Results for “opa”

Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hierarchical orthologous groups, eggNOG-mapper, JustOrthologs, and TOGA whole-genome-alignment orthology. Use when building single-copy ortholog sets for phylogenomics, classifying co-orthologs and in/out-paralogs after gene duplication, propagating functional annotation via orthology with awareness of the ortholog conjecture, distinguishing speciation from duplication via gene-tree species-tree reconciliation, computing Quest-for-Orthologs benchmark performance, or running synteny-aware ortholog detection in WGD-affected lineages.

The English summary is being prepared. Showing the original description.

Time-blind friendly planning, executive function support, and daily structure for ADHD brains. Specializes in realistic time estimation, dopamine-aware task design, and building systems that actually work for neurodivergent minds.

The English summary is being prepared. Showing the original description.

Italian electronic invoicing and payments through Openapi - send/receive electronic invoices via SDI (Sistema di Interscambio), digital receipts (scontrino elettronico), legal storage, and bill payments (MAV, RAV, PagoPA, car tax). Use for fatturazione elettronica and bill payment tasks.

The English summary is being prepared. Showing the original description.

Walks a cardiologist through whether, where and how to order a germline genetic test for a suspected inherited cardiovascular disease: indication, written consent (with assent for minors), pre-test counseling, choice of test and laboratory, handling of VUS and secondary findings, and privacy. Use when a clinician asks 'should I order a genetic test', 'how do I consent for a cardiomyopathy or long QT gene panel', 'can I test this child or relative (cascade screening)', 'what do I tell the patient about VUS or a negative result', or 'where can this test be sent'. Based on the JCS/JCC/JSPCCS 2024 guideline; Japan-specific insurance and legal details are flagged.

The English summary is being prepared. Showing the original description.

This skill checks for contraindications or sources of inaccuracy that may affect continuous glucose monitoring (CGM) reliability in hospitalized adults. It is triggered when clinicians ask, “Are there factors that could make CGM unreliable?” or when assessing for skin infection, hypoperfusion, hypovolemia, vasoactive/pressor therapy, or medications such as acetaminophen >4 g/day, dopamine, vitamin C, or hydroxyurea.

The English summary is being prepared. Showing the original description.

Screen a hypercalcemic patient for medication- and supplement-induced causes — thiazides, lithium, vitamin D, vitamin A/retinoids, antiestrogens, theophylline, milk-alkali, SGLT2 inhibitors, immune checkpoint inhibitors, denosumab rebound, teriparatide/abaloparatide, foscarnet, ketogenic diet, aluminium. Trigger when a clinician asks "is this hypercalcemia drug-induced", "thiazide hypercalcemia", "lithium hypercalcemia", "denosumab rebound hypercalcemia", "vitamin D toxicity", "milk-alkali syndrome", "SGLT2 hypercalcemia", or any new hypercalcemia where medication review is needed.

The English summary is being prepared. Showing the original description.

Selects spironolactone as first-line mineralocorticoid receptor antagonist for bilateral primary aldosteronism, with eplerenone as an alternative when spironolactone–related adverse effects are problematic. Trigger phrases include 'confirmed bilateral PA on AVS', 'idiopathic adrenal hyperplasia', 'bilateral adrenal hyperplasia', 'glucocorticoid-remediable aldosteronism', and 'initiating medical therapy for bilateral adrenal disease'.

The English summary is being prepared. Showing the original description.

Recommends withdrawing interfering medications and repeating aldosterone-to-renin ratio screening when initial screen is negative but clinical suspicion remains due to hypokalemia or medication interference. Trigger phrases include "initial screen negative", "hypokalemia", "resistant hypertension", and use of MRAs, ACE inhibitors, ARBs, beta-blockers, clonidine, or alpha-methyldopa.

The English summary is being prepared. Showing the original description.

Helps distinguish unilateral from bilateral adrenal disease based on 18-oxocortisol levels, which are typically higher in aldosterone-producing adenoma than idiopathic adrenal hyperplasia. Use when evaluating 18-oxocortisol results during PA workup to guide subtype classification after a positive ARR.

The English summary is being prepared. Showing the original description.

Differentiates aldosterone-producing adenoma from idiopathic adrenal hyperplasia based on 18-hydroxycorticosterone levels, with APA patients generally having levels >100 ng/dL at 8:00 a.m. and IAH patients usually having levels <100 ng/dL. Use when reviewing 18-OHB test results to help subtype PA; triggers include 18-OHB >100 ng/dL (suggesting APA) or <100 ng/dL (suggesting IAH).

The English summary is being prepared. Showing the original description.

Expert-level nanomaterials engineering covering synthesis, characterization, properties at nanoscale, nanocomposites, safety, and industrial applications of nanomaterials.

