似序列并探索基因集的功能及疾病关联,同时保存结果和查询条件,便于日后核查研究记录。
- 查询基因ID与转录本信息
- 获取核苷酸和氨基酸序列
- 使用BLAST或BLAT进行小规模搜索
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使用gget查询基因信息、获取核苷酸和氨基酸序列,搜索相似序列并探索基因集的功能及疾病关联,同时保存结果和查询条件,便于日后核查研究记录。
Plan and write literature reviews using multiple scholarly databases. Document searches, screen papers, synthesize findings, and check citations, then prepare Markdown or PDF reports with transparent selection counts, evidence limitations, and reproducible search records.
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Check an MCP server before release through a real client session. Compare available features with source code and documentation, test invalid requests and installation, and produce a verdict backed by reproducible commands and responses.
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Evaluate language models on knowledge, math, coding, safety, and image understanding benchmarks. The skill guides reproducible runs in containers using local Docker, Slurm clusters, or cloud execution, with shared configurations for model comparison and result export.
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Validate security patches by comparing vulnerable and patched code against exploit tests, related attack variants, and normal behavior. Produce reproducible logs showing remaining flaws, regressions, newly introduced security failures, and gaps that still need testing.
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Prioritizes candidate genes from GWAS, studies linking genetic variants to traits. Combines locus predictions, gene expression evidence, and rare variant support into ranked results with source attribution, confidence labels, reproducible files, and optional figures.
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This skill covers reproducible research pipelines and replication packages. Use when the user is setting up a research project directory structure, configuring workflow managers (Make, Snakemake, DVC), managing computational environments, preparing replication packages for journal submission, or debugging reproducibility failures. Triggers on "reproducible", "replication package", "Makefile", "Snakemake", "DVC", "pipeline", "workflow manager", "data versioning", "conda environment", "Docker", "seed management", "AEA data editor", "replication", "project structure", or "submission checklist".
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Enhancement overlay — version the WHOLE deployable LLM-app artifact as one bundle: prompts + compiled programs + model snapshot pins + retrieval config + eval-set version, versioned together so a deploy is reproducible and rollback is atomic. Activate when preparing to deploy an LLM app, when asking "what exactly is running in prod right now?", when a deploy must be reproducible months later, or when an incident needs a clean rollback. The core reframe: an LLM app artifact is NOT an ML model — it is a manifest over many independently-mutable parts, not one weights file. Do NOT activate for one-off prompt edits with no deploy, for a single-component demo, or where a vendor owns the whole prompt lifecycle. For versioning ONE compiled prompt use [[agentsop-per-model-artifacts]]; for the CI comparison mechanism use [[agentsop-regression-gate]]. Search keywords: prompt versioning, reproducible deploy, what is running in prod, rollback LLM app, model pinning, prompt registry, version prompts and config.
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Define reproducible development environments with Dev Containers. Use when a user asks to standardize dev environments, set up VS Code remote containers, create reproducible dev setups, or onboard developers faster.
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Create a Quarto document for reproducible reports, presentations, or websites. Covers YAML configuration, code chunk options, output formats, cross-references, and rendering. Use when creating a reproducible analysis report, building a presentation with embedded code, generating HTML, PDF, or Word documents from code, or migrating an existing R Markdown document to Quarto.
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Create reproducible, cross-platform development environments with Flox — a declarative environment manager built on Nix. ALWAYS use this skill when the user needs to: set up a project with system-level dependencies (compilers, databases, native libraries like openssl, libvips, BLAS, LAPACK); configure reproducible toolchains for Python, Node.js, Rust, Go, C/C++, Java, Ruby, Elixir, PHP, or any language; manage environments that must work identically across macOS and Linux; pin exact package versions for a team; run local services (PostgreSQL, Redis, Kafka) alongside development tools; onboard new developers with a single command; or solve 'works on my machine' problems. Especially valuable for AI-assisted and vibe coding — Flox lets agents install tools into a project-scoped environment without sudo, system pollution, or sandbox restrictions, and the resulting environment is committed to the repo so anyone can reproduce it instantly. Use this skill even if the user doesn't mention Flox — if they describe needing reproducible, declarative, cross-platform dev environments with system packages, this is the right tool. Also use when the user mentions .flox/, manifest.toml, flox activate, or FloxHub.
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使用 Flox 将开发工具、数据库、版本及配置集中到文件中,建立可在 macOS 和 Linux 上复现的开发环境,并与团队共享或为智能体添加项目工具。
将性能优化拆解为现状测量、单个假设的方案比较和正确性验证,在时间与费用上限内选出测得最快且安全的方案,并保留可重复执行的命令、配置和记录。
对已获授权的Web应用开展漏洞调查,从公开页面、输入和认证机制入手,验证可复现的问题,并生成包含证据、影响、复现步骤及修复建议的安全报告。
Create videos programmatically with React for branded explainers, short social clips, and dashboard visuals. Use code to define motion graphics that can be reproduced through the same workflow.
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Create generative art, or images made with programmed rules, using p5.js. Fixed random seeds make each rendering reproducible, supporting procedural posters, still images that suggest motion, and studies of artistic frame composition.
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Build and test SimPy models of queues, production, logistics, and other event-driven systems. Set execution limits, monitor waiting times and resource use, and analyze repeated runs with recorded random seeds for reproducible results.
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Simulate concentration changes over time from biochemical models in SBML or Antimony, and compare fixed parameter conditions. Checks model units and exports CSV results plus COMBINE archives containing models and experiment settings, then replays them to compare results.
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Build and evaluate single-agent reinforcement learning experiments, where an agent learns actions from rewards. Use Stable Baselines3 to choose algorithms, create environments, monitor training, and save models with the normalization data needed for consistent evaluation.
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Calculate equilibrium phases, their molar fractions, and compositions from a local thermodynamic database using pycalphad. Compare temperatures, check material balance and sampling stability, and export results with recorded conditions and database identifiers.
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Build and review numerical workflows for MATLAB or GNU Octave, including arrays, tables, graphics, tests, and MAT files. Helps plan release migrations, reproducible projects, and Python integration while checking runtime, compatibility, and license requirements.
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Build and operate genomics workloads on DNAnexus using its command-line tools and Python SDK. The skill covers data transfers, app configuration checks, workflow imports, execution monitoring, and explicit cost controls for reproducible analysis workflows.
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Turn a theme into generative art, artwork created by computational rules, using p5.js. Receive a written artistic philosophy and an interactive HTML viewer with adjustable parameters, reproducible variations, and PNG download controls.
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Analyze encrypted ZIP challenges in a CTF sandbox and use bkcrack to recover legacy ZipCrypto keys from known file contents. Create a decrypted archive, validate extraction, and preserve the commands and evidence needed to reproduce the result.
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