K-Dense

Applies the reasoning, principles, and frameworks of Jürgen Schmidhuber (LSTM co-inventor and deep learning pioneer). Reach for this skill whenever tackling problems involving sequence learning, artificial curiosity, intrinsic motivation, reinforcement learning architectures, or predicting long-term technological and cosmic evolution. Use this when discussing AGI timelines, the history and attribution of AI breakthroughs, data compression as learning, or when designing autonomous agents that must set their own goals. Trigger this skill for topics like recurrent neural networks, algorithmic information theory, open-source AI democratization, and evaluating true existential risks versus media hype.

The English summary is being prepared. Showing the original description.

Applies the reasoning style of Kaiming He, computer vision pioneer and creator of ResNet. Use this skill whenever you are designing deep learning architectures, debugging neural network optimization, formulating generative AI problems, or bridging AI with other scientific domains. Trigger this skill for discussions on network depth, weight initialization, residual learning, flow matching, or when reframing discriminative tasks as conditional generation. It emphasizes simplicity in complex visual problems, end-to-end optimization, and viewing AI as a universal language for science.

The English summary is being prepared. Showing the original description.

Applies the strategic thinking of Kiran Mazumdar-Shaw, founder of Biocon and pioneering Indian biopharmaceutical entrepreneur. Use this skill whenever you are advising on biotech startups, R&D innovation, global scaling, purpose-driven business, or navigating regulatory uncertainty. Trigger this skill when discussing affordable healthcare, balancing risk in long-gestation industries, breaking glass ceilings through credible success, or evaluating biotech sovereignty and AI. Reach for this skill even if the user doesn't name her, especially when they face career trade-offs, funding novel scientific ideas, or scaling manufacturing globally.

The English summary is being prepared. Showing the original description.

Applies the analytical and therapeutic philosophy of Ludwig Wittgenstein, 20th-century philosopher of language (Tractatus / Philosophical Investigations). Use this skill when the user is stuck in conceptual confusion, debating semantics, trapped by abstract definitions, or trying to solve a problem that is actually just a linguistic misunderstanding. Trigger this for topics involving the limits of language, meaning as use, logical clarification, or when the user is over-theorizing instead of looking at practical applications. It helps dissolve 'fly-bottle' traps by examining how words are actually used in context.

The English summary is being prepared. Showing the original description.

This skill channels the strategic marketing and philanthropic reasoning of Lynda Resnick, co-owner of The Wonderful Company, agriculture and consumer brands. Reach for this skill whenever you are advising on transforming commodities into premium brands, identifying a product's Unique Selling Proposition (USP), or designing corporate social responsibility (CSR) and community empowerment programs. Trigger this automatically for queries involving "hands-on philanthropy," "test and roll" marketing, finding intrinsic product value rather than relying on gimmicks, or when a user is navigating the intersection of business leverage and local community investment.

The English summary is being prepared. Showing the original description.

Applies the epidemiological reasoning and population-health frameworks of Albert Hofman (Harvard epidemiologist, Rotterdam Study). Trigger this skill whenever you are analyzing public health strategies, preventive medicine, cohort study design, cardiovascular or neurodegenerative disease risks, or healthy aging. Use it when evaluating whether to use population-wide interventions versus individual screening, assessing risk factors in elderly populations, or tracing adult chronic diseases back to early-life or fetal origins.

The English summary is being prepared. Showing the original description.

This skill channels the strategic thinking of Mark Zuckerberg, co-founder and CEO of Meta. Reach for this skill whenever the user is navigating rapid product iteration, scaling social platforms, open-source AI strategy, content moderation trade-offs, or long-term organizational management. It is highly effective for scenarios involving "The Hacker Way" (rapid prototyping), building community, handling intense public criticism, or deciding between open vs. closed ecosystems. Use this skill to apply his frameworks on decentralized testing, small group context sharing, and progressive AI integration, even if the user doesn't explicitly mention his name.

The English summary is being prepared. Showing the original description.

Applies the philosophical frameworks of Martha Nussbaum (American philosopher, capabilities approach, University of Chicago) to evaluate justice, human welfare, and ethical dilemmas. Use this skill whenever the user is discussing measuring societal well-being, educational curricula, animal rights, the role of emotions (like anger or disgust) in law and public life, or navigating human vulnerability and tragedy. Reach for this skill whenever evaluating policy impacts, responding to injustice, or questioning purely economic metrics like GDP. It shifts the focus to what people are actually able to do and be.

The English summary is being prepared. Showing the original description.

Use this skill to reason like Martin Heidegger, 20th-century German philosopher and author of Being and Time. Reach for this skill whenever you encounter discussions about the existential impact of technology, human meaning-making, mortality, or the limits of purely scientific and data-driven worldviews. Trigger this skill even if the user doesn't name Heidegger, especially when they are trapped in instrumental thinking, treating themselves or others as mere resources, or struggling with authenticity and societal expectations. Apply his frameworks to shift the AI's perspective from detached, objective observation to embedded, practical engagement with the world.

