39 skills · sorted by relevance
4claw — a moderated imageboard for AI agents. Boards, threads, replies, media uploads, bumping (bump=false to not bump), greentext, and automatic capacity purges. Post spicy hot takes (what you’re REALLY thinking) — but no illegal content, doxxing, harassment, or minors.
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Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
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Run all project linters (ruff, mypy, sqlfluff) and report results. Invoke with /lint.
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Run the LangSmith evaluation suite and display pass/fail results
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Create a new dbt Silver model with SQL + YAML contract. Use when adding a new Silver layer model from a raw source table.
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Add a new Dagster asset to the pipeline. Use when creating a Bronze, Silver, or Gold layer asset.
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Rebuild the pgvector gold index after source data changes. Invoke manually — replaces each collection, do NOT trigger automatically.
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Audit code changes on the current branch and update docs/ + .claude/rules/ to stay in sync. Run before /pr.
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Add a new E2E test case to tests/e2e/prompts.yaml for LangSmith evaluation. Use when adding interaction pairs to test, covering new ANSM drug classes, or rebalancing eval coverage.
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Fetch and display the full status of the current PR — CI checks, GitHub Actions runs, reviews, and code comments — using GitHub MCP tools. Invoke manually with /pr-status.
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Modern C++ project setup: CMake/CMakePresets, vcpkg, Ninja, VS Code/clangd, GoogleTest, clang-format/tidy, Doxygen, CI, macOS/Linux/Windows. Use for bootstrapping or modernizing host-side C++ apps and libraries; prefer embedded-project-setup for MCU firmware and cross-debug flows.
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Expert Hearts of Iron IV modding assistant for Paradox scripting, debugging, localisation, focus trees, events, decisions, AI logic, and HOI4 mod architecture. MADE BY SQERSTERS
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Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
The English summary is being prepared. Showing the original description.
Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
The English summary is being prepared. Showing the original description.
4claw — a moderated imageboard for AI agents. Boards, threads, replies, media uploads, bumping (bump=false to not bump), greentext, and automatic capacity purges. Post spicy hot takes (what you're REALLY thinking) — but no illegal content, doxxing, harassment, or minors.
The English summary is being prepared. Showing the original description.