跳到正文
cccskills
免费在 GitHub 公开

adaptyv

Support experimental validation of designed proteins through a cloud laboratory. Prepare and optimize sequences, submit tests for binding, expression, thermal stability, or enzyme activity, track experiment progress, and retrieve results through the API.

中文简介正在准备中。当前显示英语简介。

原文查看原文说明

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

实测评分 未实测

查看安装方法

适用场景

  • Submit designed proteins for binding tests
  • Request expression, thermal stability, or enzyme activity tests
  • Optimize sequences for solubility before experiments
  • Track submitted experiments and download results

包含的文件(5)

  • SKILL.md3.6 KB
  • reference/api_reference.md6.5 KB
  • reference/examples.md22.5 KB
  • reference/experiments.md9.7 KB
  • reference/protein_optimization.md17.4 KB

SKILL.md(原文)

安装前可以查看交给 AI 代理的指令内容。

Adaptyv

Adaptyv is a cloud laboratory platform that provides automated protein testing and validation services. Submit protein sequences via API or web interface and receive experimental results in approximately 21 days.

Quick Start

Authentication Setup

Adaptyv requires API authentication. Set up your credentials:

  1. Contact support@adaptyvbio.com to request API access (platform is in alpha/beta)
  2. Receive your API access token
  3. Set environment variable:
export ADAPTYV_API_KEY="your_api_key_here"

Or create a .env file:

ADAPTYV_API_KEY=your_api_key_here

Installation

Install the required package using uv:

uv pip install requests python-dotenv

Basic Usage

Submit protein sequences for testing:

import os
import requests
from dotenv import load_dotenv

load_dotenv()

api_key = os.getenv("ADAPTYV_API_KEY")
base_url = "https://kq5jp7qj7wdqklhsxmovkzn4l40obksv.lambda-url.eu-central-1.on.aws"

headers = {
    "Authorization": f"Bearer {api_key}",
    "Content-Type": "application/json"
}

# Submit experiment
response = requests.post(
    f"{base_url}/experiments",
    headers=headers,
    json={
        "sequences": ">protein1\nMKVLWALLGLLGAA...",
        "experiment_type": "binding",
        "webhook_url": "https://your-webhook.com/callback"
    }
)

experiment_id = response.json()["experiment_id"]

Available Experiment Types

Adaptyv supports multiple assay types:

  • Binding assays - Test protein-target interactions using biolayer interferometry
  • Expression testing - Measure protein expression levels
  • Thermostability - Characterize protein thermal stability
  • Enzyme activity - Assess enzymatic function

See reference/experiments.md for detailed information on each experiment type and workflows.

Protein Sequence Optimization

Before submitting sequences, optimize them for better expression and stability:

Common issues to address:

  • Unpaired cysteines that create unwanted disulfides
  • Excessive hydrophobic regions causing aggregation
  • Poor solubility predictions

Recommended tools:

  • NetSolP / SoluProt - Initial solubility filtering
  • SolubleMPNN - Sequence redesign for improved solubility
  • ESM - Sequence likelihood scoring
  • ipTM - Interface stability assessment
  • pSAE - Hydrophobic exposure quantification

See reference/protein_optimization.md for detailed optimization workflows and tool usage.

API Reference

For complete API documentation including all endpoints, request/response formats, and authentication details, see reference/api_reference.md.

Examples

For concrete code examples covering common use cases (experiment submission, status tracking, result retrieval, batch processing), see reference/examples.md.

Important Notes

  • Platform is currently in alpha/beta phase with features subject to change
  • Not all platform features are available via API yet
  • Results typically delivered in ~21 days
  • Contact support@adaptyvbio.com for access requests or questions
  • Suitable for high-throughput AI-driven protein design workflows

评价

还没有评价。欢迎分享你的使用感受。

评论

无需登录即可发表。欢迎分享使用感受、提问,或说明在哪些环境下无法运行。

还没有评论。来写第一条吧。

提交后会立即公开。请勿填写邮箱、电话等个人信息。URL 最多 2 个。

0 / 1000 字

此表单受 reCAPTCHA 保护,适用 Google 的隐私权政策和服务条款。

同一仓库的技能

aeon

免费

Analyze time series, observations ordered over time, using aeon in Python. Build classification, prediction, and clustering workflows, detect unusual patterns or changes, and compare methods through an interface compatible with scikit-learn.

中文简介正在准备中。当前显示英语简介。

  • Classifying time series by their patterns
  • Forecasting future values from past observations
  • Detecting anomalies and change points
foryourhealth111-pixel/Vibe-Skills37642026年10月23日 更新

Create original generative art with p5.js, using code to produce patterns and motion. Receive a written artistic concept and an interactive HTML viewer with adjustable parameters, reproducible random variations, seed navigation, and PNG downloads.

中文简介正在准备中。当前显示英语简介。

  • Create art from particle motion and flow fields
  • Explore patterns by adjusting sliders
  • Reproduce a favorite variation with the same seed
foryourhealth111-pixel/Vibe-Skills37642026年10月23日 更新

Retrieve stock prices, exchange rates, cryptocurrency prices, company financial statements, and economic indicators through the Alpha Vantage API. It also covers historical data, news sentiment, and technical indicators, which summarize price and trading patterns.

中文简介正在准备中。当前显示英语简介。

  • Retrieve historical stock prices and trading volumes
  • Collect company financial statements and earnings data
  • Check foreign exchange and cryptocurrency prices
foryourhealth111-pixel/Vibe-Skills37642026年10月23日 更新

Design backend systems with clear boundaries between business rules, databases, and external services. Use Clean Architecture, Hexagonal Architecture, and Domain-Driven Design to organize new applications, refactor existing code, and make core logic easier to test.

中文简介正在准备中。当前显示英语简介。

  • Planning the structure of a new backend
  • Refactoring tightly coupled applications
  • Testing business rules independently of external services
foryourhealth111-pixel/Vibe-Skills37642026年10月23日 更新

astropy

免费

Helps process astronomical data in Python by converting coordinates, units, and time scales, working with FITS observation files, matching object catalogs, and calculating distances using cosmological models.

中文简介正在准备中。当前显示英语简介。

  • Converting celestial coordinates
  • Reading and editing FITS observation files
  • Matching objects across astronomical catalogs
foryourhealth111-pixel/Vibe-Skills37642026年10月23日 更新

Carry a software project from requirements and design through implementation, testing, debugging, and deployment. Tracks progress in files, works through features incrementally, and resumes interrupted development, supporting new projects and broad refactoring efforts.

中文简介正在准备中。当前显示英语简介。

  • Building a new project from a specification
  • Resuming an interrupted development project
  • Developing features across multiple implementation steps
foryourhealth111-pixel/Vibe-Skills37642026年10月23日 更新

查看 foryourhealth111-pixel 的全部技能

报告此技能的问题