FHIR Developer Skill

Quick Reference

HTTP Status Codes

Code	When to Use
200 OK	Successful read, update, or search
201 Created	Successful create (include Location header)
204 No Content	Successful delete
400 Bad Request	Malformed JSON, wrong resourceType
401 Unauthorized	Missing, expired, revoked, or malformed token (RFC 6750)
403 Forbidden	Valid token but insufficient scopes
404 Not Found	Resource doesn't exist
412 Precondition Failed	If-Match ETag mismatch (NOT 400!)
422 Unprocessable Entity	Missing required fields, invalid enum values, business rule violations

Required Fields by Resource (FHIR R4)

Resource	Required Fields	Everything Else
Patient	(none)	All optional
Observation	status, code	Optional
Encounter	status, class	Optional (including subject, period)
Condition	subject	Optional (including code, clinicalStatus)
MedicationRequest	status, intent, medication[x], subject	Optional
Medication	(none)	All optional
Bundle	type	Optional

---

Required vs Optional Fields (CRITICAL)

Only validate fields with cardinality starting with "1" as required.

Cardinality	Required?
0..1, 0..*	NO
1..1, 1..*	YES

Common mistake: Making subject or period required on Encounter. They are 0..1 (optional).

---

Value Sets (Enum Values)

Invalid enum values must return 422 Unprocessable Entity.

Patient.gender

male | female | other | unknown

Observation.status

registered | preliminary | final | amended | corrected | cancelled | entered-in-error | unknown

Encounter.status

planned | arrived | triaged | in-progress | onleave | finished | cancelled | entered-in-error | unknown

Encounter.class (Common Codes)

Code	Display	Use
AMB	ambulatory	Outpatient visits
IMP	inpatient encounter	Hospital admissions
EMER	emergency	Emergency department
VR	virtual	Telehealth

Condition.clinicalStatus

active | recurrence | relapse | inactive | remission | resolved

Condition.verificationStatus

unconfirmed | provisional | differential | confirmed | refuted | entered-in-error

MedicationRequest.status

active | on-hold | cancelled | completed | entered-in-error | stopped | draft | unknown

MedicationRequest.intent

proposal | plan | order | original-order | reflex-order | filler-order | instance-order | option

Bundle.type

document | message | transaction | transaction-response | batch | batch-response | history | searchset | collection

---

Validation Pattern

Python/FastAPI:

from fastapi import FastAPI
from fastapi.responses import JSONResponse

app = FastAPI()

def operation_outcome(severity: str, code: str, diagnostics: str):
    return {
        "resourceType": "OperationOutcome",
        "issue": [{"severity": severity, "code": code, "diagnostics": diagnostics}]
    }

VALID_OBS_STATUS = {"registered", "preliminary", "final", "amended",
                    "corrected", "cancelled", "entered-in-error", "unknown"}

@app.post("/Observation", status_code=201)
async def create_observation(data: dict):
    if not data.get("status"):
        return JSONResponse(status_code=422, content=operation_outcome(
            "error", "required", "Observation.status is required"
        ), media_type="application/fhir+json")

    if data["status"] not in VALID_OBS_STATUS:
        return JSONResponse(status_code=422, content=operation_outcome(
            "error", "value", f"Invalid status '{data['status']}'"
        ), media_type="application/fhir+json")
    # ... create resource

TypeScript/Express:

const VALID_OBS_STATUS = new Set(['registered', 'preliminary', 'final', 'amended',
  'corrected', 'cancelled', 'entered-in-error', 'unknown']);

app.post('/Observation', (req, res) => {
  if (!req.body.status) {
    return res.status(422).contentType('application/fhir+json')
      .json(operationOutcome('error', 'required', 'Observation.status is required'));
  }
  if (!VALID_OBS_STATUS.has(req.body.status)) {
    return res.status(422).contentType('application/fhir+json')
      .json(operationOutcome('error', 'value', `Invalid status '${req.body.status}'`));
  }
  // ... create resource
});

Pydantic v2 Models (use Literal, not const=True):

from typing import Literal
from pydantic import BaseModel

class Patient(BaseModel):
    resourceType: Literal["Patient"] = "Patient"
    id: str | None = None
    gender: Literal["male", "female", "other", "unknown"] | None = None