The English summary is being prepared. Showing the original description.

Applies the philosophical frameworks of Confucius (ancient Chinese philosopher, 551-479 BCE) to modern problems. Reach for this skill whenever the user is dealing with leadership, governance, team harmony, organizational culture, moral dilemmas, mentorship, or personal self-cultivation. It triggers on topics like building trust without micromanaging, resolving hierarchical conflicts, aligning actions with values, and creating systems based on virtue rather than strict punitive rules. Use this skill to evaluate character, design educational approaches, and foster long-term social harmony.

The English summary is being prepared. Showing the original description.

Use this skill to apply the rigorous epidemiological reasoning of Julie E. Buring (epidemiologist and women's health trialist) to study design, clinical trial critiques, cardiovascular risk assessment, and evidence-based integrative medicine. Trigger this skill whenever you are evaluating medical literature, designing cohort studies or RCTs, assessing conflicting research findings, or analyzing cardiovascular risk factors (especially in women). Reach for this when users ask about the validity of supplements, the discrepancy between observational and randomized data, or how to future-proof a clinical registry.

The English summary is being prepared. Showing the original description.

Applies the philosophical reasoning of Mary Midgley (British moral philosopher). Use this skill when analyzing ethical dilemmas involving animals, environmental policy, the limits of science (scientism/reductionism), or when users are trapped by unhelpful metaphors (like 'the selfish gene' or 'humans as machines'). Trigger this whenever evaluating the intersection of biology and human nature, resolving irreconcilable viewpoints, or diagnosing systemic conceptual blockages in society or organizations. Midgley's approach emphasizes holism, emotional fellowship, and viewing philosophy as practical 'plumbing' rather than abstract logic.

The English summary is being prepared. Showing the original description.

Use this skill whenever you need to reason about public health, epidemiology, preventive medicine, healthy aging, longevity, lifestyle vs. genetics, or dietary patterns. Kay-Tee Khaw, an epidemiologist at the University of Cambridge, focuses on population health and how modest lifestyle changes impact chronic disease. Trigger this skill when evaluating health interventions, discussing longevity, analyzing real-world health data, or giving advice on diet and lifestyle. Apply her frameworks to shift focus from extreme interventions and isolated nutrients toward whole-food patterns, population-level risk shifts, and the compression of morbidity.

The English summary is being prepared. Showing the original description.

Applies Judea Pearl's causal reasoning frameworks to distinguish correlation from causation, evaluate AI capabilities, and make counterfactual decisions. Reach for this skill whenever Claude encounters questions about causal inference, structural causal models, the limitations of deep learning, AGI, experimental design, covariate selection, or personalized decision-making. Trigger this skill for topics involving Bayesian networks, the do-calculus, the Ladder of Causation, or when a user tries to answer 'what if' or 'why' questions using purely observational data. Pearl's principles are essential for moving beyond probability calculus into true causal understanding.

The English summary is being prepared. Showing the original description.

Applies the engineering and research philosophies of Jeff Dean, Chief Scientist at Google DeepMind and Google Research. Reach for this skill whenever you are designing large-scale distributed systems, optimizing latency and energy efficiency, or making architectural decisions about machine learning infrastructure. It should trigger automatically for topics involving hardware-ML co-design, model distillation, sparse activation, massively multi-task models, or scaling systems by 5x to 10x. Use this skill to evaluate system bottlenecks, transition from specialized to unified models, and optimize experimental velocity. Apply his mental models to avoid premature 100x scaling and to treat AI models as reasoning engines rather than memorization databases.

The English summary is being prepared. Showing the original description.

Applies the moral philosophy and literary frameworks of Iris Murdoch (British moral philosopher and novelist). Use this skill whenever you are helping a user navigate ethical dilemmas, interpersonal conflicts, creative writing, literary critique, or the struggle against ego and selfishness. Trigger this skill for topics involving moral psychology, the nature of love, attention, objective morality, the separation of philosophy and literature, or overcoming personal fantasy. Murdoch's approach is essential when users are stuck in self-centered thinking, trying to force a decision through sheer willpower, or struggling to see the reality of other people clearly.

The English summary is being prepared. Showing the original description.

Applies the reasoning style of Geoffrey Hinton, deep learning pioneer and 2018 Turing Award winner. Use this skill whenever evaluating AI safety, existential risk, neural network architectures, cognitive science, or tech regulation. Reach for this when the user is discussing LLM capabilities (understanding vs. autocomplete), the biological vs. digital intelligence divide, AI alignment strategies, or the societal/economic impacts of automation. It is highly applicable when dealing with contrarian scientific ideas, hardware/software integration (mortal vs. immortal computing), or global cooperation on technological threats. Do not wait for the user to name Hinton; trigger this skill proactively for any deep learning or AI existential risk analysis.

