AI-powered adeno-associated virus (AAV) vector design for gene therapy including capsid engineering, promoter selection, and tropism optimization.
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Build high-quality MCP servers with strong tool design, structured outputs, clear error handling, and realistic evaluations. Use when creating or improving MCP servers in TypeScript or Python for external APIs, services, or internal platforms.
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查看安装方法安装前可以查看交给 AI 代理的指令内容。
Design MCP servers that are easy for agents to discover, compose, and trust.
Use symptom -> action triggers: when one matches, apply this skill and verify with the protocol below.
Before implementation:
Prefer tools that are easy to discover and compose:
Build common pieces before individual tools:
Verify more than syntax:
A strong MCP server needs realistic read-only evaluations:
// Before
async function listTickets(page = 1) {
return api.get(`/tickets?page=${page}`)
}
// After
export async function paginate<T>(fetchPage: (cursor?: string) => Promise<{ items: T[]; nextCursor?: string }>) {
const items: T[] = [];
let cursor: string | undefined;
do {
const page = await fetchPage(cursor);
items.push(...page.items);
cursor = page.nextCursor;
} while (cursor);
return items;
}
// Before
throw new Error(`Request failed: ${response.status}`)
// After
throw formatToolError({
code: 'tickets.list_failed',
message: 'Unable to list tickets for the requested project.',
status: response.status,
nextAction: 'Check the project id and retry with a smaller page size.',
})
// Before
server.tool('create_ticket', { title: z.string(), priority: z.string() }, handler)
// After
const prioritySchema = z.enum(['low', 'medium', 'high']);
const ticketInput = buildToolSchema({
title: z.string().min(1),
priority: prioritySchema.default('medium'),
});
server.tool('create_ticket', ticketInput, handler)
Prefer TypeScript when you want the strongest SDK ergonomics and schema-heavy tool definitions.
Primary references:
Prefer Python when the target ecosystem or existing service code is already Python-heavy.
Primary references:
Minimize scopes, redact secrets from errors, and keep authorization checks inside shared request middleware instead of duplicating them per tool.
Log request identifiers, tool names, latency, and retry counts so agent failures can be traced without replaying everything manually.
Support token refresh or credential reload paths explicitly so agents get actionable failures instead of opaque 401 loops.
Prefer structured logs with stable fields such as tool, resource, status, and duration_ms over free-form strings.
Treat tool names, schemas, and error contracts as public interfaces; add versions or deprecation notes before changing them in place.
Before claiming "skill applied successfully":
scripts/connections.pyscripts/evaluation.pyscripts/example_evaluation.xmlThis skill is written to stay usable across GitHub Copilot, Claude Code, and Codex.
$CODEX_HOME/skills/mcp-builder and restart Codex after major changes.Preferred MCP Server: None required
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AI-powered adeno-associated virus (AAV) vector design for gene therapy including capsid engineering, promoter selection, and tropism optimization.
中文简介正在准备中。当前显示原文说明。
Improve the clarity and voice of AI-assisted academic writing (papers, theses, rebuttals) and
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12-agent academic paper writing pipeline. 11 modes (full/plan/outline/revision/revision-coach/abstract/lit-review/format-convert/citation-check/disclosure/rebuttal-audit). 6 paper types, 5 citation formats, bilingual abstracts, LaTeX/DOCX-via-Pandoc/PDF output. Style Calibration + Writing Quality Check + Anti-Patterns with IRON RULE markers. Triggers: write paper, academic paper, guide my paper, parse reviews, audit my rebuttal, check my response draft, AI disclosure, 寫論文, 學術論文, 引導我寫論文, 審查意見, 評估回覆, 논문 작성, 초록 작성, 논문 수정, 논문 계획을 도와줘, 심사 의견 반영, 답변서 점검, AI 사용 고지.
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Systematic writing framework for philosophy and interdisciplinary academic papers from optimized outline to submission-ready manuscript. Use when users want to: (1) write a paper from a detailed outline, (2) ensure quality control during writing, (3) maintain consistency across chapters, (4) prepare a submission-ready manuscript, or (5) systematically execute a planned paper. Triggered by phrases like 'write the paper from this outline,' 'compose the full manuscript,' 'execute the outline,' or when users have completed strategic planning (academic-paper-strategist skill) and are ready to write. Takes optimized outline as input; outputs complete manuscript with iterative quality checks.
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Multi-perspective academic paper review with dynamic reviewer personas. Runs a 5-seat, role-separated review panel (Journal-Fit Reviewer + 3 peer-review roles + Devil's Advocate) with field-specific expertise; role separation is not a claim of independent error processes. Supports full review, re-review (verification), quick assessment, methodology focus, Socratic guided, and calibration modes. Triggers on: review paper, peer review, manuscript review, referee report, review my paper, critique paper, simulate review, editorial review, calibrate reviewer, reviewer calibration, measure reviewer accuracy, 審查論文, 論文審查, 模擬審查, 同儕審查, 幫我審這篇, 以審查人角度評估, 審查者校準, 논문 심사, 동료 심사, 모의 심사, 심사자 관점에서 평가, 심사자 보정.
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Systematic strategic planning framework for philosophy and interdisciplinary academic papers targeting preprint platforms (PhilArchive, arXiv, PhilSci-Archive). Use when users want to: (1) plan a paper on a specific topic, (2) identify research gaps and assess originality, (3) develop optimized paper outlines, (4) prepare for preprint submission, or (5) understand platform requirements and writing standards. Triggered by phrases like 'plan a paper on,' 'help me design a paper about,' 'identify research gaps in,' 'is this idea original,' or when users need structured research planning. The skill guides through three phases: Platform Analysis (identifying target venue and studying sample papers), Theoretical Framework (AI-driven literature search and gap identification), and Outline Optimization (structured design with reviewer-perspective self-assessment). Each phase includes quality evaluation standards and validation checkpoints.
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