The English summary is being prepared. Showing the original description.

Expert-level seismology covering earthquake seismology, seismic wave propagation, seismometer instrumentation, earthquake source parameters, seismic hazard, and induced seismicity.

The English summary is being prepared. Showing the original description.

Expert-level acoustics knowledge. Use when working with sound waves, acoustic propagation, resonance, standing waves, Doppler effect, room acoustics, ultrasound, noise control, musical acoustics, or architectural acoustics. Also use when the user mentions 'sound wave', 'decibel', 'frequency', 'resonance', 'standing wave', 'Doppler effect', 'acoustic impedance', 'reverberation', 'ultrasound', 'noise control', 'harmonics', or 'sound intensity'.

The English summary is being prepared. Showing the original description.

Use to consolidate multiple already-run judge verdicts into one report — consensus, conflicts, must-fix/should-fix with per-judge provenance. Consume-only, no opaque score, never auto-gates.

The English summary is being prepared. Showing the original description.

[Skill Management] Use when shared protocol checklists change and need propagating across skills.

The English summary is being prepared. Showing the original description.

Operates domains and DNS: registrars, Cloudflare zones and records, nameserver delegation, vanity domains, redirects, and DNS/HTTP verification. Use when setting up or debugging DNS records, redirects, or propagation.

The English summary is being prepared. Showing the original description.

Detect and prevent privilege escalation in Kubernetes pods by monitoring security contexts, capabilities, and syscall patterns with Falco and OPA policies.

The English summary is being prepared. Showing the original description.

Auditing Terraform infrastructure-as-code for security misconfigurations using Checkov, tfsec, Terrascan, and OPA/Rego policies to detect overly permissive IAM policies, public resource exposure, missing encryption, and insecure defaults before cloud deployment.

The English summary is being prepared. Showing the original description.

Use when working on Nuxt 4+ projects - provides server routes, file-based routing, middleware patterns, Nuxt-specific composables, and configuration with latest docs. Covers h3 v1 helpers (validation, WebSocket, SSE) and nitropack v2 patterns. Updated for Nuxt 4.3+.

The English summary is being prepared. Showing the original description.

Knowledge base from the NASA Probabilistic Risk Assessment Procedures Guide (NASA/SP-2011-3421, 2nd ed.). Use for quantitative PRA of aerospace and safety-critical systems: the risk triplet and scenario logic stack (MLD, ESD, event trees, fault trees, minimal cut sets), Bayesian data collection and parameter estimation, aleatory/epistemic uncertainty modeling and common-cause failure (Alpha Factor, beta-factor, CCBE), human reliability analysis (THERP, CREAM, NARA, SPAR-H), context-based software risk (CSRM), physics-based and structural/phenomenological models (stress-strength, limit states, FORM/SORM, NASGRO, range safety), uncertainty propagation and importance measures (F-V, RAW, Birnbaum, DIM), and launch-abort modeling with worked PRA examples. This is the QUANTITATIVE engine beneath NASA's risk doctrine — for the qualitative RIDM/CRM decision framework use the nasa-risk pack. Thin on programme management, organisational risk governance, and non-aerospace regulatory contexts; aerospace-focused and anchored to the 2011 second edition.

The English summary is being prepared. Showing the original description.

Baut und betreibt ein anbieterneutrales Self-Care-Kernset für geplante LLM-Aufgaben und Desktop-App-Automationen. Ergänzt deterministisches Policy-Linting, Lock- und Modell-Governance, semantische Prompt-Prüfung, konsistente Mehrflächen-Updates, Mini-Checks und Regeldatei-Hygiene. Nutzen, wenn ein Agent seinen nativen Scheduler entdecken oder eine bestehende Automations-Flotte mit Rollback, Readback und Löschschutz kontinuierlich verbessern soll. Löst aus bei automation self-care, Scheduler-Task-Pflege, Desktop-App-Automations-Wartung, Automations-Flotten-Audit, selbstheilende Zeitpläne, core-set-textautomations, basic-text-automations, textbased-automation-core, textbased-automation-drivers, textbased-governance-automations oder textbased-desktopapp-automations.

The English summary is being prepared. Showing the original description.

Ensure designs define trust boundaries, authn/authz responsibilities, and propagation of identity/claims across services.

The English summary is being prepared. Showing the original description.

WAAPI and compositing: production-level GPU-friendly transform/opacity, offscreen pausing. Use when implementing, reviewing or testing waapi and compositing for React, Vite, Next.js or Perfect_AI projects.

The English summary is being prepared. Showing the original description.

Master error handling patterns across languages including exceptions, Result types, error propagation, and graceful degradation to build resilient applications. Use when implementing error handling, designing APIs, or improving application reliability.

The English summary is being prepared. Showing the original description.