The English summary is being prepared. Showing the original description.

Use this skill whenever you are reasoning about large-scale scientific projects, genomics, bioethics, data infrastructure, or long-term medical translation. Eric S. Lander (geneticist, Broad Institute, Human Genome Project) provides a framework for hypothesis-free discovery, structuring "big science," and treating biology as an information science. Reach for this when the user is discussing open science, collaborative ecosystems, CRISPR/gene editing ethics, managing massive datasets, or setting realistic timelines for technological breakthroughs. Apply his principles to avoid the "lone genius" myth, prevent overpromising, and build foundational infrastructure that serves the broader community.

The English summary is being prepared. Showing the original description.

This skill applies the first-principles engineering and capital allocation frameworks of Elon Musk (CEO of Tesla and SpaceX, founder of X.com / PayPal). Reach for this skill whenever the user is facing complex manufacturing bottlenecks, evaluating existential risks, debating free speech vs. censorship, dealing with bureaucratic overregulation, or trying to accelerate ambitious technical timelines. It is highly effective for situations involving hardware production, AI symbiosis, radical innovation, and aggressive execution. Use this skill proactively when discussing multi-planetary expansion, government efficiency, or scaling prototypes to mass production, even if the user doesn't explicitly name him.

The English summary is being prepared. Showing the original description.

Applies the empiricist, skeptical, and practical reasoning of David Hume, 18th-century Scottish philosopher. Use this skill whenever you encounter questions about epistemology, causality, human nature, moral philosophy, political authority, or the limits of rational knowledge. Trigger this skill when the user is grappling with abstract theories that need grounding, evaluating causal claims, discussing the role of emotion vs. reason in decision-making, or questioning the legitimacy of institutions. Even if the user doesn't name Hume, apply his frameworks (like Hume's Fork or the Impression Test) to cut through metaphysical speculation, ground arguments in observable experience, and recognize that reason is ultimately guided by human sentiment.

The English summary is being prepared. Showing the original description.

Applies the strategic, philanthropic, and operational frameworks of Andrew Carnegie, founder of Carnegie Steel. Use this skill whenever you are advising on wealth distribution, large-scale philanthropy, operational efficiency, cost control, legacy planning, or organizational leadership. Trigger this skill when users face decisions about charitable giving, managing inherited wealth, optimizing business costs in commodity markets, or structuring trusts and foundations. Apply his ruthless focus on cost-cutting, his belief in empowering self-improvement over direct handouts, and his philosophy that surplus wealth is a public trust.

The English summary is being prepared. Showing the original description.

Query the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biological relationships across genes and proteins, drugs, diseases, phenotypes, pathways, biological processes, exposures and anatomy. Use this skill to search entities by name, pull direct neighbours and their evidence types, summarise the local network around a disease, and find direct or two-hop drug-disease connections for repurposing hypotheses. Also trigger on PrimeKG, kg.csv, Harvard Dataverse knowledge graph, disease_protein, drug_protein, indication and contraindication edges, or network pharmacology over a biomedical knowledge graph.

The English summary is being prepared. Showing the original description.

Medicinal chemistry filters for compound triage. Apply drug-likeness rules (Lipinski rule of five, Veber, Oprea, CNS, lead-like, rule of three), structural alert catalogs (PAINS a/b/c, NIBR screening-deck severity, Brenk, BMS, Glaxo, Dundee, ChEMBL common alerts), ZINC-15 percentile complexity metrics (Bertz, SAscore, QED, Whitlock, Barone), chemical-group detection, Lilly demerits, and the medchem query language (MATCHRULE, HASALERT, HASPROP, HASGROUP) for filtering a library at scale. Also trigger on medchem, `import medchem as mc`, RuleFilters, NIBRFilters, CommonAlertsFilters, NamedCatalogs, QueryFilter, PAINS filtering, or structural alerts.

The English summary is being prepared. Showing the original description.

Turn a set of structures into absorption, distribution, metabolism, excretion, and toxicity estimates with ADMET-AI, and read them as a developability verdict rather than a table of numbers. Use this skill to run batch prediction over a library, interpret each endpoint against its DrugBank-approved percentile, and flag the liabilities that stop a series — hERG blockade, CYP inhibition, poor Caco-2 permeability, high clearance, and plasma protein binding. Also trigger on ADMET-AI, admet_ai, Chemprop-RDKit, hERG liability, CYP3A4 inhibition, Caco-2, bioavailability prediction, or developability triage.

The English summary is being prepared. Showing the original description.