---

Coding Systems (URLs)

System	URL
LOINC	http://loinc.org
SNOMED CT	http://snomed.info/sct
RxNorm	http://www.nlm.nih.gov/research/umls/rxnorm
ICD-10	http://hl7.org/fhir/sid/icd-10
v3-ActCode	http://terminology.hl7.org/CodeSystem/v3-ActCode
Observation Category	http://terminology.hl7.org/CodeSystem/observation-category
Condition Clinical	http://terminology.hl7.org/CodeSystem/condition-clinical
Condition Ver Status	http://terminology.hl7.org/CodeSystem/condition-ver-status

Common LOINC Codes (Vital Signs)

Code	Description
8867-4	Heart rate
8480-6	Systolic blood pressure
8462-4	Diastolic blood pressure
8310-5	Body temperature
2708-6	Oxygen saturation (SpO2)

---

Data Type Patterns

Coding (direct) vs CodeableConcept (wrapped)

Coding - Used by Encounter.class:

{"system": "http://terminology.hl7.org/CodeSystem/v3-ActCode", "code": "AMB"}

CodeableConcept - Used by Observation.code, Condition.code:

{"coding": [{"system": "http://loinc.org", "code": "8480-6"}], "text": "Systolic BP"}

Reference

{"reference": "Patient/123", "display": "John Smith"}

Identifier

{"system": "http://hospital.example.org/mrn", "value": "12345"}

---

Common Mistakes

Mistake	Correct Approach
Making subject or period required on Encounter	Both are 0..1 (optional). Only status and class are required
Using CodeableConcept for Encounter.class	class uses Coding directly: {"system": "...", "code": "AMB"}
Returning 400 for ETag mismatch	Use 412 Precondition Failed for If-Match failures
Returning 400 for invalid enum values	Use 422 Unprocessable Entity for validation errors
Forgetting Content-Type header	Always set Content-Type: application/fhir+json
Missing Location header on create	Return Location: /Patient/{id} with 201 Created

---

Resource Structures

For complete JSON examples of all resources, see references/resource-examples.md.

Quick reference for error responses:

{
  "resourceType": "OperationOutcome",
  "issue": [{"severity": "error", "code": "not-found", "diagnostics": "Patient/123 not found"}]
}

---

RESTful Endpoints

POST   /[ResourceType]              # Create (returns 201 + Location header)
GET    /[ResourceType]/[id]         # Read
PUT    /[ResourceType]/[id]         # Update
DELETE /[ResourceType]/[id]         # Delete (returns 204)
GET    /[ResourceType]?param=value  # Search (returns Bundle)
GET    /metadata                    # CapabilityStatement
POST   /                            # Bundle transaction/batch

---

Conditional Operations

If-Match (optimistic locking):

• Client sends: If-Match: W/"1"
• Mismatch returns 412 Precondition Failed

If-None-Exist (conditional create):

• Client sends: If-None-Exist: identifier=http://mrn|12345
• Match exists: return existing (200)
• No match: create new (201)

---

Reference Files

For detailed guidance, see:

• Resource Examples: Complete JSON structures for Patient, Observation, Encounter, Condition, MedicationRequest, OperationOutcome, CapabilityStatement
• SMART on FHIR Authorization: OAuth flows, scope syntax (v1/v2), backend services, scope enforcement
• Pagination: Search result pagination, _count/_offset parameters, link relations
• Bundle Operations: Transaction vs batch semantics, atomicity, processing order

---

Implementation Checklist

1. Set Content-Type: application/fhir+json on all responses
2. Return meta.versionId and meta.lastUpdated on resources
3. Return Location header on create: /Patient/{id}
4. Return ETag header: W/"{versionId}"
5. Use OperationOutcome for all error responses
6. Validate required fields → 422 for missing
7. Validate enum values → 422 for invalid
8. Search returns Bundle with type: "searchset"

---

Quick Start Script

To scaffold a new FHIR API project with correct Pydantic v2 patterns:

python scripts/setup_fhir_project.py my_fhir_api

Creates a FastAPI project with correct models, OperationOutcome helpers, and Patient CRUD endpoints.